The Genain quadruplets (born in 1930) are a set of identical
quadruplet sisters. All four developed
schizophrenia
Schizophrenia () is a mental disorder characterized variously by hallucinations (typically, Auditory hallucination#Schizophrenia, hearing voices), delusions, thought disorder, disorganized thinking and behavior, and Reduced affect display, f ...
, suggesting a large
genetic component to the cause of the disease.
[ ] The pseudonym ''Genain'', used to protect the identity of the family, comes from the
Greek
Greek may refer to:
Anything of, from, or related to Greece, a country in Southern Europe:
*Greeks, an ethnic group
*Greek language, a branch of the Indo-European language family
**Proto-Greek language, the assumed last common ancestor of all kno ...
, meaning ''dire ''(αἶνος)'' birth ''(γεν-).
The sisters were given the pseudonyms Nora, Iris, Myra and Hester, to represent each of the four letters in NIMH, the acronym for the
United States
The United States of America (USA), also known as the United States (U.S.) or America, is a country primarily located in North America. It is a federal republic of 50 U.S. state, states and a federal capital district, Washington, D.C. The 48 ...
National Institute of Mental Health
The National Institute of Mental Health (NIMH) is one of 27 institutes and centers that make up the National Institutes of Health (NIH). The NIH, in turn, is an agency of the United States Department of Health and Human Services and is the primar ...
.
Nora, Iris, and Hester were hospitalized for their schizophrenia at least once each.
As of 2023, only Myra is still living.
Personal lives
The sisters were born in a midwestern American town (nicknamed "Envira") on April 14, 1930.
They were considered local celebrities due to the quadruple nature of their birth.
[ The four sisters grew up with their parents in the same household. The Genain sisters' parents were described as "disturbed".] Their paternal grandmother may have had schizophrenia with paranoid symptoms, and their father was described as abusive. Myra and Nora were probably treated more favorably by their parents, while Iris and Hester were treated more harshly. The parents considered Hester to be a "habitual masturbator" and referred to her as a "moron type" or "sex maniac". Iris and Hester were both circumcised as children in order to prevent them from masturbation.[ ] The quadruplets were reportedly physically abused by their father, given the pseudonym ''Mr. Genain''. Subsequently, the Genains accepted an offer by the NIMH
NIMH may refer to:
* Nickel–metal hydride battery (NiMH), a type of electrical battery
*National Institute of Mental Health, an agency of the United States government
* National Institute of Medical Herbalists, a professional organisation in the ...
to take the daughters into their clinic and each was diagnosed with schizophrenia.
All of the sisters except Hester graduated from high school. Myra worked as a secretary for most of her life. She married and had two sons. When she grew older, she frequently visited her sisters Nora and Hester. Her eldest son contracted AIDS
The HIV, human immunodeficiency virus (HIV) is a retrovirus that attacks the immune system. Without treatment, it can lead to a spectrum of conditions including acquired immunodeficiency syndrome (AIDS). It is a Preventive healthcare, pr ...
after a blood transfusion and died in 1996, while her younger son became a maintenance worker and retained a close relationship with his mother. Nora later managed the income the sisters received for having their photograph published in textbooks. Iris worked as a beautician for a while but most of her adult life was spent institutionalized.
Illness and scientific research
All four of the sisters developed schizophrenia by the age of 24.[ There was a history of mental illness in Mr. Genain's family that might have been an example of genetics being linked with mental illness or it may have just been a dysfunctional and abusive family free from a specific genetic component. Mr. Genain's mother had had a three-year nervous breakdown in her late teens.
]
References
Further reading
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{{DEFAULTSORT:Genain
1930 births
Living people
Sister quartets
People with schizophrenia
American people with disabilities
Quadruplets
20th-century American people
20th-century American women