Henri Bounameaux
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Henri Bounameaux is a professor of medicine specialized in
internal Internal may refer to: *Internality as a concept in behavioural economics *Neijia, internal styles of Chinese martial arts *Neigong or "internal skills", a type of exercise in meditation associated with Daoism * ''Internal'' (album) by Safia, 2016 ...
and vascular medicine (angiology), as well as general medicine. Bounameaux served as the Dean of Faculty of Medicine at the University of Geneva, Switzerland. He is an emeritus professor at the University of Geneva and served as president of the Swiss Academy of Medical Sciences (SAMS) from 2020 to 2024. Bounameaux's research interests relate to the prevention, diagnosis, and treatment of
venous thromboembolism Venous thrombosis is the blockage of a vein caused by a thrombus (blood clot). A common form of venous thrombosis is deep vein thrombosis (DVT), when a blood clot forms in the deep veins. If a thrombus breaks off ( embolizes) and flows to the lun ...
. His main contribution to the field relates to the non-invasive work-up of suspected
pulmonary embolism Pulmonary embolism (PE) is a blockage of an pulmonary artery, artery in the lungs by a substance that has moved from elsewhere in the body through the bloodstream (embolism). Symptoms of a PE may include dyspnea, shortness of breath, chest pain ...
, particularly the use of fibrin
D-dimer D-dimer (or D dimer) is a dimer that is a fibrin degradation product (FDP), a small protein fragment present in the blood after a blood clot is degraded by fibrinolysis. It is so named because it contains two D fragments of the fibrin protein ...
. He was among the first scientists in the late eighties to suggest that this dosage in the patient plasma allowed to safely rule out
venous thromboembolism Venous thrombosis is the blockage of a vein caused by a thrombus (blood clot). A common form of venous thrombosis is deep vein thrombosis (DVT), when a blood clot forms in the deep veins. If a thrombus breaks off ( embolizes) and flows to the lun ...
, which was demonstrated in subsequent publications of the Geneva research group.


Early life and education

Bounameaux was born in 1953 and spent his early childhood in the
Belgian Congo The Belgian Congo (, ; ) was a Belgian colonial empire, Belgian colony in Central Africa from 1908 until independence in 1960 and became the Republic of the Congo (Léopoldville). The former colony adopted its present name, the Democratic Repu ...
(now the
Democratic Republic of the Congo The Democratic Republic of the Congo (DRC), also known as the DR Congo, Congo-Kinshasa, or simply the Congo (the last ambiguously also referring to the neighbouring Republic of the Congo), is a country in Central Africa. By land area, it is t ...
), living in
Lubumbashi Lubumbashi ( , ; former ; former ) is the second-largest Cities of the Democratic Republic of the Congo, city in the Democratic Republic of the Congo, located in the country's southeasternmost part, along the border with Zambia. The capital ...
until 1967. His father Yves Bounameaux was Chief of medicine and Dean of the Faculty of medicine there. After relocating to
Switzerland Switzerland, officially the Swiss Confederation, is a landlocked country located in west-central Europe. It is bordered by Italy to the south, France to the west, Germany to the north, and Austria and Liechtenstein to the east. Switzerland ...
at the age of 14, he pursued medical studies at the
University of Basel The University of Basel (Latin: ''Universitas Basiliensis''; German: ''Universität Basel'') is a public research university in Basel, Switzerland. Founded on 4 April 1460, it is Switzerland's oldest university and among the world's oldest univ ...
, where he earned his medical degree in 1978. He later moved to
Geneva Geneva ( , ; ) ; ; . is the List of cities in Switzerland, second-most populous city in Switzerland and the most populous in French-speaking Romandy. Situated in the southwest of the country, where the Rhône exits Lake Geneva, it is the ca ...
in 1980, where he established his clinical and academic career. Bounameaux completed his primary and secondary education in
Lubumbashi Lubumbashi ( , ; former ; former ) is the second-largest Cities of the Democratic Republic of the Congo, city in the Democratic Republic of the Congo, located in the country's southeasternmost part, along the border with Zambia. The capital ...
(then
Belgian Congo The Belgian Congo (, ; ) was a Belgian colonial empire, Belgian colony in Central Africa from 1908 until independence in 1960 and became the Republic of the Congo (Léopoldville). The former colony adopted its present name, the Democratic Repu ...
, later
Zaïre Zaire, officially the Republic of Zaire, was the name of the Democratic Republic of the Congo from 1971 to 18 May 1997. Located in Central Africa, it was, by area, the third-largest country in Africa after Sudan and Algeria, and the 11th-la ...
) and obtained a Baccalauréat Type C in 1971 from St.-Louis, France. He received his medical degree and post-graduate specialization from the Faculty of Medicine,
University of Basel The University of Basel (Latin: ''Universitas Basiliensis''; German: ''Universität Basel'') is a public research university in Basel, Switzerland. Founded on 4 April 1460, it is Switzerland's oldest university and among the world's oldest univ ...
, and is board-certified in internal and vascular medicine (angiology). He completed the post-doctoral education from Center for Thrombosis and Vascular Research, Belgium.


