The Hazardous Substances Data Bank (HSDB) was a
toxicology
Toxicology is a scientific discipline, overlapping with biology, chemistry, pharmacology, and medicine, that involves the study of the adverse effects of chemical substances on living organisms and the practice of diagnosing and treating ex ...
database on the U.S.
National Library of Medicine
The United States National Library of Medicine (NLM), operated by the United States federal government, is the world's largest medical library.
Located in Bethesda, Maryland, the NLM is an institute within the National Institutes of Health. I ...
's (NLM) Toxicology Data Network (TOXNET).
It focused on the toxicology of potentially hazardous chemicals, and included information on human exposure,
industrial hygiene
Occupational hygiene or industrial hygiene (IH) is the anticipation, recognition, evaluation, control, and confirmation (ARECC) of protection from risks associated with exposures to hazards in, or arising from, the workplace that may result in ...
, emergency handling procedures, environmental fate, regulatory requirements, and related areas. All data were referenced and derived from a core set of books, government documents, technical reports, and selected primary journal literature. Prior to 2020, all entries were peer-reviewed by a Scientific Review Panel (SRP), members of which represented a spectrum of professions and interests. Last Chairs of the SRP are Dr. Marcel J. Cassavant, MD, Toxicology Group, and Dr. Roland Everett Langford, PhD, Environmental Fate Group. The SRP was terminated due to budget cuts and realignment of the NLM.
The HSDB was organized into individual chemical records, and contained over 5000 such records.
It was accessible free of charge via TOXNET. Users could search by chemical or other name, chemical name fragment,
CAS registry number and/or subject terms. Recent additions included radioactive materials and certain mixtures, like crude oil and oil dispersants as well as animal toxins. , there were approximately 5,600 chemical specific HSDB records available.
TOXNET databases
The Toxicology Data Network (TOXNET) was a group of databases hosted on the
National Library of Medicine
The United States National Library of Medicine (NLM), operated by the United States federal government, is the world's largest medical library.
Located in Bethesda, Maryland, the NLM is an institute within the National Institutes of Health. I ...
(NLM) website that covered "chemicals and drugs, diseases and the environment, environmental health, occupational safety and health, poisoning, risk assessment and regulations, and toxicology".
TOXNET was managed by the NLM's Toxicology and Environmental Health Information Program (TEHIP) in the Division of Specialized Information Services (SIS).
The TOXNET databases included:
#HSDB: Hazardous Substances Data Bank
#*Peer-reviewed toxicology data for over 5,000 hazardous chemicals
#
TOXLINE
#*4 million references to literature on biochemical, pharmacological, physiological, and toxicological effects of drugs and other chemicals
#
ChemIDplus
#*Dictionary of over 400,000 chemicals (names, synonyms, and structures)
#
LactMed: Drugs and Lactation Database
#*Drugs and other chemicals to which breastfeeding mothers may be exposed
#DART: Developmental and Reproductive Toxicology Database
#*References to developmental and reproductive toxicology literature
#
TOXMAP
TOXMAP was a geographic information system (GIS) from the United States National Library of Medicine (NLM) that was deprecated on December 16, 2019. The application used maps of the United States to help users explore data from the United States E ...
#*Environmental Health Maps provides searchable, interactive maps of EPA TRI and Superfund data, plus US Census and NCI health data
#TRI:
Toxics Release Inventory
The Toxics Release Inventory (TRI) is a publicly available database containing information on toxic chemical releases and other waste management activities in the United States.
Summary of requirements
The database is available from the United ...
#*Annual environmental releases of over 600 toxic chemicals by U.S. facilities
#CTD:
Comparative Toxicogenomics Database
#*Access to scientific data describing relationships between chemicals, genes and human diseases
#Household Products Database
#*Potential health effects of chemicals in more than 10,000 common household products
#Haz-Map
#*Links jobs and hazardous tasks with occupational diseases and their symptoms
#IRIS: Integrated Risk Information System
#*Hazard identification and dose-response assessment for over 500 chemicals
#ITER: International Toxicity Estimates for Risk
#*Risk information for over 600 chemicals from authoritative groups worldwide
#ALTBIB
#* Resources on Alternatives to the Use of Live Vertebrates in Biomedical Research and Testing
References
External links
TOXNET information
{{Portal bar, United States
Biochemistry databases
Chemical safety
Toxicology
Chemical databases
Breastfeeding