Howard Hiatt
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Howard Haym Hiatt (July 22, 1925 – March 2, 2024) was an American medical researcher involved with the discovery of
messenger RNA In molecular biology, messenger ribonucleic acid (mRNA) is a single-stranded molecule of RNA that corresponds to the genetic sequence of a gene, and is read by a ribosome in the process of synthesizing a protein. mRNA is created during the ...
. He was the onetime chair of the department of medicine at Beth Israel Hospital in Boston from 1963 to 1972. He was dean of the
Harvard School of Public Health The Harvard T.H. Chan School of Public Health is the public health school at Harvard University, located in the Longwood Medical Area of Boston, Massachusetts. It was named after Hong Kong entrepreneur Chan Tseng-hsi in 2014 following a US$350 ...
from 1972 to 1984. He was co-founder and associate chief of the Division of Social Medicine and Health Inequalities at the
Brigham and Women's Hospital Brigham and Women's Hospital (BWH or The Brigham) is a teaching hospital of Harvard Medical School and the largest hospital in the Longwood Medical Area in Boston, Massachusetts. Along with Massachusetts General Hospital, it is one of the two ...
, and was also the Associate Chief of the hospital's Division of Global Health Equity.Brigham and Women's Hospital profile page for Howard Hiatt
/ref> He was a founding head of the cancer division of Beth Israel Hospital (now
Beth Israel Deaconess Medical Center Beth Israel Deaconess Medical Center (BIDMC) in Boston, Massachusetts is a teaching hospital of Harvard Medical School and one of the founding members of Beth Israel Lahey Health. It was formed out of the 1996 merger of Beth Israel Hospital (f ...
). He was a member of the team at the
Pasteur Institute The Pasteur Institute (, ) is a French non-profit private foundation dedicated to the study of biology, micro-organisms, diseases, and vaccines. It is named after Louis Pasteur, who invented pasteurization and vaccines for anthrax and rabies. Th ...
, Paris, led by
François Jacob François Jacob (; 17 June 1920 – 19 April 2013) was a French biologist who, together with Jacques Monod, originated the idea that control of enzyme levels in all cells occurs through regulation of transcription. He shared the 1965 Nobel ...
and
Jacques Monod Jacques Lucien Monod (; 9 February 1910 – 31 May 1976) was a French biochemist who won the Nobel Prize in Physiology or Medicine in 1965, sharing it with François Jacob and André Lwoff "for their discoveries concerning genetic control of e ...
, which first identified and described
messenger RNA In molecular biology, messenger ribonucleic acid (mRNA) is a single-stranded molecule of RNA that corresponds to the genetic sequence of a gene, and is read by a ribosome in the process of synthesizing a protein. mRNA is created during the ...
, and he was part of the team led by
James Watson James Dewey Watson (born April 6, 1928) is an American molecular biology, molecular biologist, geneticist, and zoologist. In 1953, he co-authored with Francis Crick the academic paper in ''Nature (journal), Nature'' proposing the Nucleic acid ...
that was among the first to demonstrate messenger RNA in mammalian cells. Hiatt was married for 60 years to Doris Bieringer, a librarian who co-founded a reference publication for high-school libraries. Hiatt was a member of the Board of Sponsors of the ''
Bulletin of the Atomic Scientists The ''Bulletin of the Atomic Scientists'' is a nonprofit organization concerning science and global security issues resulting from accelerating technological advances that have negative consequences for humanity. The ''Bulletin'' publishes conte ...
''.


Early life and education

Howard Haym Hiatt was born in
Patchogue, New York Patchogue ( ) is a Administrative divisions of New York#Village, village in Suffolk County, New York. The population was 12,408 at the time of the 2020 census. The Incorporated Village of Patchogue is an incorporated community in the Town (New ...
, in 1925 to a Jewish family. His father was an immigrant from
Lithuania Lithuania, officially the Republic of Lithuania, is a country in the Baltic region of Europe. It is one of three Baltic states and lies on the eastern shore of the Baltic Sea, bordered by Latvia to the north, Belarus to the east and south, P ...
who lost much of his family in the
Holocaust The Holocaust (), known in Hebrew language, Hebrew as the (), was the genocide of History of the Jews in Europe, European Jews during World War II. From 1941 to 1945, Nazi Germany and Collaboration with Nazi Germany and Fascist Italy ...
; he immigrated alone to the United States, where he changed his surname to "Hiatt" from "Chaitowicz" at
Ellis Island Ellis Island is an island in New York Harbor, within the U.S. states of New Jersey and New York (state), New York. Owned by the U.S. government, Ellis Island was once the busiest immigrant inspection and processing station in the United State ...
. Howard enrolled in
Harvard College Harvard College is the undergraduate education, undergraduate college of Harvard University, a Private university, private Ivy League research university in Cambridge, Massachusetts, United States. Part of the Harvard Faculty of Arts and Scienc ...
in 1944, and received his medical degree in 1948 from the
Harvard Medical School Harvard Medical School (HMS) is the medical school of Harvard University and is located in the Longwood Medical and Academic Area, Longwood Medical Area in Boston, Massachusetts. Founded in 1782, HMS is the third oldest medical school in the Un ...
. He was trained in clinical medicine, biochemistry, and molecular biology.


