Homospermidine synthase () is an
enzyme
An enzyme () is a protein that acts as a biological catalyst by accelerating chemical reactions. The molecules upon which enzymes may act are called substrate (chemistry), substrates, and the enzyme converts the substrates into different mol ...
with
systematic name
A systematic name is a name given in a systematic way to one unique group, organism, object or chemical substance, out of a specific population or collection. Systematic names are usually part of a nomenclature.
A semisystematic name or semitrivi ...
''putrescine:putrescine 4-aminobutyltransferase (ammonia-forming)''.
This enzyme
catalyses the following
chemical reaction
A chemical reaction is a process that leads to the chemistry, chemical transformation of one set of chemical substances to another. When chemical reactions occur, the atoms are rearranged and the reaction is accompanied by an Gibbs free energy, ...
: (1) 2
putrescine
Putrescine is an organic compound with the formula (CH2)4(NH2)2. It is a colorless solid that melts near room temperature. It is classified as a diamine. Together with cadaverine, it is largely responsible for the foul odor of Putrefaction, putref ...
sym-homospermidine + NH
3 + H
+
: (2) putrescine +
spermidine
Spermidine is a polyamine compound () found in ribosomes and living tissues and having various metabolic functions within organisms.
Function
Spermidine is an Aliphatic compound, aliphatic polyamine. Spermidine synthase (SPDS) catalyzes its form ...
sym-homospermidine + propane-1,3-diamine
The reaction of this enzyme occurs in three steps.
See also
DHPS
Deoxyhypusine synthase is an enzyme that in humans is encoded by the ''DHPS'' gene.
The unusual amino acid hypusine is formed posttranslationally and is only found in a single cellular protein, eukaryotic translation initiation factor 5A ( EIF5A ...
References
External links
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