The Grundmann aldehyde synthesis is a
chemical reaction
A chemical reaction is a process that leads to the chemistry, chemical transformation of one set of chemical substances to another. When chemical reactions occur, the atoms are rearranged and the reaction is accompanied by an Gibbs free energy, ...
that produces an
aldehyde
In organic chemistry, an aldehyde () (lat. ''al''cohol ''dehyd''rogenatum, dehydrogenated alcohol) is an organic compound containing a functional group with the structure . The functional group itself (without the "R" side chain) can be referred ...
from an
acyl halide
An acyl halide (also known as an acid halide) is a chemical compound derived from an oxoacid by replacing a hydroxyl group () with a halide group (, where X is a halogen).
In organic chemistry, the term typically refers to acyl halides of carbox ...
.
Because of the
Rosenmund reduction
The Rosenmund reduction is a hydrogenation process in which an acyl chloride is selectively reduced to an aldehyde. The reaction was named after Karl Wilhelm Rosenmund, who first reported it in 1918.
The reaction, a hydrogenolysis, is cataly ...
and
DIBAL-H accomplish similar transformations, this reaction sequence is not practiced much currently.
References
Name reactions
Organic redox reactions
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