Career

Hiatt was a
Harvard University Harvard University is a Private university, private Ivy League research university in Cambridge, Massachusetts, United States. Founded in 1636 and named for its first benefactor, the History of the Puritans in North America, Puritan clergyma ...
faculty member beginning in 1955. Hiatt was the first Blumgart Professor of Medicine at Harvard Medical School, as well as the physician-in-chief at Beth Israel Hospital in
Boston Boston is the capital and most populous city in the Commonwealth (U.S. state), Commonwealth of Massachusetts in the United States. The city serves as the cultural and Financial centre, financial center of New England, a region of the Northeas ...
, from 1963 to 1972. During his tenure there, Beth Israel became one of the first teaching hospitals to translate molecular and cell biology to clinical problems and to develop teaching and research programs in primary care. In 1972, Hiatt was planning to go to
Yale Yale University is a private Ivy League research university in New Haven, Connecticut, United States. Founded in 1701, Yale is the third-oldest institution of higher education in the United States, and one of the nine colonial colleges ch ...
as the dean of its medical school, when the then-new president of Harvard University asked him to stay as dean of the
Harvard School of Public Health The Harvard T.H. Chan School of Public Health is the public health school at Harvard University, located in the Longwood Medical Area of Boston, Massachusetts. It was named after Hong Kong entrepreneur Chan Tseng-hsi in 2014 following a US$350 ...
. While he was dean from 1972 to 1984, the school strengthened and greatly broadened its work in quantitative analytic sciences, introduced molecular and cell biology into its research and teaching, began its program in health policy and management—the first in a public health school, and promoted integration of its teaching and research programs with those in other Harvard Faculties. As of 1985, he was Professor of Medicine at
Harvard Medical School Harvard Medical School (HMS) is the medical school of Harvard University and is located in the Longwood Medical and Academic Area, Longwood Medical Area in Boston, Massachusetts. Founded in 1782, HMS is the third oldest medical school in the Un ...
and Senior Physician at
Brigham and Women's Hospital Brigham and Women's Hospital (BWH or The Brigham) is a teaching hospital of Harvard Medical School and the largest hospital in the Longwood Medical Area in Boston, Massachusetts. Along with Massachusetts General Hospital, it is one of the two ...
. He helped develop the Research Training in Clinical Effectiveness Program, which trains physicians to carry out research on issues of quality and costs of medical care. His later research concerned social aspects of health. He helped launch and for his last ten years was Associate Chief of the Division of Global Health Equity. Hiatt was a member of the Board of Directors of Partners in Health and a member emeritus of the Task Force for Global Health. An accomplished physician, researcher, mentor, and teacher, and a leader in the field of human rights, his work was widely published and often appeared in both scholarly and lay publications.


Publications

Hiatt had numerous research articles in publications such as the ''
Journal of Molecular Biology The ''Journal of Molecular Biology'' is a biweekly peer-reviewed scientific journal covering all aspects of molecular biology. It was established in 1959 by Academic Press in London. It is currently published by Elsevier. The editor-in-chief was P ...
'', ''
Journal of Biological Chemistry The ''Journal of Biological Chemistry'' (''JBC'') is a weekly peer-reviewed scientific journal that was established in 1905., jbc.org Since 1925, it is published by the American Society for Biochemistry and Molecular Biology. It covers research i ...
'', the ''
New England Journal of Medicine ''The New England Journal of Medicine'' (''NEJM'') is a weekly medical journal published by the Massachusetts Medical Society. Founded in 1812, the journal is among the most prestigious peer-reviewed medical journals. Its 2023 impact factor was ...
'', and the ''
Journal of the American Medical Association ''JAMA'' (''The Journal of the American Medical Association'') is a peer-reviewed medical journal published 48 times a year by the American Medical Association. It publishes original research, reviews, and editorials covering all aspects of ...
''. He wrote for the lay press in areas of disease prevention, health services, and the health implications of the nuclear arms race. His book, ''Medical Lifeboat: Will There Be Room for You in the Health Care System?'' (published in January 1989 by Harper & Row) outlined methods for addressing some very basic problems of the American healthcare system.


