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Gerhard Henrik Armauer Hansen (; 29 July 1841 – 12 February 1912) was a Norwegian physician, remembered for his identification of the
bacterium Bacteria (; : bacterium) are ubiquitous, mostly free-living organisms often consisting of one biological cell. They constitute a large domain of prokaryotic microorganisms. Typically a few micrometres in length, bacteria were among the ...
''
Mycobacterium leprae ''Mycobacterium leprae'' (also known as the leprosy bacillus or Hansen's bacillus) is one of the two species of bacteria that cause Hansen's disease (leprosy), a chronic but curable infectious disease that damages the peripheral nerves and ta ...
'' in 1873 as the causative agent of
leprosy Leprosy, also known as Hansen's disease (HD), is a Chronic condition, long-term infection by the bacteria ''Mycobacterium leprae'' or ''Mycobacterium lepromatosis''. Infection can lead to damage of the Peripheral nervous system, nerves, respir ...
. His distinguished work was recognized at the International Leprosy Congress held at Bergen in 1909.


Life

Hansen was born in
Bergen Bergen (, ) is a city and municipalities of Norway, municipality in Vestland county on the Western Norway, west coast of Norway. Bergen is the list of towns and cities in Norway, second-largest city in Norway after the capital Oslo. By May 20 ...
, Norway, and attended the Bergen Cathedral School. He worked at Rikshospitalet in Christiania (now Oslo) and as a doctor in
Lofoten Lofoten ( , ; ; ) is an archipelago and a Districts of Norway, traditional district in the county of Nordland, Norway. Lofoten has distinctive scenery with dramatic mountains and peaks, open sea and sheltered bays, beaches, and untouched lands. T ...
. In 1868 Hansen returned to Bergen to study leprosy while working at Lungegård Hospital () with Daniel Cornelius Danielssen, a noted expert. Leprosy was regarded as largely
hereditary Heredity, also called inheritance or biological inheritance, is the passing on of traits from parents to their offspring; either through asexual reproduction or sexual reproduction, the offspring cells or organisms acquire the genetic inform ...
or otherwise miasmic in origin. Hansen concluded on the basis of
epidemiological Epidemiology is the study and analysis of the distribution (who, when, and where), patterns and Risk factor (epidemiology), determinants of health and disease conditions in a defined population, and application of this knowledge to prevent dise ...
studies that leprosy was a specific
disease A disease is a particular abnormal condition that adversely affects the structure or function (biology), function of all or part of an organism and is not immediately due to any external injury. Diseases are often known to be medical condi ...
with a specific cause. In 1870–71 Hansen travelled to
Bonn Bonn () is a federal city in the German state of North Rhine-Westphalia, located on the banks of the Rhine. With a population exceeding 300,000, it lies about south-southeast of Cologne, in the southernmost part of the Rhine-Ruhr region. This ...
and
Vienna Vienna ( ; ; ) is the capital city, capital, List of largest cities in Austria, most populous city, and one of Federal states of Austria, nine federal states of Austria. It is Austria's primate city, with just over two million inhabitants. ...
to gain the training necessary for him to prove his
hypothesis A hypothesis (: hypotheses) is a proposed explanation for a phenomenon. A scientific hypothesis must be based on observations and make a testable and reproducible prediction about reality, in a process beginning with an educated guess o ...
. In 1873, he announced the discovery of ''Mycobacterium leprae'' in the tissues of all people with the condition, although he did not identify them as bacteria, and received little support. The discovery was made with a "new and better" microscope. In 1879 Hansen gave tissue samples to Albert Neisser, who then successfully stained the bacteria and announced his findings in 1880, claiming to have discovered the disease-causing organism. There was some dispute between Neisser and Hansen, Hansen as discoverer of the bacillus and Neisser as identifier of it as the
etiological Etiology (; alternatively spelled aetiology or ætiology) is the study of causation or origination. The word is derived from the Greek word ''()'', meaning "giving a reason for" (). More completely, etiology is the study of the causes, origin ...
agent. Neisser tried to downplay the assistance of Hansen. Hansen's claim was weakened by his failure to produce a pure
microbiological culture A microbiological culture, or microbial culture, is a method of multiplying microorganism, microbial organisms by letting them reproduce in predetermined culture medium under controlled laboratory conditions. Microbial cultures are foundational a ...
in an artificial medium, or to prove that the
rod-shaped Bacterial cellular morphologies are the shapes that are characteristic of various types of bacteria and often key to their identification. Their direct examination under a light microscope enables the classification of these bacteria (and archae ...
organisms were infectious. Further, Hansen had attempted to infect at least one female patient with the nodular form of leprosy without consent, and although no damage was caused, the case ended up in court and Hansen lost his post at the hospital. The case helped introduce
informed consent Informed consent is an applied ethics principle that a person must have sufficient information and understanding before making decisions about accepting risk. Pertinent information may include risks and benefits of treatments, alternative treatme ...
for
medical research Medical research (or biomedical research), also known as health research, refers to the process of using scientific methods with the aim to produce knowledge about human diseases, the prevention and treatment of illness, and the promotion of ...
in Norway. Hansen remained medical officer for leprosy in Norway and it was through his efforts that the leprosy acts of 1877 and 1885 were passed, leading to a steady decline of the disease in Norway from 1,800 known cases in 1875 to just 575 cases in 1901. Hansen had had
syphilis Syphilis () is a sexually transmitted infection caused by the bacterium ''Treponema pallidum'' subspecies ''pallidum''. The signs and symptoms depend on the stage it presents: primary, secondary, latent syphilis, latent or tertiary. The prim ...
since the 1860s but died of
heart disease Cardiovascular disease (CVD) is any disease involving the heart or blood vessels. CVDs constitute a class of diseases that includes: coronary artery diseases (e.g. angina pectoris, angina, myocardial infarction, heart attack), heart failure, ...
. He was an atheist.


Women's rights

He was a co-founder and a board member of the Bergen chapter of the
Norwegian Association for Women's Rights The Norwegian Association for Women's Rights (; NKF) is Norway's oldest and preeminent women's rights, women's and girls' rights organization that works "to promote gender equality and all women's and girls' human rights through political reform, ...
, led by his sister, prominent women's rights advocate .


Honors

* Leprosy Museum () at St. Jørgen Hospital in Bergen has been dedicated to Hansen. * Haukeland University Hospital has established as a research facility operated by the
University of Bergen The University of Bergen () is a public university, public research university in Bergen, Norway. As of 2021, the university had over 4,000 employees and 19,000 students. It was established by an act of parliament in 1946 consolidating several sci ...
. * In Jerusalem, a 19th-century leprosarium has borne Hansen's name since 1950. It has been reconstructed into an art center while preserving the physician's surname in its title. *Armauer Hansen Research Institute (AHRI) in Addis Ababa, Ethiopia under the ministry of Health is named after Hansen. AHRI is a biomedical research institute working in tuberculosis, HIV, malaria, leishmaniasis training, and research.


References


External links

* {{DEFAULTSORT:Hansen, Gerhard Armauer 1841 births 1912 deaths Physicians from Bergen People educated at the Bergen Cathedral School University of Oslo alumni Norwegian atheists Norwegian medical researchers Norwegian physicians Leprologists Norwegian public health doctors Recipients of the St. Olav's Medal Norwegian Association for Women's Rights people