Gunnar B. Stickler
   HOME

TheInfoList



OR:

Gunnar B. Stickler (13 June 1925 – 4 November 2010) was a
pediatrician Pediatrics (American English) also spelled paediatrics (British English), is the branch of medicine that involves the medical care of infants, children, adolescents, and young adults. In the United Kingdom, pediatrics covers many of their youth ...
who made substantial contributions to the field of
pediatrics Pediatrics (American English) also spelled paediatrics (British English), is the branch of medicine that involves the medical care of infants, children, Adolescence, adolescents, and young adults. In the United Kingdom, pediatrics covers many o ...
. He was the first scientist to describe a hereditary condition now known as
Stickler syndrome Stickler syndrome (hereditary progressive arthro-ophthalmodystrophy) is a group of rare genetic disorders affecting connective tissue, specifically collagen. Stickler syndrome is a subtype of collagenopathy, types II and XI. Stickler syndrome i ...
.


Early life

Gunnar B. Stickler was born June 13, 1925, in Peterskirchen,
Germany Germany, officially the Federal Republic of Germany, is a country in Central Europe. It lies between the Baltic Sea and the North Sea to the north and the Alps to the south. Its sixteen States of Germany, constituent states have a total popu ...
and died on November 4, 2010, in
Minneapolis Minneapolis is a city in Hennepin County, Minnesota, United States, and its county seat. With a population of 429,954 as of the 2020 United States census, 2020 census, it is the state's List of cities in Minnesota, most populous city. Locat ...
, Minnesota, US. He attended the
Wilhelmsgymnasium (Munich) The Wilhelmsgymnasium is a Gymnasium (Germany), gymnasium (selective school) in Munich, Germany. Founded in 1559 to educate local boys, it is now coeducational. Wilhelmsgymnasium is one of the few remaining gymnasiums in Bavaria to be a "pure ''H ...
, Germany. Beginning in 1944, he studied
medicine Medicine is the science and Praxis (process), practice of caring for patients, managing the Medical diagnosis, diagnosis, prognosis, Preventive medicine, prevention, therapy, treatment, Palliative care, palliation of their injury or disease, ...
at the universities of
Vienna Vienna ( ; ; ) is the capital city, capital, List of largest cities in Austria, most populous city, and one of Federal states of Austria, nine federal states of Austria. It is Austria's primate city, with just over two million inhabitants. ...
,
Erlangen Erlangen (; , ) is a Middle Franconian city in Bavaria, Germany. It is the seat of the administrative district Erlangen-Höchstadt (former administrative district Erlangen), and with 119,810 inhabitants (as of 30 September 2024), it is the smalle ...
and
Munich Munich is the capital and most populous city of Bavaria, Germany. As of 30 November 2024, its population was 1,604,384, making it the third-largest city in Germany after Berlin and Hamburg. Munich is the largest city in Germany that is no ...
. After graduation in 1949, he spent one year in clinical
pathology Pathology is the study of disease. The word ''pathology'' also refers to the study of disease in general, incorporating a wide range of biology research fields and medical practices. However, when used in the context of modern medical treatme ...
and one in pathologic
anatomy Anatomy () is the branch of morphology concerned with the study of the internal structure of organisms and their parts. Anatomy is a branch of natural science that deals with the structural organization of living things. It is an old scien ...
in Munich. In 1951 he emigrated to the US after being accepted for an internship at the
Mountainside Hospital Hackensack Meridian Health Mountainside Medical Center, also known as Mountainside Hospital, is an acute-care hospital located in Glen Ridge, New Jersey, United States. The hospital has 365 beds and serves Northern Essex County. A part of the H ...
,
Montclair, New Jersey Montclair is a Township (New Jersey), township in Essex County, New Jersey, Essex County in the U.S. state of New Jersey. Situated on the cliffs of the Watchung Mountains, Montclair is a commercial and cultural hub of North Jersey and a diverse ...
, and subsequently for a fellowship in pediatrics at the
Mayo Clinic Mayo Clinic () is a Nonprofit organization, private American Academic health science centre, academic Medical centers in the United States, medical center focused on integrated health care, healthcare, Mayo Clinic College of Medicine and Science ...
.


