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Gefapixant, sold under the brand name Lyfnua, is a medication used to treat chronic (long-term) cough. It acts as an
antagonist An antagonist is a character in a story who is presented as the main enemy or rival of the protagonist and is often depicted as a villain.P2RX3
receptor Receptor may refer to: * Sensory receptor, in physiology, any neurite structure that, on receiving environmental stimuli, produces an informative nerve impulse *Receptor (biochemistry), in biochemistry, a protein molecule that receives and respond ...
. It was authorized for medical use in the European Union in September 2023.


Medical uses

Gefapixant is
indicated In medicine, an indication is a valid reason to use a certain test, medication, procedure, or surgery. There can be multiple indications to use a procedure or medication. An indication can commonly be confused with the term diagnosis. A diagnosis ...
for the treatment of refractory or unexplained chronic cough.


Society and culture


Names

It was named in honour of Geoff Burnstock.


References

Benzosulfones Diaryl ethers Drugs developed by Merck & Co. Sulfonamides {{respiratory-system-drug-stub