Berthold Carl Gustav Giemsa (; November 20, 1867 – June 10, 1948) was a German

chemist A chemist (from Greek ''chēm(ía)'' alchemy; replacing ''chymist'' from Medieval Latin ''alchemist'') is a graduated scientist trained in the study of chemistry, or an officially enrolled student in the field. Chemists study the composition of ...

and

bacteriologist A bacteriologist is a microbiologist, or similarly trained professional, in bacteriology— a subdivision of microbiology that studies bacteria, typically Pathogenic bacteria, pathogenic ones. Bacteriologists are interested in studying and learnin ...

who was a native of Medar-Blechhammer (now part of the city

Kędzierzyn-Koźle Kędzierzyn-Koźle () is a city in south-western Poland, the administrative center of Kędzierzyn-Koźle County. With 58,899 inhabitants as of 2021, it is the second most-populous city in the Opole Voivodeship. Founded from the merger of the prev ...

). He is best known for creating a dye solution commonly known as "

Giemsa stain Giemsa stain (), named after German chemist and bacteriologist Gustav Giemsa, is a nucleic acid stain used in cytogenetics and for the histopathological diagnosis of malaria and other parasites. Uses It is specific for the phosphate groups o ...

" which is used in staining for use in the

histopathological Histopathology (compound of three Greek language, Greek words: 'tissue', 'suffering', and ''-logy, -logia'' 'study of') is the light microscope, microscopic examination of Tissue (biology), tissue in order to study the manifestations of dis ...

diagnosis of

malaria Malaria is a Mosquito-borne disease, mosquito-borne infectious disease that affects vertebrates and ''Anopheles'' mosquitoes. Human malaria causes Signs and symptoms, symptoms that typically include fever, Fatigue (medical), fatigue, vomitin ...

and parasites such as ''

Plasmodium ''Plasmodium'' is a genus of unicellular eukaryotes that are obligate parasites of vertebrates and insects. The life cycles of ''Plasmodium'' species involve development in a Hematophagy, blood-feeding insect host (biology), host which then inj ...

'', ''

Trypanosoma ''Trypanosoma'' is a genus of kinetoplastids (class Trypanosomatidae), a monophyletic group of unicellular parasitic flagellate protozoa. Trypanosoma is part of the phylum Euglenozoa. The name is derived from the Ancient Greek ''trypano-'' (b ...

'', and ''

Chlamydia Chlamydia, or more specifically a chlamydia infection, is a sexually transmitted infection caused by the bacterium ''Chlamydia trachomatis''. Most people who are infected have no symptoms. When symptoms do appear, they may occur only several w ...

''.

Life and work

Giemsa was born in Blechhammer (now Blachownia Śląska, a district within the city of

) to Gustav, a mining official and Franziska. He studied

pharmacy Pharmacy is the science and practice of discovering, producing, preparing, dispensing, reviewing and monitoring medications, aiming to ensure the safe, effective, and affordable use of medication, medicines. It is a miscellaneous science as it ...

and

mineralogy Mineralogy is a subject of geology specializing in the scientific study of the chemistry, crystal structure, and physical (including optical mineralogy, optical) properties of minerals and mineralized artifact (archaeology), artifacts. Specific s ...

at the

University of Leipzig Leipzig University (), in Leipzig in Saxony, Germany, is one of the world's oldest universities and the second-oldest university (by consecutive years of existence) in Germany. The university was founded on 2 December 1409 by Frederick I, Electo ...

(1892-94), and then worked between 1895 and 1898 as a

pharmacist A pharmacist, also known as a chemist in English in the Commonwealth of Nations, Commonwealth English, is a healthcare professional who is knowledgeable about preparation, mechanism of action, clinical usage and legislation of medications in ...

at the

government hospital A public hospital, or government hospital, is a hospital which is government owned and is predominantly funded by the government and operates predominantly off the money that is collected from taxpayers to fund healthcare initiatives. In almost al ...

in Dar-es-Salaam,

German East Africa German East Africa (GEA; ) was a German colonial empire, German colony in the African Great Lakes region, which included present-day Burundi, Rwanda, the Tanzania mainland, and the Kionga Triangle, a small region later incorporated into Portugu ...

