Gardiquimod is an experimental drug which acts selectively at both mouse and human forms of
toll-like receptor 7 (TLR7). It functions as an immune response modifier.
The core structure is 1''H''-imidazo
,5-cuinoline, as found in related drugs such as
imiquimod
Imiquimod, sold under the brand name Aldara among others, is a medication that acts as an immune response modifier that is used to treat genital warts, superficial basal cell carcinoma, and actinic keratosis.
Scientists at 3M's pharmaceutica ...
and
resiquimod
Resiquimod (R-848) is a drug that acts as an immune response modifier, and has antiviral and antitumour activity. It is used as a topical gel in the treatment of skin lesions such as those caused by the herpes simplex virus and cutaneous T cell l ...
. It is structurally very similar to resiquimod differing only by an oxygen for nitrogen switch.
References
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Antineoplastic and immunomodulating drugs
Imidazoquinolines
Tertiary alcohols
Experimental drugs