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Gap junction Gap junctions are specialized intercellular connections between a multitude of animal cell-types. They directly connect the cytoplasm of two cells, which allows various molecules, ions and electrical impulses to directly pass through a regula ...
protein Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, respon ...
s ;Gap junction α (GJA) proteins *
GJA1 Gap junction alpha-1 protein (GJA1), also known as connexin 43 (Cx43), is a protein that in humans is encoded by the ''GJA1'' gene on chromosome 6. As a connexin, GJA1 is a component of gap junctions, which allow for gap junction intercellular ...
, gap junction alpha-1 protein *
GJA2 GJA may refer to: * Ghana Journalists Association * Globe Jet, a defunct Lebanese airline * Golden Joystick Awards * Guanaja Airport, in Honduras * Gojra railway station Gojra railway station ( ur, ) is located in Gojra city, Toba Tek Singh ...
, gap junction alpha-2 protein *
GJA3 Gap junction alpha-3 protein is a protein that in humans is encoded by the ''GJA3'' gene. Interactions GJA3 has been shown to interact with Tight junction protein 1 Zonula occludens-1 ZO-1, also known as Tight junction protein-1 is a 220-kD per ...
, gap junction alpha-3 protein *
GJA4 Gap junction alpha-4 protein, also known as Connexin-37 or Cx37, is a protein that in humans is encoded by the ''GJA4'' gene. This protein, like other Connexin proteins, forms connections between cells known as gap junctions. Connexin 37 can be f ...
, gap junction alpha-4 protein *
GJA5 Gap junction alpha-5 protein (GJA5), also known as connexin 40 (Cx40) — is a protein that in humans is encoded by the ''GJA5'' gene. Function This gene is a member of the connexin gene family. The encoded protein is a component of gap junct ...
, gap junction alpha-5 protein * GJA6, gap junction alpha-6 protein *
GJA7 Gap junction gamma-1 protein (GJC1), also known as gap junction alpha-7 protein (GJA7) and connexin 45 (Cx45) — is a protein that in humans is encoded by the ''GJC1'' gene. Function This gene is a member of the connexin gene family. The enco ...
, gap junction alpha-7 protein *
GJA8 Gap junction alpha-8 protein is a protein that in humans is encoded by the ''GJA8'' gene. It is also known as connexin 50. Related gene problems * 1q21.1 deletion syndrome * 1q21.1 duplication syndrome *microphthalmia and other vision pathologi ...
, gap junction alpha-8 protein *
GJA9 Gap junction delta-2 protein (GJD2) also known as connexin-36 (Cx36) or gap junction alpha-9 protein (GJA9) is a protein that in humans is encoded by the ''GJD2'' gene. Function GJD2, also called connexin-36 (CX36), is a member of the connexi ...
, gap junction alpha-9 protein *
GJA10 Gap junction alpha-10 protein, also known as connexin-62 (Cx62), is a protein that in humans is encoded by the GJA10 gene. Connexins, such as GJA10, are involved in the formation of gap junction Gap junctions are specialized intercellular ...
, gap junction alpha-10 protein * GJA11, gap junction alpha-11 protein * GJA12, gap junction alpha-12 protein ;Gap junction β (GJB) proteins *
GJB1 Gap junction beta-1 protein (GJB1), also known as connexin 32 (Cx32) is a transmembrane protein that in humans is encoded by the ''GJB1'' gene. Gap junction beta-1 protein is a member of the gap junction connexin family of proteins that regulates ...
, gap junction beta-1 protein *
GJB2 Gap junction beta-2 protein (GJB2), also known as connexin 26 (Cx26) — is a protein that in humans is encoded by the ''GJB2'' gene. Clinical significance Defects in this gene lead to the most common form of congenital deafness in developed ...
, gap junction beta-2 protein *
GJB3 Gap junction beta-3 protein (GJB3), also known as connexin 31 (Cx31) — is a protein that in humans is encoded by the ''GJB3'' gene. Function This gene is a member of the connexin gene family. The encoded protein is a component of gap junctio ...
, gap junction beta-3 protein *
GJB4 Gap junction beta-4 protein (GJB4), also known as connexin 30.3 (Cx30.3) — is a protein that in humans is encoded by the ''GJB4'' gene. References Further reading

* * * * * * * * * * * * * {{gene-1-stub Connexins ...
, gap junction beta-4 protein *
GJB5 Gap junction beta-5 protein (GJB5), also known as connexin-31.1 (Cx31.1), is a protein that in humans is encoded by the ''GJB5'' gene. Function Gap junctions are conduits that allow the direct cell-to-cell passage of small cytoplasmic molecule ...
, gap junction beta-5 protein *
GJB6 Gap junction beta-6 protein (GJB6), also known as connexin 30 (Cx30) — is a protein that in humans is encoded by the ''GJB6'' gene. Connexin 30 (Cx30) is one of several gap junction proteins expressed in the inner ear. Mutations in gap junction ...
, gap junction beta-6 protein *
GJB7 Gap junction beta-7 protein (GJB7), also known as connexin-25 (Cx25), is a protein that in humans is encoded by the ''GJB7'' gene. Function Connexin Connexins (Cx)TC# 1.A.24, or gap junction proteins, are structurally related transmembrane p ...
, gap junction beta-7 protein ;Gap junction γ (GJC) proteins * GJC1, gap junction gamma-1 protein * GJC2, gap junction gamma-2 protein * GJC3, gap junction gamma-3 protein ;Gap junction δ (GJD) proteins * GJD1, gap junction delta-1 protein *
GJD2 Gap junction delta-2 protein (GJD2) also known as connexin-36 (Cx36) or gap junction alpha-9 protein (GJA9) is a protein that in humans is encoded by the ''GJD2'' gene. Function GJD2, also called connexin-36 (CX36), is a member of the connexi ...
, gap junction delta-2 protein *
GJD3 Gap junction delta-2 (GJD2), also known as connexin-36 (Cx36) or gap junction alpha-9 (GJA9), is a protein that in humans is encoded by the ''GJD2'' gene. Function This gene is a member of the large family of connexins that are required for th ...
, gap junction delta-3 protein * GJD4, gap junction delta-4 protein


See also

* Tight junction protein {{SIA