Gene transfer agent-release holins (GTA-Hol
TC# 1.E.54 are
holins which are believed to facilitate the lysis-dependent release of a
gene transfer agent
Gene transfer agents (GTAs) are DNA-containing virus-like particles that are produced by some bacteria and archaea and mediate horizontal gene transfer. Different GTA types have originated independently from viruses in several bacterial and archae ...
. Particularly the gene transfer agent of ''
Rhodobacter capsulatus'' (RcGTA), which is known to be a bacteriophage-like genetic element that induces
horizontal gene transfer. The promoter of the RcGTA gene was identified by Westbye ''et al''. in 2013.
A representative list of members belonging to the GTA-Hol family can be found in the
Transporter Classification Database with homologues found in
Pseudomonadota
Pseudomonadota (synonym Proteobacteria) is a major phylum of Gram-negative bacteria. The renaming of phyla in 2021 remains controversial among microbiologists, many of whom continue to use the earlier names of long standing in the literature. The ...
(formerly proteobacteria) and
caudovirales.
See also
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Gene transfer agent
Gene transfer agents (GTAs) are DNA-containing virus-like particles that are produced by some bacteria and archaea and mediate horizontal gene transfer. Different GTA types have originated independently from viruses in several bacterial and archae ...
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Lysin
References
Further reading
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Holins
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