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The Heaf test, a
diagnostic Diagnosis (: diagnoses) is the identification of the nature and cause of a certain phenomenon. Diagnosis is used in a lot of different academic discipline, disciplines, with variations in the use of logic, analytics, and experience, to determine " ...
skin test, was long performed to determine whether or not children had been exposed to
tuberculosis Tuberculosis (TB), also known colloquially as the "white death", or historically as consumption, is a contagious disease usually caused by ''Mycobacterium tuberculosis'' (MTB) bacteria. Tuberculosis generally affects the lungs, but it can al ...
infection. The test was named after F. R. G. Heaf. Also known as the Sterneedle test, it was administered by a Heaf gun (trademarked "Sterneedle"), a spring-loaded instrument with six needles arranged in a circular formation which was inserted in the wrist or shoulder. The Heaf test was discontinued in 2005 because the manufacturer deemed its production to be financially unsustainable after manufacturers could not be found for
tuberculin Tuberculin, also known as purified protein derivative, is a combination of proteins that are used in the diagnosis of tuberculosis. This use is referred to as the tuberculin skin test and is recommended only for those at high risk. Reliable adm ...
or Heaf guns. Until 2005, the test was used in the United Kingdom to determine if the BCG vaccine was needed; the
Mantoux test The Mantoux test or Mendel–Mantoux test (also known as the Mantoux screening test, tuberculin sensitivity test, Pirquet test, or PPD test for purified protein derivative) is a tool for screening (medicine), screening for tuberculosis, tuberculo ...
is now used instead. The Heaf test was preferred in the UK, because it was thought to be easier to interpret, with less variability between observers, and less training was required to administer and read the test. Patients who exhibited a negative reaction to the
test Test(s), testing, or TEST may refer to: * Test (assessment), an educational assessment intended to measure the respondents' knowledge or other abilities Arts and entertainment * ''Test'' (2013 film), an American film * ''Test'' (2014 film) ...
were considered for BCG vaccination. The Heaf test was used to test for tuberculosis in
adolescents Adolescence () is a transitional stage of human physical and psychological development that generally occurs during the period from puberty to adulthood (typically corresponding to the age of majority). Adolescence is usually associated with ...
aged around 13–14. __TOC__


Procedure

A Heaf gun was used to inject multiple samples of testing serum under the skin at once. The needle points were dipped in tuberculin purified protein derivative (PPD) and pricked into the skin. A Heaf gun with disposable single-use heads was recommended. The gun injected PPD equivalent to 100,000 units per ml to the skin over the flexor surface of the left forearm in a circular pattern of six. The test was read between two and seven days later. The injection could not be into sites containing superficial veins. The reading of the Heaf test was defined by a scale: * Negative – no induration, maybe six minute puncture scars * Grade 1 – four to six
papules A papule is a small, well-defined bump in the skin. It may have a rounded, pointed or flat top, and may have a dip. It can appear with a stalk, be thread-like or look warty. It can be soft or firm and its surface may be rough or smooth. Some ...
(also considered negative) * Grade 2 – confluent papules form indurated ring (positive) * Grade 3 – central filling to form disc (positive) * Grade 4 – disc >10 mm with or without blistering (strongly positive) Grades 1 and 2 could result from previous BCG or avian tuberculosis, rather than human TB infection. Children who were found to have a grade 3 or 4 reaction were referred for
X-ray An X-ray (also known in many languages as Röntgen radiation) is a form of high-energy electromagnetic radiation with a wavelength shorter than those of ultraviolet rays and longer than those of gamma rays. Roughly, X-rays have a wavelength ran ...
and follow-up. For interpretation of the test, see Tuberculosis diagnosis.


Other tests

The equivalent
Mantoux test The Mantoux test or Mendel–Mantoux test (also known as the Mantoux screening test, tuberculin sensitivity test, Pirquet test, or PPD test for purified protein derivative) is a tool for screening (medicine), screening for tuberculosis, tuberculo ...
positive levels done with 10 TU (0.1 mL 100 TU/mL, 1:1000) are * 0–4 mm induration (Heaf 0-1) * 5–14 mm induration (Heaf 2) * >15 mm induration (Heaf 3-4) The
Mantoux test The Mantoux test or Mendel–Mantoux test (also known as the Mantoux screening test, tuberculin sensitivity test, Pirquet test, or PPD test for purified protein derivative) is a tool for screening (medicine), screening for tuberculosis, tuberculo ...
is preferred in the
United States The United States of America (USA), also known as the United States (U.S.) or America, is a country primarily located in North America. It is a federal republic of 50 U.S. state, states and a federal capital district, Washington, D.C. The 48 ...
for the diagnosis of tuberculosis; multiple puncture tests, such as the Heaf test and Tine test, are not recommended.


References

* Joint Tuberculosis Committee of the British Thoracic Society,
Control and prevention of tuberculosis in the United Kingdom: Code of Practice 2000
' BMJ 2000:55:887-901
Table 3 Heaf Test
grading, reaction, and equivalent Mantoux positive levels. {{Tuberculosis Immunologic tests Tuberculosis