HEPPS (EPPS) is a
buffering agent used in
biology and
biochemistry. The pKa of HEPPS is 8.00. It is ones of
Good's buffers.
Research on mice with
Alzheimer's disease
Alzheimer's disease (AD) is a neurodegeneration, neurodegenerative disease that usually starts slowly and progressively worsens. It is the cause of 60–70% of cases of dementia. The most common early symptom is difficulty in short-term me ...
-like
amyloid beta
Amyloid beta (Aβ or Abeta) denotes peptides of 36–43 amino acids that are the main component of the amyloid plaques found in the brains of people with Alzheimer's disease. The peptides derive from the amyloid precursor protein (APP), which is ...
plaques has shown that HEPPS can cause the plaques to break up, reversing some of the symptoms in the mice. HEPPS was reported to dissociate
amyloid beta
Amyloid beta (Aβ or Abeta) denotes peptides of 36–43 amino acids that are the main component of the amyloid plaques found in the brains of people with Alzheimer's disease. The peptides derive from the amyloid precursor protein (APP), which is ...
oligomers in patients' plasma samples enabling blood diagnosis of
Alzheimer's disease
Alzheimer's disease (AD) is a neurodegeneration, neurodegenerative disease that usually starts slowly and progressively worsens. It is the cause of 60–70% of cases of dementia. The most common early symptom is difficulty in short-term me ...
.
See also
*
CAPSO
*
CHES Ches may refer to:
* Assata Shakur (married name Joanne Chesimard), nickname
* CHES (buffer)
*William Cheswick ("Ches") a computer security and networking researcher
See also
*Chez (disambiguation)
*Chess
Chess is a board game for two playe ...
*
HEPES
References
Buffer solutions
Sulfonic acids
Piperazines
Primary alcohols
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