Career

Following clinical training in internal medicine at hospitals in
Basel Basel ( ; ), also known as Basle ( ), ; ; ; . is a city in northwestern Switzerland on the river Rhine (at the transition from the High Rhine, High to the Upper Rhine). Basel is Switzerland's List of cities in Switzerland, third-most-populo ...
,
Montreux Montreux (, ; ; ) is a Municipalities of Switzerland, Swiss municipality and List of towns in Switzerland, town on the shoreline of Lake Geneva at the foot of the Swiss Alps, Alps. It belongs to the Riviera-Pays-d'Enhaut (district), Riviera-Pays ...
, and
Geneva Geneva ( , ; ) ; ; . is the List of cities in Switzerland, second-most populous city in Switzerland and the most populous in French-speaking Romandy. Situated in the southwest of the country, where the Rhône exits Lake Geneva, it is the ca ...
, he completed a two-year postdoctoral fellowship at the University of Leuven in
Belgium Belgium, officially the Kingdom of Belgium, is a country in Northwestern Europe. Situated in a coastal lowland region known as the Low Countries, it is bordered by the Netherlands to the north, Germany to the east, Luxembourg to the southeas ...
. In 1985, he returned to the
Geneva University Hospitals The Geneva University Hospitals (, HUG) is one of the five Teaching hospital, university hospitals of Switzerland and the largest one in the country. It is one of the List of hospitals by capacity, largest hospitals in Europe. First founded ...
(Hôpitaux Universitaires de Genève, HUG), where he would spend the remainder of his clinical and academic career. He was appointed assistant physician in 1988 and, in 1993, became head of the Angiology and Hemostasis Service within the Department of Internal Medicine at HUG, a position he held until 2016. From 2002 to 2010, he also served as head of the Department of Internal Medicine. In academia, Bounameaux became a Privat-docent in 1988, was promoted to associate professor in 1997, and was named full professor in 2002 in the Faculty of Medicine at the
University of Geneva The University of Geneva (French: ''Université de Genève'') is a public university, public research university located in Geneva, Switzerland. It was founded in 1559 by French theologian John Calvin as a Theology, theological seminary. It rema ...
. From 2010 to 2012, Bounameaux chaired the Council of the International Society on Thrombosis and Haemostasis (ISTH) after having organized its world congress in Geneva (2007). He was awarded the ISTH Distinguished Career Award in 2009 in recognition of his scientific contributions. In 2011, he was elected Dean of the Faculty of Medicine at the
University of Geneva The University of Geneva (French: ''Université de Genève'') is a public university, public research university located in Geneva, Switzerland. It was founded in 1559 by French theologian John Calvin as a Theology, theological seminary. It rema ...
, a role he held for two consecutive terms until 2019. Concurrently, he also served as Director of Teaching and Research at HUG. In 2015, Bounameaux was elected as an individual member of the Swiss Academy of Medical Sciences. During his presidency (2020-2024), the Academy initiated a project aiming to reform in depth the Swiss health system. He was named Honorary Professor of the
University of Geneva The University of Geneva (French: ''Université de Genève'') is a public university, public research university located in Geneva, Switzerland. It was founded in 1559 by French theologian John Calvin as a Theology, theological seminary. It rema ...
in July 2019.


Research

Bounameaux's research interests are broad and include studies in non-invasive vascular diagnosis, venous thromboembolism and pulmonary embolism, cardiology, angiology and hemostasis. His main contribution to the field relates to the non-invasive work-up of suspected pulmonary embolism, particularly the use of fibrin D-dimer. He was among the first scientists in the late eighties to suggest that this dosage in the patient plasma allowed to safely rule out venous thromboembolism, which was demonstrated in subsequent publications of the Geneva research group. Bounameaux is known for his contributions to the understanding, diagnosis, and treatment of
venous thromboembolism Venous thrombosis is the blockage of a vein caused by a thrombus (blood clot). A common form of venous thrombosis is deep vein thrombosis (DVT), when a blood clot forms in the deep veins. If a thrombus breaks off ( embolizes) and flows to the lun ...
(VTE), with a particular emphasis on thrombosis, pulmonary embolism, and the use of anticoagulants. His work has influenced clinical practice in the non-invasive diagnosis and management of thromboembolic disease. Throughout his career, he has explored the implications of thromboembolism in cancer patients, surgical settings, and critical care. From 2010 to 2021, Bounameaux’s more recent work has focused on the clinical course of VTE in oncology, clot resolution dynamics following anticoagulation, and the management of right heart thrombi. His research during this period continued to integrate mortality risk analysis and treatment outcomes, often employing statistical tools such as hazard ratios and confidence intervals to inform evidence-based care.


Personal life

In 1976, Bounameaux married Anne Carreau, M.Sc. (mathematics). The couple has two daughters: Claire (born in 1979), who is the mother of four children, and Dominique (born in 1982), who has two daughters. Outside of his professional activities, Bounameaux has maintained a long-standing interest in equestrian sports, particularly eventing, in which he has actively supported his daughter Dominique and granddaughter Lou.


Awards

During his career, Bounameaux has received the following awards and honors: * Theodor-Naegeli International Thrombosis Award * President of the Swiss Society of Angiology * Président of the Société d’Angiologie de Langue Française * Chairman of the ISTH Council * Distinguished Career Award from ISTH *Honorary member of the Swiss Society of Angiology *Honorary Fellow of the Swiss School of Public Health


Publications

* ''Measurement of D-dimer in plasma as diagnostic aid in suspected pulmonary embolism''. * ''Diagnosis of pulmonary embolism by a noninvasive decision analysis-based strategy including clinical probability, D-Dimer levels, and ultrasonography: A Management Study'' * ''Factor V Leiden Paradox: Risk of Deep Vein Thrombosis but not of Pulmonary embolism''. * ''Multidetector-Row Computed Tomography in Suspected Pulmonary Embolism''. *''D-dimer for Venous Thromboembolism Diagnosis: Twenty Years Later''. *''Oral Rivaroxaban for the Treatment of Symptomatic Pulmonary Embolism''. * * * * * * *


References


External links


Henri Bounameaux
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Henri Bounameaux
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. {{DEFAULTSORT:Bounameaux, Henri Living people Academic staff of the University of Basel Academic staff of the University of Geneva Year of birth missing (living people)