Guo Mei
   HOME

TheInfoList



OR:

Guo Mei (, born January, 1968) is a hematologist and associate director of 307th Hospital of Chinese People’s Liberation Army and deputy director of Radiation Research Institute. Guo Mei is a Chinese
physician A physician, medical practitioner (British English), medical doctor, or simply doctor is a health professional who practices medicine, which is concerned with promoting, maintaining or restoring health through the Medical education, study, Med ...
who works with Huisheng Ai. She graduated from
Academy of Military Medical Sciences The Academy of Military Medical Sciences (AMMS) of the People's Liberation Army Academy of Military Sciences () is a Chinese military medical research institute. It was established in Shanghai in 1951. It has been based in Beijing since 1958. In ...
and got
master degree A master's degree (from Latin ) is a postgraduate academic degree awarded by universities or colleges upon completion of a course of study demonstrating mastery or a high-order overview of a specific field of study or area of professional practi ...
in 1997. She is a pre-eminent expert in the use of
hematopoietic stem cell transplantation Hematopoietic stem-cell transplantation (HSCT) is the transplantation of multipotent hematopoietic stem cells, usually derived from bone marrow, peripheral blood, or umbilical cord blood, in order to replicate inside a patient and produce ...
for treating radiation injuries and
blood disease Hematology (American and British English spelling differences#ae and oe, spelled haematology in British English) is the branch of medicine concerned with the study of the cause, prognosis, treatment, and prevention of diseases related to bloo ...
, especially leukemia,
aplastic anemia Aplastic anemia (AA) is a severe hematologic condition in which the body fails to make blood cells in sufficient numbers. Normally, blood cells are produced in the bone marrow by stem cells that reside there, but patients with aplastic anemia ...
and
myelodysplastic syndrome A myelodysplastic syndrome (MDS) is one of a group of cancers in which blood cells in the bone marrow do not mature, and as a result, do not develop into healthy blood cells. Early on, no symptoms typically are seen. Later, symptoms may includ ...
. She is one of the founders of microtransplantation. Years of education and research experience in microtransplantation have earned her a large amount of respect from her colleagues. Her expertise is reflected in the awards and recognition she has received. Guo Mei brings her passion and knowledge for treating blood disease with microtransplantation in 307th Hospital, and with an equally dedicated medical and support team, works hard every day to improve the quality of lives of the patients.


Research

1998 Dr. Guo and her medical team developed "Study of HLA-matched nonmyeloablative transplantation in the treatment of hematological malignancies" successfully. 2004 The study of HLA haploidentical blood related and unrelated matched donors nonmyeloablative transplantation for the treatment of blood diseases. 2005 Treatment of Jining serious radiation accidents and extremely severe bone marrow and intestinal radiation 2006 Developed an original creativity of microtransplantation for the treatment of leukemia. This technology opens up new opportunities for treating leukemia in world. From 2010 to 2015, she took part in 12 projects of national 863 and provincial projects. As the first applicants, she took five scientific research projects, including the National Ministry of science and Technology Department project, National 11th Five-Year Plan key project of scientific and technological and National 12th Five-Year Plan key project of scientific and technological.


Honours

*First prize of military medical achievement award in June 2005 *Military medical achievement award in March 2006 *Second prize of military medical achievement award in September 2007 *Honourable title of the 3rd merit in 2008 Her accomplishments include over 100 published research articles, including four articles that have been recorded by SCI ('' JCO'': 18.4, ''
Blood Blood is a body fluid in the circulatory system of humans and other vertebrates that delivers necessary substances such as nutrients and oxygen to the cells, and transports metabolic waste products away from those same cells. Blood is com ...
'': 10.55, ''BBMT'' 3.86)
aplastic anemia Aplastic anemia (AA) is a severe hematologic condition in which the body fails to make blood cells in sufficient numbers. Normally, blood cells are produced in the bone marrow by stem cells that reside there, but patients with aplastic anemia ...
and
myelodysplastic syndrome A myelodysplastic syndrome (MDS) is one of a group of cancers in which blood cells in the bone marrow do not mature, and as a result, do not develop into healthy blood cells. Early on, no symptoms typically are seen. Later, symptoms may includ ...
.Cotransplant of HLA haploidentical peripehral blood stem cells and mesenchymal stem cells to treat a child with severe aplastic anemia, Chinese Journal of Hematology 2012 Vol. 33 (3): 242-242.
/ref> She has co-authored five monographs, including "Hematopoietic stem cell transplantation clinical and basic," "Modern leukemia study," "Clinical and basic research of radiation sickness," and two more books.


