Garki Project
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The Garki Project was a non-profit study conducted by the
World Health Organization The World Health Organization (WHO) is a list of specialized agencies of the United Nations, specialized agency of the United Nations which coordinates responses to international public health issues and emergencies. It is headquartered in Gen ...
from 1969 to 1976 in the Garki Local Government Area of the
Jigawa State Jigawa (; 𞤤𞤫𞤴𞤮𞤤 𞤶𞤭𞤺𞤢𞤱𞤢) is a state in Nigeria, located in the northern region of the country. Jigawa was created on 27 August 1991, under the General Ibrahim Babangida military administration. Jigawa State was ...
(then part of the
Kano State Kano (Hausa language, Hausa: ) is one of the 36 States of Nigeria, states of Nigeria, located in the Northern Region, Nigeria, northern region of the country. According to the national census done in 2006, Kano State is the List of Nigerian st ...
),
Nigeria Nigeria, officially the Federal Republic of Nigeria, is a country in West Africa. It is situated between the Sahel to the north and the Gulf of Guinea in the Atlantic Ocean to the south. It covers an area of . With Demographics of Nigeria, ...
. Its purpose was to study
epidemiology Epidemiology is the study and analysis of the distribution (who, when, and where), patterns and Risk factor (epidemiology), determinants of health and disease conditions in a defined population, and application of this knowledge to prevent dise ...
and control of
malaria Malaria is a Mosquito-borne disease, mosquito-borne infectious disease that affects vertebrates and ''Anopheles'' mosquitoes. Human malaria causes Signs and symptoms, symptoms that typically include fever, Fatigue (medical), fatigue, vomitin ...
in the lowland rural
Sudan Sudan, officially the Republic of the Sudan, is a country in Northeast Africa. It borders the Central African Republic to the southwest, Chad to the west, Libya to the northwest, Egypt to the north, the Red Sea to the east, Eritrea and Ethiopi ...
savanna A savanna or savannah is a mixed woodland-grassland (i.e. grassy woodland) biome and ecosystem characterised by the trees being sufficiently widely spaced so that the canopy does not close. The open canopy allows sufficient light to reach th ...
in northern Nigeria. The main objectives of the project were to measure the effects of
indoor residual spraying Indoor residual spraying or IRS is the process of spraying the inside of dwellings with an insecticide to kill mosquitoes that spread malaria. A dilute solution of insecticide is sprayed on the inside walls of certain types of dwellings—those w ...
and
mass drug administration The administration of drugs to whole populations irrespective of disease status is referred to as mass drug administration (MDA) or mass dispensing. This article describes the administration of antimalarial drugs to whole populations, an interven ...
and to construct and test a
mathematical model A mathematical model is an abstract and concrete, abstract description of a concrete system using mathematics, mathematical concepts and language of mathematics, language. The process of developing a mathematical model is termed ''mathematical m ...
of malaria transmission. The project was funded by both the World Health Organization and the Federal Government of Nigeria. The project concluded that indoor spraying with
Propoxur Propoxur (Baygon) is a carbamate non-systemic insecticide, produced from catechol, and was introduced in 1959. It has a fast knockdown and long residual effect, and is used against turf, forestry, and household pests and fleas. It is also used in ...
had a very limited impact on malaria and the mass administration of sulfalene-pyrimethamine (in combination with the residual spraying) failed to interrupt the transmission of malaria for any length of time. However, the mathematical model used was found to simulate the epidemiology of
Plasmodium falciparum ''Plasmodium falciparum'' is a Unicellular organism, unicellular protozoan parasite of humans and is the deadliest species of ''Plasmodium'' that causes malaria in humans. The parasite is transmitted through the bite of a female ''Anopheles'' mos ...
fairly realistically and was considered fit for use in planning control of malaria.


References


External links


The Garki Project book
in pdf chapters from WHO

with references to the Garki project and data

{{Webarchive, url=https://web.archive.org/web/20190817131032/http://garkiproject.nd.edu/welcome-garki-project.html , date=2019-08-17 also has references and data. Malaria organizations Jigawa State Medical and health organizations based in Nigeria