The COP9 signalosome complex subunit 1 is a
protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residue (biochemistry), residues. Proteins perform a vast array of functions within organisms, including Enzyme catalysis, catalysing metab ...
encoded by the ''GPS1''
gene
In biology, the word gene has two meanings. The Mendelian gene is a basic unit of heredity. The molecular gene is a sequence of nucleotides in DNA that is transcribed to produce a functional RNA. There are two types of molecular genes: protei ...
.
This gene is known to inhibit G-protein and mitogen-activated signal transduction in mammalian cells. The protein encoded by this gene shares significant similarity with Arabidopsis FUS6, a regulator of light-mediated signal transduction in plant cells. Two alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.
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