. He returned in 1898 and studied chemistry and bacteriology at the

University of Berlin The Humboldt University of Berlin (, abbreviated HU Berlin) is a public research university in the central borough of Mitte in Berlin, Germany. The university was established by Frederick William III on the initiative of Wilhelm von Humbol ...

and then became an assistant to Bernhard Nocht at the '' Institut für Tropenmedizin'' in

Hamburg Hamburg (, ; ), officially the Free and Hanseatic City of Hamburg,. is the List of cities in Germany by population, second-largest city in Germany after Berlin and List of cities in the European Union by population within city limits, 7th-lar ...

, and in 1900 became head of the Department of Chemistry. In 1904 Giemsa published an essay on the staining procedure for

flagellate A flagellate is a cell or organism with one or more whip-like appendages called flagella. The word ''flagellate'' also describes a particular construction (or level of organization) characteristic of many prokaryotes and eukaryotes and the ...

s, blood cells, and bacteria. Giemsa improved the

Romanowsky stain Romanowsky staining is a prototypical staining technique that was the forerunner of several distinct but similar stains widely used in hematology (the study of blood) and cytopathology (the study of diseased cells). Romanowsky-type stains are use ...

(

Eosin Y Eosin Y, also called C.I. 45380 or C.I. Acid Red 87, is a member of the triarylmethane dyes. It is produced from fluorescein by bromination. Use Eosin Y is commonly used as the red dye in red inks. It is commonly used in histology, most nota ...

and

Methylene Blue Methylthioninium chloride, commonly called methylene blue, is a salt used as a dye and as a medication. As a medication, it is mainly used to treat methemoglobinemia. It has previously been used for treating cyanide poisoning and urinary trac ...

) by stabilizing this dye solution with

glycerol Glycerol () is a simple triol compound. It is a colorless, odorless, sweet-tasting, viscous liquid. The glycerol backbone is found in lipids known as glycerides. It is also widely used as a sweetener in the food industry and as a humectant in pha ...

. This allowed for reproducible staining of cells for microscopy purposes. This method made rapid malaria screening feasible and is still used in laboratories today. In 1933 Giemsa signed the ''

Vow of allegiance of the Professors of the German Universities and High-Schools to Adolf Hitler and the National Socialistic State officially translated into English as the Vow of allegiance of the Professors of the German Universities and High-Schools to Adolf Hitler and the National Socialistic State was a document presented on 11 November 1933 at the Albert Hall in Leipzi ...

''. He also joined the

NSDAP The Nazi Party, officially the National Socialist German Workers' Party ( or NSDAP), was a far-right political party in Germany active between 1920 and 1945 that created and supported the ideology of Nazism. Its precursor, the German Workers ...

References

Other sources

Ernst Klee Ernst Klee (15 March 1942, Frankfurt – 18 May 2013, Frankfurt) was a German journalist and author. As a writer on Germany's history, he was best known for his exposure and documentation of medical crimes in Nazi Germany, much of which was conce ...

: Das Personenlexikon zum Dritten Reich. Wer war was vor und nach 1945. Fischer Taschenbuch Verlag, Zweite aktualisierte Auflage, Frankfurt am Main 2005, S. 182. * Fleischer B. Editorial
100 years ago: Giemsa's solution for staining of plasmodia
Trop Med Int Health. 2004 Jul;9(7):755-6.

External links

* {{DEFAULTSORT:Giemsa, Gustav 1867 births 1948 deaths 19th-century German chemists German microbiologists Nazi Party members Scientists from the Province of Silesia Leipzig University alumni Humboldt University of Berlin alumni 20th-century German chemists People from Kędzierzyn-Koźle