
The Great Plague of Marseille, also known as the Plague of Provence, was the last major outbreak of
bubonic plague
Bubonic plague is one of three types of Plague (disease), plague caused by the Bacteria, bacterium ''Yersinia pestis''. One to seven days after exposure to the bacteria, flu-like symptoms develop. These symptoms include fever, headaches, and ...
in
Western Europe
Western Europe is the western region of Europe. The region's extent varies depending on context.
The concept of "the West" appeared in Europe in juxtaposition to "the East" and originally applied to the Western half of the ancient Mediterranean ...
. Arriving in
Marseille
Marseille (; ; see #Name, below) is a city in southern France, the Prefectures in France, prefecture of the Departments of France, department of Bouches-du-Rhône and of the Provence-Alpes-Côte d'Azur Regions of France, region. Situated in the ...
,
France
France, officially the French Republic, is a country located primarily in Western Europe. Overseas France, Its overseas regions and territories include French Guiana in South America, Saint Pierre and Miquelon in the Atlantic Ocean#North Atlan ...
, in 1720, the disease killed over 100,000 people: 50,000 in the city during the next two years and another 50,000 to the north in surrounding provinces and towns.
While economic activity took only a few years to recover, as trade expanded to the
West Indies
The West Indies is an island subregion of the Americas, surrounded by the Atlantic Ocean, North Atlantic Ocean and the Caribbean Sea, which comprises 13 independent island country, island countries and 19 dependent territory, dependencies in thr ...
and
Latin America
Latin America is the cultural region of the Americas where Romance languages are predominantly spoken, primarily Spanish language, Spanish and Portuguese language, Portuguese. Latin America is defined according to cultural identity, not geogr ...
, it was not until 1765 that the population returned to its pre-1720 level.
Pre-plague city
Sanitation board
At the end of the plague of 1580, the people at Marseille took some measures to attempt to control the future spread of disease. The city council of Marseille established a sanitation board, whose members were to be drawn from the city council as well as the doctors of the city. The exact founding date of the board is unknown, but its existence is first mentioned in a 1622 text of the
Parliament of Aix. The newly established sanitation board made a series of recommendations to maintain the health of the city.
They established a bureaucracy to maintain the health of Marseille. In addition to protecting the city from exterior vulnerabilities, the sanitation board sought to build a public infrastructure. The first public hospital of Marseille was also built during this time period and was given a full-sized staff of doctors and nurses. Additionally, the sanitation board was responsible for the accreditation of local doctors. Citing the vast amount of misinformation that propagates during a plague, the sanitation board sought to, at a minimum, provide citizens with a list of doctors who were believed to be credible.
The sanitation board was one of the first executive bodies formed by the city of Marseille. It was staffed to support the board's increasing responsibilities.
Quarantine system
The Sanitation Board established a three-tiered control and quarantine system. Members of the board inspected all incoming ships and gave them one of three "bills of health". The “bill of health” then determined the level of access to the city by the ship and its cargo.
A delegation of members of the sanitation board was to greet every incoming ship. They reviewed the captain's log, which recorded every city where the ship had landed, and checked it against the sanitation board's master list of cities throughout the Mediterranean that had rumors of recent plague incidents. The delegation also inspected all the cargo, crew and passengers, looking for signs of possible disease. If the team saw signs of disease, the ship was not allowed to land at a Marseille dock.
If the ship passed that first test and there were no signs of disease, but the ship's itinerary included a city with documented plague activity, the ship was sent to the second tier of quarantine, at islands outside of Marseille harbour. The criteria for the ''
lazarets'' were ventilation (to drive off what was thought to be the miasma of disease), be near the sea to facilitate communication and pumping of water to clean, and to be isolated yet easily accessible.
Even a clean bill of health for a ship required a minimum of 18 days' quarantine at the off-island location. During such time, the crew would be held in one of the lazarettos/lazarets that were constructed around the city. The lazarettos were also classified in relation to bills of health given to the ship and individuals. With a clean bill, a crewman went to the largest quarantine site, which was equipped with stores and was large enough to accommodate many ships and crews at a time. If crew members were believed subject to a possibility of plague, they were sent to the more isolated quarantine site, which was built on an island off the coast of the Marseille harbour. The crew and passengers were required to wait there for 50 to 60 days to see if they developed any sign of plague.
Once crews served their time, they were allowed into the city in order to sell their goods and enjoy themselves prior to departure.
Outbreak and fatalities
This great outburst of plague was the last recurrence of a
pandemic of bubonic plague, following the devastating episodes which began in the early fourteenth century; the first known instance of bubonic plague in Marseille was the arrival of the
Black Death
The Black Death was a bubonic plague pandemic that occurred in Europe from 1346 to 1353. It was one of the list of epidemics, most fatal pandemics in human history; as many as people perished, perhaps 50% of Europe's 14th century population. ...
in the autumn of 1347. According to contemporary reports, in May 1720,''
Yersinia pestis
''Yersinia pestis'' (''Y. pestis''; formerly ''Pasteurella pestis'') is a Gram-negative bacteria, gram-negative, non-motile bacteria, non-motile, coccobacillus Bacteria, bacterium without Endospore, spores. It is related to pathogens ''Yer ...