Academic papers

* 2011
Infusion of HLA-mismatched peripheral blood stem cells improves the outcome of chemotherapy for acute myeloid leukemia in elderly patients
, published in ''
Blood Blood is a body fluid in the circulatory system of humans and other vertebrates that delivers necessary substances such as nutrients and oxygen to the cells, and transports metabolic waste products away from those same cells. Blood is com ...
'' * 2012
HLA-Mismatched Stem-Cell Microtransplantation as Postremission Therapy for Acute Myeloid Leukemia: Long-Term Follow-Up
in ''
J Clin Oncol The ''Journal of Clinical Oncology'' is a peer-reviewed medical journal published 3 times a month by ASCO Publications. It covers research on all aspects of clinical oncology. The journal was established in 1983 and the editor-in-chief is Jonatha ...
'' * 2015
Efficacy of Switching to 2nd Generation of Tyrosine Kinase Inhibitor on CML Patients at Poor Responses to Imatinib
* 2014
Comparison of conditioning regimens containing or no fludarabine in nonmyeloablative allogeneic peripheral blood stem cell transplantation
* 2014
The Existence and Role of Microchimerism after Microtransplantion
' *2014
Malposition of peripherally inserted central catheter: experience from 3012 cancer patients
' *2014
Establishment and identification of a h-2 completely mismatched microtransplantation model of leukemia mouse
' * 2013
Abnormality of blood coagulation indexes in patients with de novo acute leukemia and its clinical significance
' * 2014
Risk factors analysis of cytomegalovirus infection after nonmyeloablative allogeneic peripheral blood stem cell transplantation
'' * 2014
Severe acute radiation syndrome: treatment of a lethally 60Co-source irradiated accident victim in China with HLA-mismatched peripheral blood stem cell transplantation and mesenchymal stem cells
' * 2013
Haploidentical nonmyeloablative allogeneic peripheral blood stem cell transplantation for treatment of refractory or relapsed leukemia: long-term follow-up
' * 2013
Changes of Th1/Th2/Th17 in patients received non-myeloablative haploidentical hematopoietic stem cell transplantation detected by flow cytometric bead array
' *2013
Different changes of serum cytokines following HLA-identical and HLA haploidentical non-myeloablative allogeneic hematopoietic stem cell transplantation
' * 2013
Clinical investigation of refractory lymphoma with HLA-mismatched stem-cell microtransplantation
' *2011
Role of G-CSF in the proliferation, differentiation and cell cycle distribution of mouse thymocytes after acute radiation
' *2011
CM-DiI labeled mesenchymal stem cells homed to thymus inducing immune recovery of mice after haploidentical bone marrow transplantation
, published on ''Int Immunopharmacol.'' *2011
Expression of NOV and BNIP3 gene in mouse myelomonocytic leukemia and its significance
' *2011
Relationship between WT1-specific T-cell subsets and graft-versus-host disease after nonmyeloablative allogeneic transplantation
' *2011
WT1-specific CTL cells of recipient origin may exist in the peripheral blood of patients achieving full donor chimerism soon after nonmyeloablative transplantation
, published on ''Clin Transplant.'' * 2010
Application of HLA-A*0201/WT1 pentamer combined with intracellular IFNgamma+ staining in detecting circulating WT1 specific T cells in leukemia
' *2010
Comparison of Wilms' tumor antigen 1-specific T lymphocyte generation soon after nonmyeloablative allergenic stem-cell transplantation in acute and chronic leukemia patients
, published in ''Int J Hematol.'' * 2009
