Fritiof Gunnar Blix (7 September 1894 in Lund – 10 June 1981 in

Uppsala Uppsala ( ; ; archaically spelled ''Upsala'') is the capital of Uppsala County and the List of urban areas in Sweden by population, fourth-largest city in Sweden, after Stockholm, Gothenburg, and Malmö. It had 177,074 inhabitants in 2019. Loc ...

) was a Swedish

chemist A chemist (from Greek ''chēm(ía)'' alchemy; replacing ''chymist'' from Medieval Latin ''alchemist'') is a graduated scientist trained in the study of chemistry, or an officially enrolled student in the field. Chemists study the composition of ...

and Professor of Medical and

Physiological chemistry Biochemistry, or biological chemistry, is the study of chemical processes within and relating to living organisms. A sub-discipline of both chemistry and biology, biochemistry may be divided into three fields: structural biology, enzymology, a ...

at the

University of Uppsala Uppsala University (UU) () is a public research university in Uppsala, Sweden. Founded in 1477, it is the oldest university in Sweden and the Nordic countries still in operation. Initially founded in the 15th century, the university rose to s ...

. He was the son of professor

Magnus Blix Magnus Gustaf Blix (25 December 1849 – 14 February 1904) was a Swedish physiologist born in the parish Säbrå, presently located in Härnösand Municipality. He is the grandfather of UN weapons inspector Hans Blix. During his career he was a p ...

, father of politician

Hans Blix Hans Martin Blix (; born 28 June 1928) is a Swedish diplomat and politician for the Liberal People's Party. He was Swedish Minister for Foreign Affairs (1978–1979) and later became the head of the International Atomic Energy Agency. Blix wa ...

, and grandfather of journalist . Blix graduated from the

Cathedral School Cathedral schools began in the Early Middle Ages as centers of advanced education, some of them ultimately evolving into medieval universities. Throughout the Middle Ages and beyond, they were complemented by the monastic schools. Some of these ...

in central

Lund Lund (, ;"Lund"
(US) and ) is a city in the provinces of Sweden, province of Scania, southern Swed ...

in 1912. He began his medical studies at

Lund University Lund University () is a Public university, public research university in Sweden and one of Northern Europe's oldest universities. The university is located in the city of Lund in the Swedish province of Scania. The university was officially foun ...

in 1912 and became a medical student in 1916, received a license to practice medicine in 1922, and earned his PhD in 1925. He started working in the laboratory of Physical Chemistry at Uppsala University in 1925 and served as a Professor of Medical and Physiological Chemistry there from 1930 to 1961. Blix was a member of several boards of inquiry (similar to a

Royal Commission A royal commission is a major ad-hoc formal public inquiry into a defined issue in some monarchies. They have been held in the United Kingdom, Australia, Canada, New Zealand, Norway, Malaysia, Mauritius and Saudi Arabia. In republics an equi ...

) including the 1958 investigation at the Medical College in

Umeå Umeå ( , , , locally ; ; ; ; ) is a city in northeast Sweden. It is the seat of Umeå Municipality and the capital of Västerbotten County. Situated on the Ume River, Umeå is the largest Urban areas in Sweden, locality in Norrland and the t ...

. Blix was also a member of the

Royal Society of Sciences in Uppsala The Royal Society of Sciences in Uppsala (), is the oldest of the royal academies in Sweden, having been founded in 1710. The society has, by royal decree of 1906, 50 Swedish fellows and 100 foreign. Early members included Emanuel Swedenborg an ...

. In 1950 he became an honorary member of the Austrian Society for Analytical Chemistry (ASAC). Blix also served as

Prorector Academic rank (also scientific rank) is the rank of a scientist or teacher in a college, high school, university or research establishment. The academic ranks indicate relative importance and power of individuals in academia. The academic ran ...

at the University of Uppsala from 1956-1961. Blix's research focused on

physiological chemistry Biochemistry, or biological chemistry, is the study of chemical processes within and relating to living organisms. A sub-discipline of both chemistry and biology, biochemistry may be divided into three fields: structural biology, enzymology, a ...

and nutrition research. Much of his early work involved fats chemistry. His thesis concerned the

blood lipids Blood lipids (or blood fats) are lipids in the blood, either free or bound to other molecules. They are mostly transported in a phospholipid capsule, and the type of protein embedded in this outer shell determines the fate of the particle and its ...

diabetic Diabetes mellitus, commonly known as diabetes, is a group of common endocrine diseases characterized by sustained high blood sugar levels. Diabetes is due to either the pancreas not producing enough of the hormone insulin, or the cells of th ...

s. In 1933 he discovered that sulfatide in the brain contained amide-bound fatty acid and 4-sphingenine. Along with Arne Tiselius and Harry Svensson he discovered lipoproteins in 1941 - a fundamental discovery for research on

atherosclerosis Atherosclerosis is a pattern of the disease arteriosclerosis, characterized by development of abnormalities called lesions in walls of arteries. This is a chronic inflammatory disease involving many different cell types and is driven by eleva ...

. He also conducted extensive studies of

hyaluronan Hyaluronic acid (; abbreviated HA; conjugate acid, conjugate base hyaluronate), also called hyaluronan, is an anion#Anions and cations, anionic, Sulfation, nonsulfated glycosaminoglycan distributed widely throughout connective tissue, connective ...

(

hyaluronic acid Hyaluronic acid (; abbreviated HA; conjugate base hyaluronate), also called hyaluronan, is an anionic, nonsulfated glycosaminoglycan distributed widely throughout connective, epithelial, and neural tissues. It is unique among glycosaminog ...

). He discovered and named

sialic acid Sialic acids are a class of alpha-keto acid sugars with a nine-carbon backbone. The term "sialic acid" () was first introduced by Swedish biochemist Gunnar Blix in 1952. The most common member of this group is ''N''-acetylneuraminic acid ...

s in 1952. Blix was elected in 1956 as Member of the

Royal Swedish Academy of Sciences The Royal Swedish Academy of Sciences () is one of the Swedish Royal Academies, royal academies of Sweden. Founded on 2 June 1739, it is an independent, non-governmental scientific organization that takes special responsibility for promoting nat ...

. He is buried in Uppsala old cemetery.

References

1894 births 1981 deaths Members of the Royal Swedish Academy of Sciences People from Lund Swedish chemists Academic staff of Uppsala University Burials at Uppsala old cemetery {{chemist-stub