'' arrived at the port of Marseille from the
Levant
The Levant ( ) is the subregion that borders the Eastern Mediterranean, Eastern Mediterranean sea to the west, and forms the core of West Asia and the political term, Middle East, ''Middle East''. In its narrowest sense, which is in use toda ...
upon the merchant ship ''Grand-Saint-Antoine.'' The vessel had departed from
Sidon
Sidon ( ) or better known as Saida ( ; ) is the third-largest city in Lebanon. It is located on the Mediterranean Sea, Mediterranean coast in the South Governorate, Lebanon, South Governorate, of which it is the capital. Tyre, Lebanon, Tyre, t ...
in
Lebanon
Lebanon, officially the Republic of Lebanon, is a country in the Levant region of West Asia. Situated at the crossroads of the Mediterranean Basin and the Arabian Peninsula, it is bordered by Syria to the north and east, Israel to the south ...
, having previously called at
Smyrna
Smyrna ( ; , or ) was an Ancient Greece, Ancient Greek city located at a strategic point on the Aegean Sea, Aegean coast of Anatolia, Turkey. Due to its advantageous port conditions, its ease of defence, and its good inland connections, Smyrna ...
,
Tripoli, and plague-ridden
Cyprus
Cyprus (), officially the Republic of Cyprus, is an island country in the eastern Mediterranean Sea. Situated in West Asia, its cultural identity and geopolitical orientation are overwhelmingly Southeast European. Cyprus is the List of isl ...
. A Turkish passenger was the first to be infected and soon died, followed by several crew members and the ship's surgeon. The ship was refused entry to the port of
Livorno
Livorno () is a port city on the Ligurian Sea on the western coast of the Tuscany region of Italy. It is the capital of the Province of Livorno, having a population of 152,916 residents as of 2025. It is traditionally known in English as Leghorn ...
.
When it arrived at Marseille, it was promptly placed under
quarantine
A quarantine is a restriction on the movement of people, animals, and goods which is intended to prevent the spread of disease or pests. It is often used in connection to disease and illness, preventing the movement of those who may have bee ...
in the ''
lazaret'' by the port authorities. Due largely to Marseille's monopoly on French trade with the Levant, this important port had a large stock of imported goods in warehouses. It was also expanding its trade with other areas of the Middle East and emerging markets in the New World. Powerful city merchants wanted the
silk
Silk is a natural fiber, natural protein fiber, some forms of which can be weaving, woven into textiles. The protein fiber of silk is composed mainly of fibroin and is most commonly produced by certain insect larvae to form cocoon (silk), c ...
and
cotton
Cotton (), first recorded in ancient India, is a soft, fluffy staple fiber that grows in a boll, or protective case, around the seeds of the cotton plants of the genus '' Gossypium'' in the mallow family Malvaceae. The fiber is almost pure ...
cargo of the ship for the great medieval fair at
Beaucaire and pressured authorities to lift the quarantine.
A few days later, the disease broke out in the city. Hospitals were quickly overwhelmed, and residents panicked, driving the sick from their homes and out of the city. Mass graves were dug but were quickly filled. Eventually, the number of dead overcame city public health efforts, until thousands of corpses lay scattered and in piles around the city.
Attempts to stop the spread of plague included an Act of the
Parlement of Aix that levied the death penalty for any communication between Marseille and the rest of Provence. To enforce this separation, a plague wall, or ''mur de la peste'', was erected across the countryside. The wall was built of dry stone, high and thick, with guard posts set back from the wall. Remains of the wall can still be seen in different parts of the Plateau de Vaucluse.
At the onset of the plague,
Nicolas Roze
Nicolas Roze (17 January 1745 – 30 September 1819) was a French composer and music theorist.
Biography
Born in Mercurey, Roze was a choirboy at the , Nicolas Roze was noted for his beautiful voice and received a good musical training. He was ...
, who had been vice-consul at a factory on the
Peloponnese
The Peloponnese ( ), Peloponnesus ( ; , ) or Morea (; ) is a peninsula and geographic region in Southern Greece, and the southernmost region of the Balkans. It is connected to the central part of the country by the Isthmus of Corinth land bridg ...
coast and dealt against epidemics there, proposed his services to the local authorities, the échevins. On the strength of his experience dealing with the Greek outbreaks, he was made General Commissioner for the Rive-Neuve neighbourhood. He established a quarantine by setting up
checkpoints, and went as far as building gallows as a deterrence against looters. He also had five large
mass grave
A mass grave is a grave containing multiple human corpses, which may or may Unidentified decedent, not be identified prior to burial. The United Nations has defined a criminal mass grave as a burial site containing three or more victims of exec ...
s dug out, converted La Corderie into a field hospital, and organised distribution of humanitarian supply to the population. He furthermore organised supply for the city itself.
