Hans Fischer (; 27 July 1881 – 31 March 1945) was a German
organic chemist
Organic chemistry is a subdiscipline within chemistry involving the science, scientific study of the structure, properties, and reactions of organic compounds and organic matter, organic materials, i.e., matter in its various forms that contain ...
and the recipient of the 1930
Nobel Prize for Chemistry
The Nobel Prize in Chemistry () is awarded annually by the Royal Swedish Academy of Sciences to scientists in the various fields of chemistry. It is one of the five Nobel Prizes established by the will of Alfred Nobel in 1895, awarded for outst ...
"for his researches into the constitution of
haemin and
chlorophyll
Chlorophyll is any of several related green pigments found in cyanobacteria and in the chloroplasts of algae and plants. Its name is derived from the Greek words (, "pale green") and (, "leaf"). Chlorophyll allows plants to absorb energy ...
and especially for his synthesis of haemin."
Biography
Early years
Fischer was born on July 27, 1881, in
Höchst, now a city district of
Frankfurt
Frankfurt am Main () is the most populous city in the States of Germany, German state of Hesse. Its 773,068 inhabitants as of 2022 make it the List of cities in Germany by population, fifth-most populous city in Germany. Located in the forela ...
located in Germany. His parents were Dr. Eugen Fischer, Director of the firm of ,
Wiesbaden
Wiesbaden (; ) is the capital of the German state of Hesse, and the second-largest Hessian city after Frankfurt am Main. With around 283,000 inhabitants, it is List of cities in Germany by population, Germany's 24th-largest city. Wiesbaden form ...
, and Privatdozent at the Technical High School,
Stuttgart
Stuttgart (; ; Swabian German, Swabian: ; Alemannic German, Alemannic: ; Italian language, Italian: ; ) is the capital city, capital and List of cities in Baden-Württemberg by population, largest city of the States of Germany, German state of ...
, and Anna Herdegen was his mother. He went to a primary school in Stuttgart, and later to the "Humanistisches
Gymnasium" in
Wiesbaden
Wiesbaden (; ) is the capital of the German state of Hesse, and the second-largest Hessian city after Frankfurt am Main. With around 283,000 inhabitants, it is List of cities in Germany by population, Germany's 24th-largest city. Wiesbaden form ...
, matriculating in 1899. He read
chemistry
Chemistry is the scientific study of the properties and behavior of matter. It is a physical science within the natural sciences that studies the chemical elements that make up matter and chemical compound, compounds made of atoms, molecules a ...
and
medicine
Medicine is the science and Praxis (process), practice of caring for patients, managing the Medical diagnosis, diagnosis, prognosis, Preventive medicine, prevention, therapy, treatment, Palliative care, palliation of their injury or disease, ...
, first at the
University of Lausanne
The University of Lausanne (UNIL; ) in Lausanne, Switzerland, was founded in 1537 as a school of Protestant theology, before being made a university in 1890. The university is the second-oldest in Switzerland, and one of the oldest universities ...
and then at
Marburg
Marburg (; ) is a college town, university town in the States of Germany, German federal state () of Hesse, capital of the Marburg-Biedenkopf Districts of Germany, district (). The town area spreads along the valley of the river Lahn and has ...
. He graduated in 1904 obtaining his chemistry degree, 2 years later in 1906 he licensed for medicine and in 1908 he qualified for his
M.D.[ including the Nobel Lecture, December 11, 1930 ''On Haemin and the Relationships between Haemin and Chlorophyll''] which he applied to the University of Munich.
Career
He worked first at a Medical Clinic in
Munich
Munich is the capital and most populous city of Bavaria, Germany. As of 30 November 2024, its population was 1,604,384, making it the third-largest city in Germany after Berlin and Hamburg. Munich is the largest city in Germany that is no ...
and then at the
First Berlin Chemical Institute under
Emil Fischer
Hermann Emil Louis Fischer (; 9 October 1852 – 15 July 1919) was a German chemist and List of Nobel laureates in Chemistry, 1902 recipient of the Nobel Prize in Chemistry. He discovered the Fischer esterification. He also developed the Fisch ...
. He returned to Munich in 1911 and qualified as lecturer on internal medicine one year later. In 1913, he became a lecturer in
physiology
Physiology (; ) is the science, scientific study of function (biology), functions and mechanism (biology), mechanisms in a life, living system. As a branches of science, subdiscipline of biology, physiology focuses on how organisms, organ syst ...
at the Physiological Institute in Munich. In 1916, he became Professor of Medical Chemistry at the
University of Innsbruck
The University of Innsbruck (; ) is a public research university in Innsbruck, the capital of the Austrian federal state of Tyrol (state), Tyrol, founded on October 15, 1669.
It is the largest education facility in the Austrian States of Austria, ...
and from there he went to the
University of Vienna
The University of Vienna (, ) is a public university, public research university in Vienna, Austria. Founded by Rudolf IV, Duke of Austria, Duke Rudolph IV in 1365, it is the oldest university in the German-speaking world and among the largest ...
in 1918.
From 1921 until his death, he held the position of Professor of Organic Chemistry at the
Technical University of Munich
The Technical University of Munich (TUM or TU Munich; ) is a public research university in Munich, Bavaria, Germany. It specializes in engineering, technology, medicine, and applied and natural sciences.
