Genomic Health
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Genomic Health, Inc. is a company focusing on genetic research specifically in
cancer Cancer is a group of diseases involving Cell growth#Disorders, abnormal cell growth with the potential to Invasion (cancer), invade or Metastasis, spread to other parts of the body. These contrast with benign tumors, which do not spread. Po ...
detection, based out of
Redwood City, California Redwood City is a city on the San Francisco Peninsula in the San Francisco Bay Area, Bay Area of Northern California, approximately south of San Francisco and northwest of San Jose, California, San Jose. The city's population was 84,292 accor ...
. The company was acquired by and merged with Exact Sciences Corporation in 2019.


History

Genomic Health, Inc. was founded in 2000 by Randy Scott, who had previously founded and been CEO at
Incyte Incyte Corporation is an American multinational pharmaceutical company with headquarters in Wilmington, Delaware. The company currently operates manufacturing and R&D locations in North America, Europe, and Asia. Incyte Corporation currently dev ...
. He formed the company after a close friend was diagnosed with cancer and had the idea for treatment based on the specific genome of their
tumor A neoplasm () is a type of abnormal and excessive growth of tissue. The process that occurs to form or produce a neoplasm is called neoplasia. The growth of a neoplasm is uncoordinated with that of the normal surrounding tissue, and persists ...
. By 2003 Genomic Health had developed Oncotype DX, a genomic assay that quantified the likelihood of
breast cancer Breast cancer is a cancer that develops from breast tissue. Signs of breast cancer may include a Breast lump, lump in the breast, a change in breast shape, dimpling of the skin, Milk-rejection sign, milk rejection, fluid coming from the nipp ...
recurrence. This development took the company over three years and to complete and then had to convince skeptics at the time of the validity of genetic testing. In July 2005 Genomic Health filed for an
initial public offering An initial public offering (IPO) or stock launch is a public offering in which shares of a company are sold to institutional investors and usually also to retail (individual) investors. An IPO is typically underwritten by one or more investm ...
to sell up to in common stock. Investors at the time already included
Versant Ventures Versant Ventures ("Versant") is an American Venture capital firm headquartered in San Francisco, California. It is focused on making investments in the healthcare and biotechnology industries. Background In 1999 at the end of the Dot-com bu ...
and
Kleiner Perkins Caufield & Byers Kleiner Perkins, formerly Kleiner Perkins Caufield & Byers (KPCB), is an American venture capital firm which specializes in investing in incubation, early stage and growth companies. Since its founding in 1972, the firm has backed entrepreneur ...
. On it was listed on the
NASDAQ The Nasdaq Stock Market (; National Association of Securities Dealers Automated Quotations) is an American stock exchange based in New York City. It is the most active stock trading venue in the U.S. by volume, and ranked second on the list ...
with the symbol GHDX with the initial share price of for 5016722 shares. Genomic Health also started a subsidiary in 2010, Invitae, with the goal of aggregating multiple genetics tests. Invitae was spun off in 2012. The company expanded with international headquarters in
Geneva Geneva ( , ; ) ; ; . is the List of cities in Switzerland, second-most populous city in Switzerland and the most populous in French-speaking Romandy. Situated in the southwest of the country, where the Rhône exits Lake Geneva, it is the ca ...
Switzerland and UK headquarters in
London London is the Capital city, capital and List of urban areas in the United Kingdom, largest city of both England and the United Kingdom, with a population of in . London metropolitan area, Its wider metropolitan area is the largest in Wester ...
in 2011. In July 2019,
Exact Sciences The exact sciences or quantitative sciences, sometimes called the exact mathematical sciences, are those sciences "which admit of absolute precision in their results"; especially the mathematical sciences. Examples of the exact sciences are ma ...
announced that it was purchasing Genomic Health to increase the variety of medical tests they offer.


See also

*
Human genome The human genome is a complete set of nucleic acid sequences for humans, encoded as the DNA within each of the 23 distinct chromosomes in the cell nucleus. A small DNA molecule is found within individual Mitochondrial DNA, mitochondria. These ar ...
*
Genetic testing Genetic testing, also known as DNA testing, is used to identify changes in DNA sequence or chromosome structure. Genetic testing can also include measuring the results of genetic changes, such as RNA analysis as an output of gene expression, or ...


References


External links

* * {{Authority control Medical genetics Genomics companies Health care companies established in 2000 American companies established in 2000 2000 establishments in California Health care companies based in California Companies based in Redwood City, California Companies formerly listed on the Nasdaq 2005 initial public offerings 2019 mergers and acquisitions