Hemogenic endothelium or haemogenic endothelium is a special subset of endothelial cells scattered within blood vessels that can differentiate into

haematopoietic Haematopoiesis (; ; also hematopoiesis in American English, sometimes h(a)emopoiesis) is the formation of blood cellular components. All cellular blood components are derived from haematopoietic stem cells. In a healthy adult human, roughly ten b ...

cells. The development of hematopoietic cells in the embryo proceeds sequentially from

mesoderm The mesoderm is the middle layer of the three germ layers that develops during gastrulation in the very early development of the embryo of most animals. The outer layer is the ectoderm, and the inner layer is the endoderm.Langman's Medical ...

through the

hemangioblast Hemangioblasts are the multipotent precursor cells that can differentiate into both hematopoietic stem cells, hematopoietic and endothelial cells. In the mouse embryo, the emergence of blood islands in the yolk sac at embryonic day 7 marks the ons ...

to the hemogenic endothelium and hematopoietic progenitors. The relationship between the hemogenic endothelium and the hemangioblast is not clearly understood.

References

Cell biology Hematopoiesis Embryology of cardiovascular system {{Molecular-cell-biology-stub

See also

References