George Perry (born April 12, 1953) is a professor of biology and chemistry at the

University of Texas at San Antonio The University of Texas at San Antonio (UTSA or UT San Antonio) is a Public university, public research university in San Antonio, Texas, United States. Established in 1969,dean Dean may refer to: People * Dean (given name) * Dean (surname), a surname of Anglo-Saxon English origin * Dean (South Korean singer), a stage name for singer Kwon Hyuk * Dean Delannoit, a Belgian singer most known by the mononym Dean * Dean Sw ...

of the College of Sciences. Perry is recognized in the field of

Alzheimer's disease Alzheimer's disease (AD) is a neurodegenerative disease and the cause of 60–70% of cases of dementia. The most common early symptom is difficulty in remembering recent events. As the disease advances, symptoms can include problems wit ...

research, particularly for his work on

oxidative stress Oxidative stress reflects an imbalance between the systemic manifestation of reactive oxygen species and a biological system's ability to readily detoxify the reactive intermediates or to repair the resulting damage. Disturbances in the normal ...

Education

Perry received his Bachelor of Arts degree in zoology from

University of California, Santa Barbara The University of California, Santa Barbara (UC Santa Barbara or UCSB) is a Public university, public Land-grant university, land-grant research university in Santa Barbara County, California, United States. Tracing its roots back to 1891 as an ...

. After graduation, he studied at

Scripps Institution of Oceanography Scripps Institution of Oceanography (SIO) is the center for oceanography and Earth science at the University of California, San Diego. Its main campus is located in La Jolla, with additional facilities in Point Loma. Founded in 1903 and incorpo ...

Hopkins Marine Station Hopkins Marine Station is the marine laboratory of Stanford University. It is located south of the university's main campus, in Pacific Grove, California (United States) on the Monterey Peninsula, adjacent to the Monterey Bay Aquarium. It is h ...

Stanford University Leland Stanford Junior University, commonly referred to as Stanford University, is a Private university, private research university in Stanford, California, United States. It was founded in 1885 by railroad magnate Leland Stanford (the eighth ...

, and the

Marine Biological Laboratory The Marine Biological Laboratory (MBL) is an international center for research and education in biological and environmental science. Founded in Woods Hole, Massachusetts, in 1888, the MBL is a private, nonprofit institution that was independent ...

at Woods Hole; he obtained his Ph.D. from the University of California at San Diego in

Marine Biology Marine biology is the scientific study of the biology of marine life, organisms that inhabit the sea. Given that in biology many scientific classification, phyla, family (biology), families and genera have some species that live in the sea and ...

under David Epel in 1979. He then received a postdoctoral fellowship in the Department of Cell Biology in the laboratories of William R. Brinkley, Joseph Bryan and Anthony R. Means at

Baylor College of Medicine The Baylor College of Medicine (BCM) is a private medical school in Houston, Texas, United States. Originally as the Baylor University College of Medicine from 1903 to 1969, the college became independent with the current name and has been se ...

where he laid the foundation for his observations of cytoskeletal abnormalities.

Professional appointments

In 1982, Perry joined the faculty of

Case Western Reserve University Case Western Reserve University (CWRU) is a Private university, private research university in Cleveland, Ohio, United States. It was established in 1967 by a merger between Western Reserve University and the Case Institute of Technology. Case ...

, where he holds an adjunct appointment. He is dean of the College of Sciences and professor of biology at the University of Texas at San Antonio. He is distinguished as one of the top Alzheimer's disease researchers with over 1000 publications, one of the top 100 most-cited scientists in Neuroscience & Behavior and one of the top 25 scientists in free radical research. Perry is highly cited (over 82,500 times;H=138;ISI/over 129,000 times;H=177;Google Scholar) and is recognized as an ISI highly cited researcher. Perry is the current and founding

editor-in-chief An editor-in-chief (EIC), also known as lead editor or chief editor, is a publication's editorial leader who has final responsibility for its operations and policies. The editor-in-chief heads all departments of the organization and is held accoun ...

for the ''

Journal of Alzheimer's Disease The ''Journal of Alzheimer's Disease'' is a peer-reviewed medical journal published by IOS Press covering the etiology, pathogenesis, epidemiology, genetics, treatment, and psychology of Alzheimer's disease. The journal publishes research reports, ...

'', an international multidisciplinary journal that specialises in

. He is also a member of the Alzheimer's Foundation of America Medical, Scientific, and Memory Screening Advisory Board. Perry is fellow of the

American Association for the Advancement of Science The American Association for the Advancement of Science (AAAS) is a United States–based international nonprofit with the stated mission of promoting cooperation among scientists, defending scientific freedom, encouraging scientific responsib ...

Sigma Xi Sigma Xi, The Scientific Research Honor Society () is an international non-profit honor society for scientists and engineers. Sigma Xi was founded at Cornell University by a faculty member and graduate students in 1886 and is one of the oldest ...

Microscopy Society of America The Microscopy Society of America (MSA), founded in 1942 as The Electron Microscope Society of America, is a non-profit organization that provides microanalytical facilities for studies within the sciences. Currently, there are approximately 3000 me ...

, International Engineering and Technology Institute (IETI), Texas Academy of Sciences, past president and past-interim executive director of the Southwestern and Rocky Mountain Division of American Association for the Advancement of Science, past chair of the board of the National Organization of Portuguese Americans and past president of the American Association of Neuropathologists.

Research focus

Perry's research is primarily focused on the mechanism of formation and physiological consequences of the cytopathology of

Alzheimer disease Alzheimer's disease (AD) is a neurodegenerative disease and the cause of 60–70% of cases of dementia. The most common early symptom is difficulty in remembering recent events. As the disease advances, symptoms can include problems with ...

. He has played a key role in elucidating oxidative damage as the initial cytopathological abnormality in

. He is currently working to determine the sequence of events leading to neuronal oxidative damage and the source of the increased

oxygen radicals In chemistry, a radical, also known as a free radical, is an atom, molecule, or ion that has at least one unpaired valence electron. With some exceptions, these unpaired electrons make radicals highly chemically reactive. Many radicals sponta ...

. His current studies focus on two issues: (i) the metabolic basis for the mitochondrial damage restricted to vulnerable

neurons A neuron (American English), neurone (British English), or nerve cell, is an membrane potential#Cell excitability, excitable cell (biology), cell that fires electric signals called action potentials across a neural network (biology), neural net ...

; and (ii) the consequences of RNA oxidation on protein synthesis rate and fidelity.

References

External links

Future Neurology Interview

Journal of Alzheimer's Disease

*
Science Watch Top 20 Alzheimer's Researchers

PBS Interview

Express-News Article
{{DEFAULTSORT:Perry, George Alzheimer's disease researchers American neuroscientists Fellows of the American Association for the Advancement of Science Fellows of the Linnean Society of London Living people American people of Portuguese descent University of Texas at San Antonio faculty Allan Hancock College alumni University of California, Santa Barbara alumni People from Lompoc, California 1953 births Scripps Institution of Oceanography alumni