Gilda H. Loew
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Gilda H. Loew (1930–January 5, 2001) was an American chemist known for applying
computational chemistry Computational chemistry is a branch of chemistry that uses computer simulations to assist in solving chemical problems. It uses methods of theoretical chemistry incorporated into computer programs to calculate the structures and properties of mol ...
to biology. She was elected a Fellow of the
American Physical Society The American Physical Society (APS) is a not-for-profit membership organization of professionals in physics and related disciplines, comprising nearly fifty divisions, sections, and other units. Its mission is the advancement and diffusion of ...
in 1975.


Career

A native of
Brooklyn, New York Brooklyn is a Boroughs of New York City, borough of New York City located at the westernmost end of Long Island in the New York (state), State of New York. Formerly an independent city, the borough is coextensive with Kings County, one of twelv ...
, Loew attended
Erasmus Hall High School Erasmus Hall High School was a four-year public high school located at 899–925 Flatbush Avenue between Church and Snyder Avenues in the Flatbush, Brooklyn, Flatbush neighborhood of the New York City borough (New York City), borough of Brookly ...
and then went on to earn a bachelor's degree from
New York University New York University (NYU) is a private university, private research university in New York City, New York, United States. Chartered in 1831 by the New York State Legislature, NYU was founded in 1832 by Albert Gallatin as a Nondenominational ...
and a master's from Columbia, both in chemistry, before going on to doctoral work at
UC Berkeley The University of California, Berkeley (UC Berkeley, Berkeley, Cal, or California), is a public land-grant research university in Berkeley, California, United States. Founded in 1868 and named after the Anglo-Irish philosopher George Berkele ...
, where she earned a PhD in
chemical physics Chemical physics is a branch of physics that studies chemical processes from a physical point of view. It focuses on understanding the physical properties and behavior of chemical systems, using principles from both physics and chemistry. This ...
. In the 1950s and 1960s, she held a number of research positions, at the
Lawrence Radiation Laboratory Lawrence may refer to: Education Colleges and universities * Lawrence Technological University, a university in Southfield, Michigan, United States * Lawrence University, a liberal arts university in Appleton, Wisconsin, United States Preparator ...
, the
Lockheed Missiles and Space Company Lockheed Missiles and Space Company (LMSC) was a unit of the Lockheed Corporation "Missiles, Space, and Electronics Systems Group." LMSC was started by Willis Hawkins who served as its president. After Lockheed merged with Martin-Marietta the ...
and the Hansen Laboratories,
Stanford University Leland Stanford Junior University, commonly referred to as Stanford University, is a Private university, private research university in Stanford, California, United States. It was founded in 1885 by railroad magnate Leland Stanford (the eighth ...
. According to
Harel Weinstein Harel is both a surname and a given name. Notable people with the name include: Surname * Alon Harel (1957–), Israeli law professor * Dan Harel (1955–), general in the Israeli Defense Force * David Harel (1950–), computer sciences professor ...
and Hugo O. Villar, she became "a pioneer in the application of
computational chemistry Computational chemistry is a branch of chemistry that uses computer simulations to assist in solving chemical problems. It uses methods of theoretical chemistry incorporated into computer programs to calculate the structures and properties of mol ...
to problems in the biological sciences". After several years as an associate professor of physics at
Pomona College Pomona College ( ) is a private university, private Liberal arts colleges in the United States, liberal arts college in Claremont, California. It was established in 1887 by a group of Congregationalism in the United States, Congregationalists ...
, Loew was appointed as an adjunct professor in the department of genetics at Stanford in 1969, holding this position until 1979, when she established the Molecular Research Institute in
Palo Alto Palo Alto ( ; Spanish language, Spanish for ) is a charter city in northwestern Santa Clara County, California, United States, in the San Francisco Bay Area, named after a Sequoia sempervirens, coastal redwood tree known as El Palo Alto. Th ...
, which she led for two decades. She was also an adjunct professor at
Rockefeller University The Rockefeller University is a Private university, private Medical research, biomedical Research university, research and graduate-only university in New York City, New York. It focuses primarily on the biological and medical sciences and pro ...
between 1978 and 1990. The research of Loew's that remained critical to those that followed her was the
cytochrome P450 Cytochromes P450 (P450s or CYPs) are a Protein superfamily, superfamily of enzymes containing heme as a cofactor (biochemistry), cofactor that mostly, but not exclusively, function as monooxygenases. However, they are not omnipresent; for examp ...
protein family and her thirty years of investigation into their characteristics and properties, along with their three dimensional structure and how they interfaced with enzymatic substrates. In doing this research, Loew pioneered using new forms of technology that became available over the years, including numerous advances in computer modeling of proteins. Loew, related to said research, wrote a chapter on the properties of iron porphyrins for the first volume of the textbook series ''Physical Bioinorganic Chemistry'' in 1983.


Legacy

The International Society of Quantum Biology and Pharmacology (ISQBP) established the ISQBP Loew Lectureship in her memory in 2004, along with the Gilda Loew Memorial Award after donations were set up by her husband. The following year, the Gilda Loew Memorial Meeting was organized where over 20 speakers presented on topics that were of interest to Loew and her past research.


Personal life

Loew was married to Gregory Loew and had five children and three grandchildren at the time of her death from breast cancer at 70 years old on January 5, 2001.


References


Further reading

* {{DEFAULTSORT:Loew, Gilda H. American women chemists University of California, Berkeley alumni Stanford University faculty 1930 births 2001 deaths 20th-century American women scientists 20th-century American chemists Columbia Graduate School of Arts and Sciences alumni Columbia University alumni Scientists from Brooklyn American physical chemists Women physical chemists Fellows of the American Physical Society Pomona College faculty Rockefeller University faculty Deaths from breast cancer in California