Changes of lymphocyte subsets in acute leukemia patients after HLA-mismatched nonmyeloablative hematopoietic stem cell transplantation
' * 2010
Efficacy of bone marrow-derived mesenchymal stem cells in the treatment of sclerodermatous chronic graft-versus-host disease: clinical report
, published in ''Biol Blood Marrow Transplant'' *2009
A modified haploidentical nonmyeloablative transplantation without T cell depletion for high-risk acute leukemia: successful engraftment and mild GVHD
published in ''Biol Blood Marrow Transplant.'' *2008
Acute graft versus host disease in non-myeloablative allogeneic stem cell transplantation
' *2007
Effects of mesenchymal stem cells on cell cycle and apoptosis of hematopoietic tissue cells in irradiated mice
' * 2007
Effect of bone marrow mesenchymal stem cells on immunoregulation in H-2 haploidentical bone marrow transplantation mice
' *2007
Comparison of efficiencies mobilizing stem cells into peripheral blood in healthy donors by different schemes with G-CSF
' *2006
Ex vivo expansion and in vivo infusion of bone marrow-derived Flk-1+CD31-CD34- mesenchymal stem cells: feasibility and safety from monkey to human
, published in ''Stem Cells Dev.'' *2006
Kinetic study of various cytokine mRNA expressions in rhesus treated with haploidentical peripheral blood stem cell transplantation
' *2005
Establishment of a rhesus haploidentical hematopoietic stem cell and mesenchymal stem cell transplantation model by nonmyeloablative conditioning
' *2005
Establishment and application of a method for assessing hemopoietic chimerism in rhesus after allogeneic stem cell transplantation
' *2005
Establishment of rhesus model for haploidentical hematopoietic stem cell transplantation with nonmyeloablative conditioning
, published in ''Zhongguo Shi Yan Xue Ye Xue Za Zhi'' * 2005
Study on biological characteristics of cultured rhesus mesenchymal stem cells
' *2003
Comparison of conditioning regimens containing or no fludarabine in nonmyeloablative allogeneic peripheral blood stem cell transplantation
' *2003
Clinical significance of formation and conversion of hematopoietic mixed chimerism in nonmyeloablative allogeneic stem cell transplantation
' *2003
The clinical research of nonmyeloablative allogeneic peripheral blood hematopoietic stem cells transplantation for hematological diseases
' *2001
Nonmyeloablative Allogeneic Peripheral Blood Hematopoietic Stem Cell Transplantation for Therapy of Hematologic Diseases
' *2012
Estimation of the biological dose received by five victims of a radiation accident using three different cytogenetic tools
' *2012
HLA-Mismatched Stem-Cell Microtransplantation As Postremission Therapy for Acute Myeloid Leukemia: Long-Term Follow-Up
' *2012
Effects of IAT and MAT chemotherapeutic regimens in patients with refractory or relapsed acute myeloid leukemia
' * 2012
Effective modulation of CD4CD25 regulatory T and NK cells in malignant patients by combination of interferon-α and interleukin-2
' *2012
Clinical study of bortezomib for treating multiple myeloma with renal impairment
' *201
Clinical analysis of invastive fungal infections in patients with hematologic malignancies
* 201


References


External links

* http://www.307hospital.com/logo.jhtml * http://www.mstleukemiaclinic.com/index.html * http://www.mstleukemiaclinic.com/About_MST/Medical_Experts/Medical_Experts/55.html * http://www.newcelltech.com/a/yxal/kfbl/ {{DEFAULTSORT:Guo, Mei Living people Chinese hematologists Chilean women physicians 1968 births 20th-century Chinese physicians 21st-century Chinese physicians 20th-century Chinese women physicians 21st-century Chinese women physicians 21st-century Chinese science writers