Gap junction Gap junctions are membrane channels between adjacent cells that allow the direct exchange of cytoplasmic substances, such small molecules, substrates, and metabolites. Gap junctions were first described as ''close appositions'' alongside tight ...

protein Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residue (biochemistry), residues. Proteins perform a vast array of functions within organisms, including Enzyme catalysis, catalysing metab ...

s ;Gap junction α (GJA) proteins *

GJA1 Gap junction alpha-1 protein (GJA1), also known as connexin 43 (Cx43), is a protein that in humans is encoded by the ''GJA1'' gene on chromosome 6. As a connexin, GJA1 is a component of gap junctions, which allow for gap junction intercellular ...

, Cx43, gap junction alpha-1 protein * GJA2, Cx38, gap junction alpha-2 protein *

GJA3 Gap junction alpha-3 protein is a protein that in humans is encoded by the ''GJA3'' gene. Interactions GJA3 has been shown to interact with Tight junction protein 1 Tight junction protein ZO-1 also known as Zonula Occludens-1 (ZO-1), is a 2 ...

, Cx46, gap junction alpha-3 protein * GJA4, Cx37, gap junction alpha-4 protein * GJA5, Cx40, gap junction alpha-5 protein * GJA6, Cx33 gap junction alpha-6 protein * GJA7, Cx44.3-45.6, gap junction alpha-7 protein *

GJA8 Gap junction alpha-8 protein is a protein that in humans is encoded by the ''GJA8'' gene In biology, the word gene has two meanings. The Mendelian gene is a basic unit of heredity. The molecular gene is a sequence of nucleotides in DNA tha ...

, Cx50, gap junction alpha-8 protein * GJA9, Cx58, gap junction alpha-9 protein * GJA10, Cx62, gap junction alpha-10 protein * GJA11, Cx59, gap junction alpha-11 protein * GJA12, Cx46.6, gap junction alpha-12 protein ;Gap junction β (GJB) proteins * GJB1, Cx32, gap junction beta-1 protein *

GJB2 Gap junction beta-2 protein (GJB2), also known as connexin 26 (Cx26) — is a protein that in humans is encoded by the ''GJB2'' gene. Function Gap junctions were first characterized by electron microscopy as regionally specialized structure ...

, Cx26, gap junction beta-2 protein * GJB3, Cx31, gap junction beta-3 protein * GJB4, Cx30.3, gap junction beta-4 protein * GJB5, Cx31.1, gap junction beta-5 protein *

GJB6 Gap junction beta-6 protein (GJB6), also known as connexin 30 (Cx30) — is a protein that in humans is encoded by the ''GJB6'' gene. Connexin 30 (Cx30) is one of several gap junction proteins expressed in the inner ear. Mutations in gap juncti ...

, Cx30, gap junction beta-6 protein * GJB7, Cx25, gap junction beta-7 protein ;Gap junction γ (GJC) proteins * GJC1, Cx45.6, gap junction gamma-1 protein * GJC2, Cx47, gap junction gamma-2 protein * GJC3, Cx29, gap junction gamma-3 protein ;Gap junction δ (GJD) proteins * GJD1, Cx29, gap junction delta-1 protein * GJD2, Cx36, gap junction delta-2 protein * GJD3, Cx31.9, gap junction delta-3 protein * GJD4, Cx40.1, gap junction delta-4 protein ;Gap junction ε (GJE) proteins * GJE1, Cx23, gap junction epsilon-1 protein

See also