On 16 September 1720, Roze personally headed a 150-strong group of volunteers and prisoners to remove 1,200 corpses in the poor neighbourhood of the Esplanade de la Tourette. Some of the corpses were three weeks old and contemporary sources describe them as "hardly human in shape and set in movement by maggots". In half an hour, the corpses were thrown into open pits that were then filled with lime and covered with soil.
[
Out of 1,200 volunteers and prisoners deployed to fight the plague, only three survived. Roze himself caught the disease, but survived, although chances of survival without modern medicine are between 20 and 40%.][
During a two-year period, 50,000 of Marseille's total population of 90,000 died. An additional 50,000 people in other areas succumbed as the plague spread north, eventually reaching ]Aix-en-Provence
Aix-en-Provence, or simply Aix, is a List of communes in France with over 20,000 inhabitants, city and Communes of France, commune in southern France, about north of Marseille. A former capital of Provence, it is the Subprefectures in France, s ...
, Arles
Arles ( , , ; ; Classical ) is a coastal city and Communes of France, commune in the South of France, a Subprefectures in France, subprefecture in the Bouches-du-Rhône Departments of France, department of the Provence-Alpes-Côte d'Azur Reg ...
, Apt and Toulon
Toulon (, , ; , , ) is a city in the Provence-Alpes-Côte d'Azur region of southeastern France. Located on the French Riviera and the historical Provence, it is the prefecture of the Var (department), Var department.
The Commune of Toulon h ...
. Estimates indicate an overall death rate of between 25 and 50% for the population in the larger area, with the city of Marseille at 40%, the area of Toulon at above 50%, and the area of Aix and Arles at 25%.
After the plague subsided, the royal government strengthened the plague defenses of the port, building the waterside ''Lazaret d'Arenc''. A double line of fifteen-foot walls ringed the whitewashed compound, pierced on the waterside to permit the offloading of cargo from lighters. Merchantmen were required to pass inspection at an island further out in the harbour, where crews and cargoes were examined.
Recent research
In 1998, an excavation of a mass grave of victims of the bubonic plague outbreak was conducted by scholars from the Université de la Méditerranée.[Signoli, Seguy, Biraben, Dutour & Belle (2002).] The excavation provided an opportunity to study more than 200 skeletons from an area in the second arrondissement
An arrondissement (, , ) is any of various administrative divisions of France, Belgium, Haiti, and certain other Francophone countries, as well as the Netherlands.
Europe
France
The 101 French departments are divided into 342 ''arrondissem ...
in Marseille, known as the Monastery of the Observance. In addition to modern laboratory testing, archival records were studied to determine the conditions and dates surrounding the use of this mass grave. This multidisciplinary approach revealed previously unknown facts and insights concerning the epidemic of 1722. The reconstruction of the skull of one body, a 15-year-old boy, revealed the first historical evidence of an autopsy
An autopsy (also referred to as post-mortem examination, obduction, necropsy, or autopsia cadaverum) is a surgical procedure that consists of a thorough examination of a corpse by dissection to determine the cause, mode, and manner of deat ...
dated to the spring of 1722. The anatomic techniques used appear to be identical to those described in a surgical book dating from 1708.
See also
* List of Bubonic plague outbreaks
* Plague of Justinian
The plague of Justinian or Justinianic plague (AD 541–549) was an epidemic of Plague (disease), plague that afflicted the entire Mediterranean basin, Mediterranean Basin, Europe, and the Near East, especially the Sasanian Empire and the Byza ...
* Popular revolt in late medieval Europe
Popular revolts in late medieval Europe were uprisings and rebellions by peasants in the countryside, or the Burgess (title), burgesses in towns, against nobleman, nobles, abbots and kings during the upheavals between 1300 and 1500, part of a larg ...
* Moscow plague riot of 1771
* Second plague pandemic
The second plague pandemic was a major series of epidemics of Plague (disease), plague that started with the Black Death, which reached medieval Europe in 1346 and killed up to half of the population of Eurasia in the next four years. It followed ...
* Third plague pandemic
* Nicolas Roze (chevalier)
Nicolas Roze, better known as Chevalier Roze (Marseille, 1675-1733) was a French aristocrat. He is remembered for his heroism in 1720 during the Great Plague of Marseille.
Biography
Nicolas Roze was born to a family of land owners from Solli� ...
* COVID-19 in France
Notes
References
*
* , Chapter 42, pages 360–378.
*
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External links
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*
1720 disasters
1720 in health
18th-century disease outbreaks
1720 in France
History of Europe
Disease outbreaks in France
History of Marseille
Second plague pandemic
18th-century epidemics
18th-century disasters in Europe
{{Epidemics