Holosystolic
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Systolic heart murmurs are
heart murmurs Heart murmurs are unique heart sounds produced when blood flows across a heart valve or blood vessel. This occurs when turbulent blood flow creates a sound loud enough to hear with a stethoscope. The sound differs from normal heart sounds by t ...
heard during
systole Systole ( ) is the part of the cardiac cycle during which some chambers of the heart contract after refilling with blood. Its contrasting phase is diastole, the relaxed phase of the cardiac cycle when the chambers of the heart are refilling ...
, i.e. they begin and end between S1 and S2. Many involve stenosis of the
semilunar valves A heart valve is a biological Check valve, one-way valve that allows blood flow, blood to flow in one direction through the chambers of the heart. A mammalian heart usually has four valves. Together, the valves determine the direction of blood flow ...
or regurgitation of the
atrioventricular valves A heart valve is a biological one-way valve that allows blood to flow in one direction through the chambers of the heart. A mammalian heart usually has four valves. Together, the valves determine the direction of blood flow through the heart. Hear ...
.


Types

* Mid-systolic ejection murmurs are due to blood flow through the
semilunar valves A heart valve is a biological Check valve, one-way valve that allows blood flow, blood to flow in one direction through the chambers of the heart. A mammalian heart usually has four valves. Together, the valves determine the direction of blood flow ...
. They occur at the start of blood ejection — which starts after S1 — and ends with the cessation of the blood flow — which is before S2. Therefore, the onset of a midsystolic ejection murmur is separated from S1 by the isovolumic contraction phase; the cessation of the murmur and the S2 interval is the aortic or pulmonary hangout time. The resultant configuration of this murmur is a crescendo-decrescendo murmur. Causes of midsystolic ejection murmurs include outflow obstruction, increased flow through normal semilunar valves, dilation of aortic root or pulmonary trunk, or structural changes in the semilunar valves without obstruction. * Late systolic murmurs start after S1 and, if left sided, extend up to S2, usually in a crescendo manner. Causes include mitral valve prolapse, tricuspid valve prolapse and
papillary muscle The papillary muscles are muscles located in the ventricles of the heart. They attach to the cusps of the atrioventricular valves (also known as the mitral and tricuspid valves) via the chordae tendineae and contract to prevent inversion or ...
dysfunction. * Holosystolic (pansystolic) murmurs start at S1 and extend up to S2. They are usually due to regurgitation in cases such as mitral regurgitation, tricuspid regurgitation, or ventricular septal defect (VSD).


Individual murmurs


Mid-systolic ejection


Late systolic


Holosystolic (pansystolic)


References

{{Cardiovascular system symptoms and signs Heart murmurs