Hartmut Michel (; born 18 July 1948) is a German

biochemist Biochemists are scientists who are trained in biochemistry. They study chemical processes and chemical transformations in living organisms. Biochemists study DNA, proteins and cell parts. The word "biochemist" is a portmanteau of "biological che ...

, who received the 1988

Nobel Prize in Chemistry ) , image = Nobel Prize.png , alt = A golden medallion with an embossed image of a bearded man facing left in profile. To the left of the man is the text "ALFR•" then "NOBEL", and on the right, the text (smaller) "NAT•" then "M ...

for determination of the first crystal structure of an integral membrane protein, a membrane-bound complex of proteins and co-factors that is essential to

photosynthesis Photosynthesis is a process used by plants and other organisms to convert light energy into chemical energy that, through cellular respiration, can later be released to fuel the organism's activities. Some of this chemical energy is stored i ...

Education and early life

He was born on 18 July 1948 in

Ludwigsburg Ludwigsburg (; Swabian: ''Ludisburg'') is a city in Baden-Württemberg, Germany, about north of Stuttgart city centre, near the river Neckar. It is the largest and primary city of the Ludwigsburg district with about 88,000 inhabitants. It is ...

. After compulsory military service, he studied biochemistry at the

University of Tübingen The University of Tübingen, officially the Eberhard Karl University of Tübingen (german: Eberhard Karls Universität Tübingen; la, Universitas Eberhardina Carolina), is a public research university located in the city of Tübingen, Baden-W� ...

, working for his final year at Dieter Oesterhelt's laboratory on

ATPase ATPases (, Adenosine 5'-TriPhosphatase, adenylpyrophosphatase, ATP monophosphatase, triphosphatase, SV40 T-antigen, ATP hydrolase, complex V (mitochondrial electron transport), (Ca2+ + Mg2+)-ATPase, HCO3−-ATPase, adenosine triphosphatase) are ...

activity of

halobacteria Haloarchaea (halophilic archaea, halophilic archaebacteria, halobacteria) are a class of the Euryarchaeota, found in water saturated or nearly saturated with salt. Halobacteria are now recognized as archaea rather than bacteria and are one of th ...

Career and research

Hartmut later worked on the crystallisation of

membrane protein Membrane proteins are common proteins that are part of, or interact with, biological membranes. Membrane proteins fall into several broad categories depending on their location. Integral membrane proteins are a permanent part of a cell membrane ...

s - essential for their structure elucidation by

X-ray crystallography X-ray crystallography is the experimental science determining the atomic and molecular structure of a crystal, in which the crystalline structure causes a beam of incident X-rays to diffract into many specific directions. By measuring the angle ...

. He received the

Nobel Prize The Nobel Prizes ( ; sv, Nobelpriset ; no, Nobelprisen ) are five separate prizes that, according to Alfred Nobel's will of 1895, are awarded to "those who, during the preceding year, have conferred the greatest benefit to humankind." Alfre ...

jointly with

Johann Deisenhofer Johann Deisenhofer (; born September 30, 1943) is a German biochemist who, along with Hartmut Michel and Robert Huber, received the Nobel Prize for Chemistry in 1988 for their determination of the first crystal structure of an integral membrane ...

and

Robert Huber Robert Huber (; born 20 February 1937) is a German biochemist and Nobel laureate. known for his work crystallizing an intramembrane protein important in photosynthesis and subsequently applying X-ray crystallography to elucidate the protein's st ...

in 1988. Together with Michel and Huber, Deisenhofer determined the three-dimensional structure of a protein complex found in certain photosynthetic bacteria. This membrane protein complex, called a photosynthetic reaction center, was known to play a crucial role in initiating a simple type of photosynthesis. Between 1982 and 1985, the three scientists used

to determine the exact arrangement of the more than 10,000 atoms that make up the protein complex. Their research increased the general understanding of the mechanisms of photosynthesis, revealed similarities between the photosynthetic processes of plants and bacteria and established a methodology for crystallising membrane proteins. Since 1987 he has been director of the Molecular Membrane Biology department at the Max Planck Institute for Biophysics in

Frankfurt am Main Frankfurt, officially Frankfurt am Main (; Hessian dialects, Hessian: , "Franks, Frank ford (crossing), ford on the Main (river), Main"), is the most populous city in the States of Germany, German state of Hesse. Its 791,000 inhabitants as o ...

, Germany, and professor of biochemistry at the

Goethe University Frankfurt Goethe University (german: link=no, Johann Wolfgang Goethe-Universität Frankfurt am Main) is a university located in Frankfurt am Main, Germany. It was founded in 1914 as a citizens' university, which means it was founded and funded by the wealt ...

Awards and honours

In 1986, he received the

Gottfried Wilhelm Leibniz Prize The Gottfried Wilhelm Leibniz Prize (german: link=no, Förderpreis für deutsche Wissenschaftler im Gottfried Wilhelm Leibniz-Programm der Deutschen Forschungsgemeinschaft), in short Leibniz Prize, is awarded by the German Research Foundation to ...

of the

Deutsche Forschungsgemeinschaft The German Research Foundation (german: Deutsche Forschungsgemeinschaft ; DFG ) is a German research funding organization, which functions as a self-governing institution for the promotion of science and research in the Federal Republic of Germ ...

, which is the highest honour awarded in German research. In 1988, he received the

. He received the Bijvoet Medal at the Bijvoet Center for Biomolecular Research of

Utrecht University Utrecht University (UU; nl, Universiteit Utrecht, formerly ''Rijksuniversiteit Utrecht'') is a public research university in Utrecht, Netherlands. Established , it is one of the oldest universities in the Netherlands. In 2018, it had an enrollm ...

in 1989. In 1995 he became a member of the

German Academy of Sciences Leopoldina The German National Academy of Sciences Leopoldina (german: link=no, Deutsche Akademie der Naturforscher Leopoldina – Nationale Akademie der Wissenschaften), short Leopoldina, is the national academy of Germany, and is located in Halle (Saal ...

. He also became a foreign member of the

Royal Netherlands Academy of Arts and Sciences The Royal Netherlands Academy of Arts and Sciences ( nl, Koninklijke Nederlandse Akademie van Wetenschappen, abbreviated: KNAW) is an organization dedicated to the advancement of science and literature in the Netherlands. The academy is housed ...

in 1995. He was elected a Foreign Member of the Royal Society (ForMemRS) in 2005.

References

External links

* {{DEFAULTSORT:Michel, Hartmut 1948 births Members of the European Molecular Biology Organization Foreign associates of the National Academy of Sciences Living people German biochemists Nobel laureates in Chemistry German Nobel laureates Gottfried Wilhelm Leibniz Prize winners Foreign Members of the Royal Society Foreign members of the Chinese Academy of Sciences Members of the Royal Netherlands Academy of Arts and Sciences Max Planck Society people Commanders Crosses of the Order of Merit of the Federal Republic of Germany Recipients of the Order of Merit of Baden-Württemberg Academic staff of Goethe University Frankfurt Scientists from Frankfurt Researchers of photosynthesis Bijvoet Medal recipients Members of the German Academy of Sciences Leopoldina University of Tübingen alumni Max Planck Institute directors