Giuffre or Giuffrè is a surname. Notable people with the surname include:
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Aldo Giuffrè (1924–2010), Italian film actor and comedian who appeared in over 90 films
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Antonino Giuffrè (born 1945), Italian former mafioso from Caccamo, Palermo, Sicily
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Carlo Giuffrè (1928–2018), Italian film actor
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Gaetano Giuffrè (1918–2018), Italian-Greek composer
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Jimmy Giuffre (1921–2008), American jazz composer, arranger, saxophone and clarinet player
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Matthew Giuffre (born 1982), Canadian squash player
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Virginia Giuffre (1983–2025), an American-Australian woman who accused Jeffrey Epstein and his associates of rape
See also
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