Friedrich Wegener
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Friedrich Wegener (7 April 1907,
Varel Varel () is a town in the district of Friesland, in Lower Saxony, Germany. It is situated near the Jade River and the Jade Bight, approximately south of Wilhelmshaven and north of Oldenburg. With a population of 23,984 (2020) it is the bigg ...
– 9 July 1990,
Lübeck Lübeck (; or ; Latin: ), officially the Hanseatic League, Hanseatic City of Lübeck (), is a city in Northern Germany. With around 220,000 inhabitants, it is the second-largest city on the German Baltic Sea, Baltic coast and the second-larg ...
, ) was a German
pathologist Pathology is the study of disease. The word ''pathology'' also refers to the study of disease in general, incorporating a wide range of biology research fields and medical practices. However, when used in the context of modern medical treatme ...
who is notable for being a high-ranking Nazi physician and for his description of a
rare disease A rare disease is any disease that affects a small percentage of the population. In some parts of the world, the term orphan disease describes a rare disease whose rarity results in little or no funding or research for treatments, without financi ...
originally referred to Wegener disease and now referred to as
granulomatosis with polyangiitis Granulomatosis with polyangiitis (GPA), formerly known as Wegener's granulomatosis (WG), after Nazi German physician Friedrich Wegener, is a rare, long-term, systemic disorder that involves the formation of granulomas and vasculitis, inflammatio ...
. Although this disease was known before Wegener's description, from the 1950s onwards it was generally referred to as Wegener's granulomatosis.


Biography


Early life

Friedrich Wegener was born on 7 April 1907 in Varel, Oldenburg, Germany. His father was a doctor and his mother a Swedish gymnastic director.


World War II era

More detail about aspects of Wegener's biography during the Nazi regime first became available in 2006. Wegener joined the
Nazi Party The Nazi Party, officially the National Socialist German Workers' Party ( or NSDAP), was a far-right politics, far-right political party in Germany active between 1920 and 1945 that created and supported the ideology of Nazism. Its precursor ...
in 1932. Specifically, he was a member of the
Sturmabteilung The (; SA; or 'Storm Troopers') was the original paramilitary organisation under Adolf Hitler and the Nazi Party of Germany. It played a significant role in Adolf Hitler's rise to power, Hitler's rise to power in the 1920s and early 1930s. I ...
, a paramilitary branch of the Nazi party that participated in violent conflicts. As a relatively high-ranking military physician, he spent some of
World War II World War II or the Second World War (1 September 1939 – 2 September 1945) was a World war, global conflict between two coalitions: the Allies of World War II, Allies and the Axis powers. World War II by country, Nearly all of the wo ...
in a medical office three blocks from the
Łódź Ghetto The Łódź Ghetto or Litzmannstadt Ghetto (after the Nazi German name for Łódź) was a Nazi ghetto established by the German authorities for Polish Jews and Roma following the Invasion of Poland. It was the second-largest ghetto in all of ...
, a Jewish ghetto in
Łódź Łódź is a city in central Poland and a former industrial centre. It is the capital of Łódź Voivodeship, and is located south-west of Warsaw. Łódź has a population of 655,279, making it the country's List of cities and towns in Polan ...
,
Poland Poland, officially the Republic of Poland, is a country in Central Europe. It extends from the Baltic Sea in the north to the Sudetes and Carpathian Mountains in the south, bordered by Lithuania and Russia to the northeast, Belarus and Ukrai ...
. He conducted
autopsies An autopsy (also referred to as post-mortem examination, obduction, necropsy, or autopsia cadaverum) is a surgical procedure that consists of a thorough examination of a corpse by dissection to determine the cause, mode, and manner of death; ...
on
Jewish Jews (, , ), or the Jewish people, are an ethnoreligious group and nation, originating from the Israelites of History of ancient Israel and Judah, ancient Israel and Judah. They also traditionally adhere to Judaism. Jewish ethnicity, rel ...
concentration camp A concentration camp is a prison or other facility used for the internment of political prisoners or politically targeted demographics, such as members of national or ethnic minority groups, on the grounds of national security, or for exploitati ...
inmates and the facility he worked in performed experiments on prisoners. There is no direct evidence of active participation of Wegener in these human experiments, but it is likely he was aware of them. The
United Nations War Crimes Commission The United Nations War Crimes Commission (UNWCC), initially the United Nations Commission for the Investigation of War Crimes, was a United Nations body that aided the prosecution of war crimes committed by Nazi Germany and other Axis powers duri ...
had a legal mandate against Friedrich Wegener and the Polish Institute for the Prosecution of German War Crimes confirmed that he had appeared on the central list of war criminal and security suspects. Wegener was released without a trial as no charges were brought against him. In an editorial in 2006 the evidence was regarded as “thin but tangible."


Medical contributions

In 1936, Friedrich Wegener described the disease that once bore his name, Wegener disease, as a systemic disorder characterized by aseptic vasculitis granulomatous inflammation and vasculitis which affects the upper and lower respiratory tracts and the kidneys. Granulomatosis with Polyangiitis is a relatively rare disorder, occurring in 1/25,000 persons.Non-neoplastic Disorders of the Lower Respiratory Tract. by William D Travis. Publisher: Washington, DC American Registry of Pathology 2002 After revelations about his Nazi Party past became common knowledge, the disease has been referred to as Granulomatosis with Polyangiitis (GPA). The
American College of Chest Physicians The American College of Chest Physicians (CHEST) is a medical association in the United States consisting of physicians and non-physician specialists in the field of chest medicine, which includes pulmonology, critical care medicine Intensiv ...
(ACCP) awarded Wegener a “master clinician” prize in 1989. After his Nazi past was discovered in 2000, the ACCP rescinded the prize and campaigned to rename Wegener's granulomatosis to ANCA-associated granulomatous vasculitis. More recently, several professional societies, including the
American College of Rheumatology The American College of Rheumatology (ACR; until 1985 called American Rheumatism Association) is an organization of and for physicians, health professionals, and scientists that advances rheumatology through programs of education, research, advocac ...
, the European League Against Rheumatism, and the
American Society of Nephrology Founded in 1966, the American Society of Nephrology (ASN) is the world's largest professional society devoted to the study of kidney disease. Composed of over 20,000 physicians and scientists, ASN promotes expert patient care, advances medical r ...
, proposed the name 'granulomatosis with polyangiitis' in a 2011 editorial. The new name for the condition is now widely adopted in the scientific literature and by institutions and charities.


See also

*
List of medical eponyms with Nazi associations An eponym is a phrase that is derived from or based on a person's name. Medical conditions are often named after the person who first described the disorder and can also be named after the first person in whom the disorder presented or the area i ...


References


Further reading

* * * Grzybowski A, Rohrbach JM (2011)Should we abandon the eponym 'Wegener's granulomatosis'? A historical excursion (Letter to the editor). Retina 31, 1439-1442 {{DEFAULTSORT:Wegener, Friedrich 1907 births 1990 deaths People from Varel People from the Grand Duchy of Oldenburg German pathologists Physicians in the Nazi Party Academic staff of the University of Kiel