Gustav Giemsa (; November 20, 1867 – June 10, 1948) was a German

chemist A chemist (from Greek ''chēm(ía)'' alchemy; replacing ''chymist'' from Medieval Latin ''alchemist'') is a scientist trained in the study of chemistry. Chemists study the composition of matter and its properties. Chemists carefully describe ...

and

bacteriologist A bacteriologist is a microbiologist, or similarly trained professional, in bacteriology -- a subdivision of microbiology that studies bacteria, typically pathogenic ones. Bacteriologists are interested in studying and learning about bacteria, as ...

who was a native of Medar-Blechhammer (now part of the city

Kędzierzyn-Koźle Kędzierzyn-Koźle (german: Kandrzin-Cosel, szl, Kandrzin-Koźle) is a city in southern Poland, the administrative center of Kędzierzyn-Koźle County. With 58,899 inhabitants as of 2021, it is the second most-populous city in the Opole Voivode ...

). He is remembered for creating a dye solution commonly known as "

Giemsa stain Giemsa stain (), named after German chemist and bacteriologist Gustav Giemsa, is a nucleic acid stain used in cytogenetics and for the histopathological diagnosis of malaria and other parasites. Uses It is specific for the phosphate groups of ...

". This dye is used for the

histopathological Histopathology (compound of three Greek words: ''histos'' "tissue", πάθος ''pathos'' "suffering", and -λογία ''-logia'' "study of") refers to the microscopic examination of tissue in order to study the manifestations of disease. Spec ...

diagnosis of

malaria Malaria is a mosquito-borne infectious disease that affects humans and other animals. Malaria causes symptoms that typically include fever, tiredness, vomiting, and headaches. In severe cases, it can cause jaundice, seizures, coma, or deat ...

and parasites such as ''

Plasmodium ''Plasmodium'' is a genus of unicellular eukaryotes that are obligate parasites of vertebrates and insects. The life cycles of ''Plasmodium'' species involve development in a blood-feeding insect host which then injects parasites into a vert ...

'', ''

Trypanosoma ''Trypanosoma'' is a genus of kinetoplastids (class Trypanosomatidae), a monophyletic group of unicellular parasitic flagellate protozoa. Trypanosoma is part of the phylum Sarcomastigophora. The name is derived from the Greek ''trypano-'' (b ...

'', and ''

Chlamydia Chlamydia, or more specifically a chlamydia infection, is a sexually transmitted infection caused by the bacterium '' Chlamydia trachomatis''. Most people who are infected have no symptoms. When symptoms do appear they may occur only several w ...

''. Giemsa studied

pharmacy Pharmacy is the science and practice of discovering, producing, preparing, dispensing, reviewing and monitoring medications, aiming to ensure the safe, effective, and affordable use of medication, medicines. It is a miscellaneous science as it ...

and

mineralogy Mineralogy is a subject of geology specializing in the scientific study of the chemistry, crystal structure, and physical (including optical) properties of minerals and mineralized artifacts. Specific studies within mineralogy include the proce ...

at the

University of Leipzig Leipzig University (german: Universität Leipzig), in Leipzig in Saxony, Germany, is one of the world's oldest universities and the second-oldest university (by consecutive years of existence) in Germany. The university was founded on 2 Decemb ...

, and chemistry and bacteriology at the

University of Berlin The Humboldt University of Berlin (german: link=no, Humboldt-Universität zu Berlin, abbreviated HU Berlin) is a public research university in the central borough of Mitte in Berlin, Germany. The university was established by Frederick Will ...

. Between 1895 and 1898 he worked as a

pharmacist A pharmacist, also known as a chemist (Commonwealth English) or a druggist (North American and, archaically, Commonwealth English), is a healthcare professional who prepares, controls and distributes medicines and provides advice and instructi ...

German East Africa German East Africa (GEA; german: Deutsch-Ostafrika) was a German colony in the African Great Lakes region, which included present-day Burundi, Rwanda, the Tanzania mainland, and the Kionga Triangle, a small region later incorporated into Mo ...

. He was an early assistant to Bernhard Nocht at the '' Institut für Tropenmedizin'' in

Hamburg Hamburg (, ; nds, label=Hamburg German, Low Saxon, Hamborg ), officially the Free and Hanseatic City of Hamburg (german: Freie und Hansestadt Hamburg; nds, label=Low Saxon, Friee un Hansestadt Hamborg),. is the List of cities in Germany by popul ...

, where in 1900 he became head of the Department of Chemistry. In 1904 Giemsa published an essay on the staining procedure for

flagellate A flagellate is a cell or organism with one or more whip-like appendages called flagella. The word ''flagellate'' also describes a particular construction (or level of organization) characteristic of many prokaryotes and eukaryotes and the ...

s, blood cells, and bacteria. Giemsa improved the

Romanowsky stain Romanowsky staining, also known as Romanowsky–Giemsa staining, is a prototypical staining (biology), staining technique that was the forerunner of several distinct but similar stains widely used in hematology (the study of blood) and cytopathol ...

(

Eosin Y Eosin Y, also called C.I. 45380 or C.I. Acid Red 87, is a member of the triarylmethane dyes. It is produced from fluorescein by bromination. Use Eosin Y is commonly used as the red dye in red inks. It is commonly used in histology, most notab ...

and

Methylene Blue Methylthioninium chloride, commonly called methylene blue, is a salt used as a dye and as a medication. Methylene blue is a thiazine dye. As a medication, it is mainly used to treat methemoglobinemia by converting the ferric iron in hemoglob ...

) by stabilizing this dye solution with

glycerol Glycerol (), also called glycerine in British English and glycerin in American English, is a simple triol compound. It is a colorless, odorless, viscous liquid that is sweet-tasting and non-toxic. The glycerol backbone is found in lipids know ...

. This allowed for reproducible staining of cells for microscopy purposes. This method is still used in laboratories today. In 1933 Giemsa signed the '' Vow of allegiance of the Professors of the German Universities and High-Schools to Adolf Hitler and the National Socialistic State''. He also joined the

NSDAP The Nazi Party, officially the National Socialist German Workers' Party (german: Nationalsozialistische Deutsche Arbeiterpartei or NSDAP), was a far-right politics, far-right political party in Germany active between 1920 and 1945 that crea ...

References

Ernst Klee Ernst Klee (15 March 1942, Frankfurt – 18 May 2013, Frankfurt) was a German journalist and author. As a writer on Germany's history, he was best known for his exposure and documentation of medical crimes in Nazi Germany, much of which was concer ...

: Das Personenlexikon zum Dritten Reich. Wer war was vor und nach 1945. Fischer Taschenbuch Verlag, Zweite aktualisierte Auflage, Frankfurt am Main 2005, S. 182. * Fleischer B. Editorial
100 years ago: Giemsa's solution for staining of plasmodia
Trop Med Int Health. 2004 Jul;9(7):755-6.

External links

* {{DEFAULTSORT:Giemsa, Gustav 1867 births 1948 deaths 19th-century German chemists German microbiologists Nazi Party members People from the Province of Silesia Leipzig University alumni Humboldt University of Berlin alumni 20th-century German chemists