Gluma is a

brand-name A brand is a name, term, design, symbol or any other feature that distinguishes one seller's goods or service from those of other sellers. Brands are used in business, marketing, and advertising for recognition and, importantly, to create and ...

desensitizer, used in

dentistry Dentistry, also known as dental medicine and oral medicine, is the branch of medicine focused on the Human tooth, teeth, gums, and Human mouth, mouth. It consists of the study, diagnosis, prevention, management, and treatment of diseases, dis ...

to treat sensitivity, product created by manufacturer Heraeus Kulzer, a German company.

Use

Its formula of 5%

glutaraldehyde Glutaraldehyde is an organic compound with the formula . The molecule consists of a five carbon chain doubly terminated with formyl (CHO) groups. It is usually used as a solution in water, and such solutions exists as a collection of hydrates, ...

and 35% HEMA (hydroxy-

ethyl methacrylate Ethyl methacrylate is the organic compound with the formula C2H5O2CC(CH3)=CH2. A colorless liquid, it is a common monomer for the preparation of acrylate polymer An acrylate polymer (also known as acrylic or polyacrylate) is any of a group of ...

) in

water Water is an inorganic compound with the chemical formula . It is a transparent, tasteless, odorless, and Color of water, nearly colorless chemical substance. It is the main constituent of Earth's hydrosphere and the fluids of all known liv ...

is used to help control both hypersensitive

dentin Dentin ( ) (American English) or dentine ( or ) (British English) () is a calcified tissue (biology), tissue of the body and, along with tooth enamel, enamel, cementum, and pulp (tooth), pulp, is one of the four major components of teeth. It i ...

and reduce the incidence of post-operative sensitivity in restorative

procedures. It’s also useful as a cavity

disinfectant A disinfectant is a chemical substance or compound used to inactivate or destroy microorganisms on inert surfaces. Disinfection does not necessarily kill all microorganisms, especially resistant bacterial spores; it is less effective than ...

, a rewetting agent and an

adhesion Adhesion is the tendency of dissimilar particles or interface (matter), surfaces to cling to one another. (Cohesion (chemistry), Cohesion refers to the tendency of similar or identical particles and surfaces to cling to one another.) The ...

promoter (when combined with most dentin bonding systems). Research indicates that when used as a desensitizer under bonded restorative material, Gluma has no significant influence on bond strength, unlike some other liners, which contribute to a decrease in bond strength. In one study,

potassium nitrate Potassium nitrate is a chemical compound with a sharp, salty, bitter taste and the chemical formula . It is a potassium salt of nitric acid. This salt consists of potassium cations and nitrate anions , and is therefore an alkali metal nit ...

was more effective at reducing sensitivity.

Method of action

The glutaraldehyde in Gluma works by occluding (blocking) the microscopic tubules that compose

, thereby preventing the flow of fluid and decreasing sensitivity. Gluteraldehyde induces coagulation of proteins in dentinal tubules, which reacts with the serum albumin in the dentinal fluid to cause its precipitation. HEMA forms deep resinous tags and then occludes the dentinal tubules.Sanjay Miglani, Vivek Aggarwal, and Bhoomika Ahuja
Dentin hypersensitivity: Recent trends in management
''J Conserv Dent'' 2010 Oct-Dec;13(4): 218–224

References

External links

Heraeus Kulzer

Disinfectants