Career

From 1953-56 he was a senior
cancer Cancer is a group of diseases involving Cell growth#Disorders, abnormal cell growth with the potential to Invasion (cancer), invade or Metastasis, spread to other parts of the body. These contrast with benign tumors, which do not spread. Po ...
research scientist at
Roswell Park Comprehensive Cancer Center Roswell Park Comprehensive Cancer Center is a cancer research and treatment center located in Buffalo, New York. Founded by surgeon Roswell Park in 1898, the center was the first in the United States to specifically focus on cancer research. Th ...
in Buffalo, New York. In July 1958, he was appointed to the Staff of the Mayo Clinic in pediatrics. He was elected to the
Society for Pediatric Research A society () is a group of individuals involved in persistent social interaction or a large social group sharing the same spatial or social territory, typically subject to the same political authority and dominant cultural expectations. ...
in 1962; he later served as the President of the Midwest Society for Pediatric Research. In 1967 he was named an official examiner of the
American Board of Pediatrics American(s) may refer to: * American, something of, from, or related to the United States of America, commonly known as the "United States" or "America" ** Americans, citizens and nationals of the United States of America ** American ancestry, p ...
. He advanced in academic rank to Professor of Pediatrics in 1969; in November 1969 he was named Chair of the Section of Pediatrics. The Section was later named the Department of Pediatrics under Doctor Stickler's leadership in 1974 when Mayo Clinic combined the Sections of Pediatrics and Pediatric Cardiology, when the Chair of the Section of Pediatric Cardiology James DuShane retired. Under his leadership, the Department pursued the establishment a neonatal intensive care unit and an adolescent unit at Saint Marys Hospital as well as clerkships in the new
Mayo Medical School The Mayo Clinic Alix School of Medicine (MCASOM), formerly known as Mayo Medical School (MMS), is a research-oriented medical school based in Rochester, Minnesota, with additional campuses in Arizona and Florida. MCASOM is a school within the May ...
. Doctor Stickler served on the Admissions Committee and the Medical School Coordinators Committee. Doctor Stickler also advanced primary pediatric care at Mayo Clinic as well as developed the subspecialty practices and pediatric research efforts at Mayo Clinic. He completed his term as Chair of the Department on March 31, 1980, and retired in the fall of 1989. He died unexpectedly at home from a stroke on November 4, 2010.


Stickler Syndrome

In 1960, a twelve-year-old boy was examined at a Crippled Children Clinic in
Faribault, Minnesota Faribault ( ) is a city in and the county seat of Rice County, Minnesota, United States. The population was 24,453 at the 2020 census. Faribault is approximately south of Minneapolis–Saint Paul. Interstate 35 and Minnesota State Highwa ...
, which at the time was staffed by members of the Mayo Clinic. The boy had bony enlargements of several joints and was extremely short sighted. His mother was totally blind. Dr Stickler discovered that there were other members of the family with similar
symptoms Signs and symptoms are diagnostic indications of an illness, injury, or condition. Signs are objective and externally observable; symptoms are a person's reported subjective experiences. A sign for example may be a higher or lower temperature ...
. This prompted him to study the family. With colleagues he collaborated to define the condition, the results were published in June 1965. He tentatively named the condition hereditary progressive arthro-ophthalmopathy. Since the 1980s, this condition has become to be known as
Stickler syndrome Stickler syndrome (hereditary progressive arthro-ophthalmodystrophy) is a group of rare genetic disorders affecting connective tissue, specifically collagen. Stickler syndrome is a subtype of collagenopathy, types II and XI. Stickler syndrome i ...
. Throughout the years that followed he worked with patient-support groups such as the U.S. support group
Stickler Involved People
to help improve awareness of the syndrome and the need for early and expert intervention.


Other Accomplishments

Besides the landmark paper on hereditary progressive arthro-ophthalmopathy he has authored or co-authored some 200 scientific papers. He published a landmark paper published in ''Pediatrics'' in 1965 with Edward O'Connell and Robert Feldt on the importance of small head circumference and its association with mental retardation and short stature. He conducted a number of treatment trials of otitis media; this body of work eventually resulted in four publications and represented the first controlled treatment trial of otitis media in the United States. He has published extensively on pediatric nephrology, his chosen sub-speciality, and as well as a range of other pediatric problems from
cyclic vomiting syndrome Cyclic vomiting syndrome (CVS) is a chronic functional condition of unknown pathogenesis. CVS is characterized as recurring episodes lasting a single day to multiple weeks. Each episode is divided into four phases: inter-episodic, prodrome, ...
to parental worries.Stickler GB, Salter M, Broughton DD, Alario A. Parents' worries about children compared to actual risks. Clin Pediatr (Phila) 1991;30(9):522-8


References

{{DEFAULTSORT:Stickler, Gunnar B. 1925 births 2010 deaths American pediatricians German pediatricians American medical researchers German medical researchers Emigrants from West Germany to the United States People educated at the Wilhelmsgymnasium (Munich)