Guice is a surname. Notable people with the surname include: * Daniel Guice (1924–2017), American lawyer and politician * Daniel Guice Jr. (born 1953), American businessman and politician * Derrius Guice (born 1997), American football player * Jackson Guice (1961–2025), American comics artist * Jeffrey Guice (born 1959), American politician * John Guice (born 1983), Canadian football player * John T. Guice (1923–2001), United States Air Force officer * Les Guice (born 1954), American university president

See also