Heteroglycan Alpha-mannosyltransferase
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In
enzymology An enzyme () is a protein that acts as a biological catalyst by accelerating chemical reactions. The molecules upon which enzymes may act are called substrate (chemistry), substrates, and the enzyme converts the substrates into different mol ...
, a heteroglycan alpha-mannosyltransferase () is an
enzyme An enzyme () is a protein that acts as a biological catalyst by accelerating chemical reactions. The molecules upon which enzymes may act are called substrate (chemistry), substrates, and the enzyme converts the substrates into different mol ...
that
catalyzes Catalysis () is the increase in rate of a chemical reaction due to an added substance known as a catalyst (). Catalysts are not consumed by the reaction and remain unchanged after it. If the reaction is rapid and the catalyst recycles quick ...
the
chemical reaction A chemical reaction is a process that leads to the chemistry, chemical transformation of one set of chemical substances to another. When chemical reactions occur, the atoms are rearranged and the reaction is accompanied by an Gibbs free energy, ...
:GDP-mannose + heteroglycan \rightleftharpoons GDP + 2(or 3)-alpha-D-mannosyl-heteroglycan Thus, the two substrates of this enzyme are
GDP-mannose Guanosine diphosphate mannose or GDP-mannose is a nucleotide sugar that is a substrate for glycosyltransferase reactions in metabolism. This compound is a substrate for enzymes called mannosyltransferases. Known as donor of activated mannose in a ...
and heteroglycan, whereas its 3
products Product may refer to: Business * Product (business), an item that can be offered to a market to satisfy the desire or need of a customer. * Product (project management), a deliverable or set of deliverables that contribute to a business solution ...
are
GDP Gross domestic product (GDP) is a monetary measure of the total market value of all the final goods and services produced and rendered in a specific time period by a country or countries. GDP is often used to measure the economic performance o ...
, 2-alpha-D-mannosyl-heteroglycan, and 3-alpha-D-mannosyl-heteroglycan. This enzyme belongs to the family of
glycosyltransferase Glycosyltransferases (GTFs, Gtfs) are enzymes ( EC 2.4) that establish natural glycosidic linkages. They catalyze the transfer of saccharide moieties from an activated nucleotide sugar (also known as the "glycosyl donor") to a nucleophilic gl ...
s, to be specific the hexosyltransferases. The
systematic name A systematic name is a name given in a systematic way to one unique group, organism, object or chemical substance, out of a specific population or collection. Systematic names are usually part of a nomenclature. A semisystematic name or semitrivi ...
of this enzyme class is GDP-mannose:heteroglycan 2-(or 3-)-alpha-D-mannosyltransferase. Other names in common use include GDP mannose alpha-mannosyltransferase, and guanosine diphosphomannose-heteroglycan alpha-mannosyltransferase.


References

* EC 2.4.1 Enzymes of unknown structure {{2.4-enzyme-stub