Graham Charles Walker (born 1948)Book of Members: Chapter W
/ref> is an American biologist, notable for his work explicating the structure and function of proteins involved in

DNA repair DNA repair is a collection of processes by which a cell (biology), cell identifies and corrects damage to the DNA molecules that encode its genome. A weakened capacity for DNA repair is a risk factor for the development of cancer. DNA is cons ...

and

mutagenesis Mutagenesis () is a process by which the genetic information of an organism is changed by the production of a mutation. It may occur spontaneously in nature, or as a result of exposure to mutagens. It can also be achieved experimentally using lab ...

, with applications for cancer, and for understanding

rhizobium ''Rhizobium'' is a genus of Gram-negative soil bacteria that fix nitrogen. ''Rhizobium'' species form an endosymbiotic nitrogen-fixing association with roots of (primarily) legumes and other flowering plants. The bacteria colonize plant ce ...

(bacterial) functions that infect plants and mammals. In addition to his scientific achievements, Walker is coordinating a program at

MIT The Massachusetts Institute of Technology (MIT) is a private research university in Cambridge, Massachusetts, United States. Established in 1861, MIT has played a significant role in the development of many areas of modern technology and sc ...

to develop curricular materials in biology.

Biography

Walker earned a B.Sc. degree from

Carleton University Carleton University is an English-language public university, public research university in Ottawa, Ontario, Canada. Founded in 1942 as Carleton College, the institution originally operated as a private, non-denominational evening college to se ...

, and his Ph.D. in 1974 from the

University of Illinois The University of Illinois Urbana-Champaign (UIUC, U of I, Illinois, or University of Illinois) is a public university, public land-grant university, land-grant research university in the Champaign–Urbana metropolitan area, Illinois, United ...

. He did postdoctoral work at the

and at

University of California, Berkeley The University of California, Berkeley (UC Berkeley, Berkeley, Cal, or California), is a Public university, public Land-grant university, land-grant research university in Berkeley, California, United States. Founded in 1868 and named after t ...

with Bruce Ames. He is currently a professor at

Notable publications

* Errol C. Friedberg, Graham C. Walker, Wolfram Siede, and Richard D. Wood, ''DNA Repair and Mutagenesis'' (2005 edition of notable textbook) * Bradley T. Smith, Alan D. Grossman, and Graham C. Walker, "Visualization of Mismatch Repair in Bacterial Cells", ''Molecular Cell'', v.8, pp. 1197–1206 (Dec. 2001) * LeVier, K., Phillips, R.W., Grippe, V.K., Roop II, R.M. and Walker, G.C. Similar requirements of a plant symbiont and a mammalian pathogen for prolonged intracellular survival. Science 287:2492-2493 (2000) * G. C. Walker, "Mutagenesis and inducible responses to deoxyribonucleic acid damage in ''Escheriscia coli''", ''Microbiological Reviews'' (full text available a
PubMed Central

Awards

* 1970 - Woodrow Wilson National Fellow * 1978-1982 - Rita Allen Foundation Scholar * 1994 - Elected Fellow,

American Academy of Microbiology American(s) may refer to: * American, something of, from, or related to the United States of America, commonly known as the "United States" or "America" ** Americans, citizens and nationals of the United States of America ** American ancestry, p ...

* 2004 - Elected Fellow,

American Academy of Arts and Sciences The American Academy of Arts and Sciences (The Academy) is one of the oldest learned societies in the United States. It was founded in 1780 during the American Revolution by John Adams, John Hancock, James Bowdoin, Andrew Oliver, and other ...

. * 2006 - Environmental Mutagen Society Award * 2009 - Elected Fellow,

American Association for the Advancement of Science The American Association for the Advancement of Science (AAAS) is a United States–based international nonprofit with the stated mission of promoting cooperation among scientists, defending scientific freedom, encouraging scientific responsib ...

. * 2013 - Elected Member,

National Academy of Sciences The National Academy of Sciences (NAS) is a United States nonprofit, NGO, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the ...

. *

American Cancer Society The American Cancer Society (ACS) is a nationwide non-profit organization dedicated to eliminating cancer. The ACS publishes the journals ''Cancer'', '' CA: A Cancer Journal for Clinicians'' and '' Cancer Cytopathology''. History The society w ...

Research Professor * Charles Ross Scholar Award for Cancer Research * Arthur C. Smith Award * Stone Lectureship, Pennsylvania State University

References

MIT faculty profile

Footnotes

Howard Hughes Medical Investigators Living people 1948 births Carleton University alumni University of California, Berkeley people Massachusetts Institute of Technology School of Science faculty University of Illinois alumni Members of the United States National Academy of Sciences Fellows of the American Academy of Arts and Sciences Fellows of the American Association for the Advancement of Science 21st-century American biologists {{US-biologist-stub