Gerald M. "Jerry" Reaven (July 28, 1928 – February 12, 2018) was an

American American(s) may refer to: * American, something of, from, or related to the United States of America, commonly known as the "United States" or "America" ** Americans, citizens and nationals of the United States of America ** American ancestry, p ...

endocrinologist Endocrinology (from ''endocrine'' + '' -ology'') is a branch of biology and medicine dealing with the endocrine system, its diseases, and its specific secretions known as hormones. It is also concerned with the integration of developmental events ...

and professor emeritus in medicine at the

Stanford University School of Medicine The Stanford University School of Medicine is the medical school of Stanford University and is located in Stanford, California, United States. It traces its roots to the Medical Department of the University of the Pacific, founded in San Fra ...

Stanford, California Stanford is a census-designated place (CDP) in the northwest corner of Santa Clara County, California, United States. It is the home of Stanford University, after which it was named. The CDP's population was 21,150 at the United States Census, ...

, United States. Reaven's work on

insulin resistance Insulin resistance (IR) is a pathological response in which cells in insulin-sensitive tissues in the body fail to respond normally to the hormone insulin or downregulate insulin receptors in response to hyperinsulinemia. Insulin is a horm ...

and

diabetes mellitus Diabetes mellitus, commonly known as diabetes, is a group of common endocrine diseases characterized by sustained hyperglycemia, high blood sugar levels. Diabetes is due to either the pancreas not producing enough of the hormone insulin, or th ...

with John W. Farquhar goes back at least to 1965. A long-term researcher into

diabetes Diabetes mellitus, commonly known as diabetes, is a group of common endocrine diseases characterized by sustained high blood sugar levels. Diabetes is due to either the pancreas not producing enough of the hormone insulin, or the cells of th ...

, he achieved significant notability with his 1988 Banting Lecture (organized annually by the

American Diabetes Association The American Diabetes Association (ADA) is a United States-based nonprofit that seeks to educate the public about diabetes and to help those affected by it through funding research to manage, cure and prevent diabetes, including type 1 diabetes ...

in memory of

Frederick Banting Sir Frederick Grant Banting (November 14, 1891 – February 21, 1941) was a Canadian pharmacologist, orthopedist, and field surgeon. For his co-discovery of insulin and its therapeutic potential, Banting was awarded the Nobel Prize in Physi ...

). In his lecture, he propounded the theory that

central obesity Abdominal obesity, also known as central obesity and truncal obesity, is the human condition of an excessive concentration of visceral fat around the stomach and abdomen to such an extent that it is likely to harm its bearer's health. Abdominal ...

(male-type or apple-shaped obesity), diabetes and

hypertension Hypertension, also known as high blood pressure, is a Chronic condition, long-term Disease, medical condition in which the blood pressure in the artery, arteries is persistently elevated. High blood pressure usually does not cause symptoms i ...

(high blood pressure) have a common cause in

and

impaired glucose tolerance Prediabetes is a component of metabolic syndrome and is characterized by elevated blood sugar levels that fall below the threshold to diagnose diabetes mellitus. It usually does not cause symptoms, but people with prediabetes often have obesity ( ...

. Initially titled "syndrome X", the constellation of symptoms is now known as the

metabolic syndrome Metabolic syndrome is a clustering of at least three of the following five medical conditions: abdominal obesity, high blood pressure, high blood sugar, high serum triglycerides, and low serum high-density lipoprotein (HDL). Metabolic syndro ...

and an object of extensive scientific inquiry, especially given that the combination strongly predisposes for

cardiovascular disease Cardiovascular disease (CVD) is any disease involving the heart or blood vessels. CVDs constitute a class of diseases that includes: coronary artery diseases (e.g. angina, heart attack), heart failure, hypertensive heart disease, rheumati ...

. Still, Reaven believes that contemporary criteria are arbitrary and that it may not be necessary to define it as a diagnostic entity more than a pathophysiological parameter. He obtained his academic qualifications at the

University of Chicago The University of Chicago (UChicago, Chicago, or UChi) is a Private university, private research university in Chicago, Illinois, United States. Its main campus is in the Hyde Park, Chicago, Hyde Park neighborhood on Chicago's South Side, Chic ...

and did his internship there. After research work in Stanford and two years in the U.S.

Army medical corps A medical corps is generally a military branch or officer corps responsible for medical care for serving military personnel. Such officers are typically military physicians. List of medical corps The following organizations are examples of med ...

he completed his residency at the

University of Michigan The University of Michigan (U-M, U of M, or Michigan) is a public university, public research university in Ann Arbor, Michigan, United States. Founded in 1817, it is the oldest institution of higher education in the state. The University of Mi ...

. He then took up a

US Public Health Service The United States Public Health Service (USPHS or PHS) is a collection of agencies of the Department of Health and Human Services which manages public health, containing nine out of the department's twelve operating divisions. The assistant se ...

research post at Stanford, where he progressed to a full professorship in 1970. He led endocrinology and

gerontology Gerontology ( ) is the study of the social, culture, cultural, psychology, psychological, cognitive, and biology, biological aspects of aging. The word was coined by Ilya Ilyich Mechnikov in 1903, from the Ancient Greek, Greek ('), meaning "o ...

research.Gerald M. Reaven
curriculum vitae
/ref> Apart from his work at Stanford he was also Senior Vice President for Research for Shaman Pharmaceuticals, Inc. in South San Francisco. He was a member of several research organizations and received numerous prizes for his research achievements. He was co-author of a popular book on Syndrome X and its repercussions on cardiovascular disease.

Footnotes

External links

Interview
- Canadian Association of Cardiac Rehabilitation {{DEFAULTSORT:Reaven, Gerald 1928 births 2018 deaths American endocrinologists Stanford University School of Medicine faculty Pritzker School of Medicine alumni University of Michigan alumni People from Gary, Indiana