Personal life

Hiatt was married to Doris Bieringer, a librarian who co-founded a reference publication for high-school libraries, from 1947 until her death in 2007. His father-in-law, Walter H. Bieringer, was active in the Boston area's Jewish Community Council. Beringer served as president of the United Service for New Americans which helped to resettle European Jews in the United States after
World War II World War II or the Second World War (1 September 1939 – 2 September 1945) was a World war, global conflict between two coalitions: the Allies of World War II, Allies and the Axis powers. World War II by country, Nearly all of the wo ...
. Hiatt also served as vice-president of the Associated Jewish Philanthropies of Boston, and as a member of a presidential committee. This committee advised the
Truman Administration Harry S. Truman's tenure as the List of presidents of the United States, 33rd president of the United States began on April 12, 1945, upon the death of President Franklin D. Roosevelt, and ended on January 20, 1953. He had been Vice President ...
on displaced persons before being named Head of Massachusetts Commission on Refugees in 1957. Hiatt died from
pulmonary hypertension Pulmonary hypertension (PH or PHTN) is a condition of increased blood pressure in the pulmonary artery, arteries of the lungs. Symptoms include dypsnea, shortness of breath, Syncope (medicine), fainting, tiredness, chest pain, pedal edema, swell ...
at his home in
Cambridge, Massachusetts Cambridge ( ) is a city in Middlesex County, Massachusetts, United States. It is a suburb in the Greater Boston metropolitan area, located directly across the Charles River from Boston. The city's population as of the 2020 United States census, ...
, on March 2, 2024, at the age of 98.


Awards

In 2011,
Dartmouth College Dartmouth College ( ) is a Private university, private Ivy League research university in Hanover, New Hampshire, United States. Established in 1769 by Eleazar Wheelock, Dartmouth is one of the nine colonial colleges chartered before the America ...
awarded Hiatt an honorary Doctor of Science (D.Sc.) degree, noting his long career devoted to "improving health care services through care, teaching, research, and advocacy".


See also

*
Comparative effectiveness research Comparative effectiveness research (CER) is the direct comparison of existing health care interventions to determine which work best for which patients and which pose the greatest benefits and harms. The core question of comparative effectiveness r ...
*
Messenger RNA In molecular biology, messenger ribonucleic acid (mRNA) is a single-stranded molecule of RNA that corresponds to the genetic sequence of a gene, and is read by a ribosome in the process of synthesizing a protein. mRNA is created during the ...


References


External links


October 2011 video: beginning at 17:15, Howard Hiatt, who served as Dean from 1972 to 1984, discusses his tenure leading HSPH.

Howard Hiatt discusses his life and his wife, Doris, whom he married after her education
at
Wellesley College Wellesley College is a Private university, private Women's colleges in the United States, historically women's Liberal arts colleges in the United States, liberal arts college in Wellesley, Massachusetts, United States. Founded in 1870 by Henr ...

Conaboy, C. 02-21-2013 Boston Globe feature on Dr. Howard Hiatt



Harvard Catalyst profile for Howard H. Hiatt, includes very complete bibliography

''Harvard Public Health Review'', 75th Anniversary Issues, Volume 11, shows Hiatt as 5th Dean of HSPH, from 1972-1984, page 3, and pages 10-16
- Hiatt had urged closer community health cooperation between the
Harvard School of Public Health The Harvard T.H. Chan School of Public Health is the public health school at Harvard University, located in the Longwood Medical Area of Boston, Massachusetts. It was named after Hong Kong entrepreneur Chan Tseng-hsi in 2014 following a US$350 ...
and the local neighborhoods, including adjacent
Mission Hill, Boston Mission Hill is a square mile (2 square km), primarily residential neighborhood of Boston, bordered by Roxbury, Jamaica Plain and Fenway-Kenmore and the town of Brookline. The neighborhood has two main streets, namely Tremont Street and Hu ...
(page 11).
Profile page for Howard Hiatt at Harvard Medical School's Department of Global Health and Social Medicine



Dartmouth College, 2011, Howard Hiatt awarded an honorary Doctor of Science (D.Sc.) from Dartmouth College

Howard H. Hiatt Papers, 1940-2001 (inclusive), 1975-2001 (bulk), H MS c314. Harvard Medical Library, Francis A. Countway Library of Medicine, Boston, Massachusetts.
{{DEFAULTSORT:Hiatt, Howard 1925 births 2024 deaths 20th-century American Jews 20th-century American physicians 21st-century American Jews American medical researchers American people of Lithuanian-Jewish descent Harvard College alumni Harvard Medical School alumni Jewish American scientists Members of the National Academy of Medicine People from Patchogue, New York Physician-scientists