Established in 1868 by King Ludwig II ...
.

Fischer's scientific work was mostly concerned with the investigation of the pigments in
blood
Blood is a body fluid in the circulatory system of humans and other vertebrates that delivers necessary substances such as nutrients and oxygen to the cells, and transports metabolic waste products away from those same cells.
Blood is com ...
,
bile
Bile (from Latin ''bilis''), also known as gall, is a yellow-green/misty green fluid produced by the liver of most vertebrates that aids the digestion of lipids in the small intestine. In humans, bile is primarily composed of water, is pro ...
, and also
chlorophyll
Chlorophyll is any of several related green pigments found in cyanobacteria and in the chloroplasts of algae and plants. Its name is derived from the Greek words (, "pale green") and (, "leaf"). Chlorophyll allows plants to absorb energy ...
in
leaves
A leaf (: leaves) is a principal appendage of the stem of a vascular plant, usually borne laterally above ground and specialized for photosynthesis. Leaves are collectively called foliage, as in "autumn foliage", while the leaves, stem, ...
, as well as with the chemistry of
pyrrole from which these pigments are derived. Of special importance was his synthesis of
bilirubin
Bilirubin (BR) (adopted from German, originally bili—bile—plus ruber—red—from Latin) is a red-orange compound that occurs in the normcomponent of the straw-yellow color in urine. Another breakdown product, stercobilin, causes the brown ...
and
haemin. He received many honors for this work, and received the
Nobel Prize
The Nobel Prizes ( ; ; ) are awards administered by the Nobel Foundation and granted in accordance with the principle of "for the greatest benefit to humankind". The prizes were first awarded in 1901, marking the fifth anniversary of Alfred N ...
in 1930. The
lunar crater Fischer was named after him (and
Hermann Emil Fischer
Hermann Emil Louis Fischer (; 9 October 1852 – 15 July 1919) was a German chemist and List of Nobel laureates in Chemistry, 1902 recipient of the Nobel Prize in Chemistry. He discovered the Fischer esterification. He also developed the Fisch ...
) in 1976. Hans Fisher had mapped the composition of a hem group. In 1929 Fischer succeeded in producing the substance and proving that its ring has a central atom of iron, as he also continued studying other pigmented substances of a biological importance of biochemistry such as chlorophyll, the color that plays part in a plants photosynthesis. Fischer also unraveled the bile pigments biliverdin (which causes the yellowish color characteristic of bruised skin) and bilirubin (which yellows skin in jaundice cases), and synthesized them in 1942 and 1944, successively. He conducted microanalyses of more than 60,000 chemical substance, and had won the Nobel Prize for Chemistry in 1930. The person that sparked Fischer's interest was von Muller, his former professor and supervisor whom interests were in pyrrole pigments by inviting Fischer to work with him at the well-known Second Medical Clinic in Munich in 1910. Under Muller, he began to examine the composition of the bile pigment bilirubin, something he would continue to be engaged in during the decades that followed. Fischer's succession also came with difficulty's as many of his experiments seemed to have failed but with time Fischer was able to perfect his acknowledgement with his failed attempts.
Personal life
Fischer married Wiltrud Haufe around his 50's in the year 1935. Fischer was a man who was dedicated almost "exclusively" to his work. He continued his scientific research during Germany's Nazi era, and committed suicide on Easter Sunday in 1945, after his laboratory and life's work had been destroyed by the bombing in the last days of World War II.
Honours
*Fellow of the
Academy of Sciences Leopoldina (1919)
*
Privy Councillor (1925)
*Liebig Memorial Medal (1929)
*
Nobel Prize for Chemistry
The Nobel Prize in Chemistry () is awarded annually by the Royal Swedish Academy of Sciences to scientists in the various fields of chemistry. It is one of the five Nobel Prizes established by the will of Alfred Nobel in 1895, awarded for outst ...
(1930)
*
Honorary doctorate
An honorary degree is an academic degree for which a university (or other degree-awarding institution) has waived all of the usual requirements. It is also known by the Latin phrases ''honoris causa'' ("for the sake of the honour") or '' ad hon ...
,
Harvard University
Harvard University is a Private university, private Ivy League research university in Cambridge, Massachusetts, United States. Founded in 1636 and named for its first benefactor, the History of the Puritans in North America, Puritan clergyma ...
(1936)
*
Davy Medal of the
Royal Society of London
The Royal Society, formally The Royal Society of London for Improving Natural Knowledge, is a learned society and the United Kingdom's national academy of sciences. The society fulfils a number of roles: promoting science and its benefits, r ...
(1937)
Literature
*
*
*
*
*
References
External links
*
* including the Nobel Lecture, December 11, 1930
{{DEFAULTSORT:Fischer, Hans
1881 births
1945 suicides
1945 deaths
German Nobel laureates
German organic chemists
20th-century German chemists
Nobel laureates in Chemistry
Scientists from Frankfurt
People from Hesse-Nassau
University of Marburg alumni
Academic staff of the University of Innsbruck
Academic staff of the University of Vienna
Academic staff of the Technical University of Munich
Suicides in Germany