Frank S. Walsh (born 1953 in

Wishaw Wishaw (; ; ) is a large town in North Lanarkshire, Scotland, on the edge of the River Clyde, Clyde Valley, south-east of Glasgow city centre. The town is part of the Motherwell and Wishaw (UK Parliament constituency), Motherwell and Wishaw c ...

North Lanarkshire North Lanarkshire (; ) is one of the 32 council areas of Scotland. It borders the north-east of the Glasgow City council area and contains many of Glasgow's suburbs, commuter towns, and villages. It also borders East Dunbartonshire, Falkirk (co ...

) is a British-born

neuroscientist A neuroscientist (or neurobiologist) is a scientist specializing in neuroscience that deals with the anatomy and function of neurons, Biological neural network, neural circuits, and glia, and their Behavior, behavioral, biological, and psycholo ...

. He is best known for his work on the understanding of the role of

cell adhesion molecules Cell adhesion molecules (CAMs) are a subset of cell surface proteins that are involved in the binding of cells with other cells or with the extracellular matrix (ECM), in a process called cell adhesion. In essence, CAMs help cells stick to each ...

in the development and regeneration of the

nervous system In biology, the nervous system is the complex system, highly complex part of an animal that coordinates its behavior, actions and sense, sensory information by transmitting action potential, signals to and from different parts of its body. Th ...

. He is the author of over 250 publications in peer-reviewed journals. In 2008 he was made a Corresponding Fellow of the

Royal Society of Edinburgh The Royal Society of Edinburgh (RSE) is Scotland's national academy of science and letters. It is a registered charity that operates on a wholly independent and non-partisan basis and provides public benefit throughout Scotland. It was establis ...

, and in 2007 became a Fellow of

King's College London King's College London (informally King's or KCL) is a public university, public research university in London, England. King's was established by royal charter in 1829 under the patronage of George IV of the United Kingdom, King George IV ...

. He has also received honorary degrees from the Universities of

Perugia Perugia ( , ; ; ) is the capital city of Umbria in central Italy, crossed by the River Tiber. The city is located about north of Rome and southeast of Florence. It covers a high hilltop and part of the valleys around the area. It has 162,467 ...

and

Bologna Bologna ( , , ; ; ) is the capital and largest city of the Emilia-Romagna region in northern Italy. It is the List of cities in Italy, seventh most populous city in Italy, with about 400,000 inhabitants and 150 different nationalities. Its M ...

in Italy, and the

University of Strathclyde The University of Strathclyde () is a public research university located in Glasgow, Scotland. Founded in 1796 as the Andersonian Institute, it is Glasgow's second-oldest university, having received its royal charter in 1964 as the first techn ...

and University of Dundee in Scotland. Walsh started his scientific career with an undergraduate degree in

biochemistry Biochemistry, or biological chemistry, is the study of chemical processes within and relating to living organisms. A sub-discipline of both chemistry and biology, biochemistry may be divided into three fields: structural biology, enzymology, a ...

from the University of Strathclyde (1974)and a subsequent PhD in biochemistry from University College London with the research being carried out at the MRC National Institute for Medical Research(1977). His post-doctoral training was conducted under the tutelage of the Nobel prize winner

Marshall Nirenberg Marshall Warren Nirenberg (April 10, 1927 – January 15, 2010) was an American biochemist and geneticist. He shared a Nobel Prize in Physiology or Medicine in 1968 with Har Gobind Khorana and Robert W. Holley for "breaking the genetic code" a ...

at the

NIH The National Institutes of Health (NIH) is the primary agency of the United States government responsible for biomedical and public health research. It was founded in 1887 and is part of the United States Department of Health and Human Service ...

Bethesda, Maryland Bethesda () is an unincorporated, census-designated place in southern Montgomery County, Maryland, United States. Located just northwest of Washington, D.C., it is a major business and government center of the Washington metropolitan region ...

, USA (1977–79). From 2002 to 2009 he was executive vice president of discovery research at Wyeth, a leading pharmaceutical company in Collegeville Pennsylvania, US. In this role he has been responsible for overseeing the transition of more than 80 novel drug candidates into clinical development for a number of devastating diseases such as

Alzheimer's disease Alzheimer's disease (AD) is a neurodegenerative disease and the cause of 60–70% of cases of dementia. The most common early symptom is difficulty in remembering recent events. As the disease advances, symptoms can include problems wit ...

, stroke,

schizophrenia Schizophrenia () is a mental disorder characterized variously by hallucinations (typically, Auditory hallucination#Schizophrenia, hearing voices), delusions, thought disorder, disorganized thinking and behavior, and Reduced affect display, f ...

, cancer,

diabetes Diabetes mellitus, commonly known as diabetes, is a group of common endocrine diseases characterized by sustained high blood sugar levels. Diabetes is due to either the pancreas not producing enough of the hormone insulin, or the cells of th ...

osteoarthritis Osteoarthritis is a type of degenerative joint disease that results from breakdown of articular cartilage, joint cartilage and underlying bone. A form of arthritis, it is believed to be the fourth leading cause of disability in the world, affect ...

rheumatoid arthritis Rheumatoid arthritis (RA) is a long-term autoimmune disorder that primarily affects synovial joint, joints. It typically results in warm, swollen, and painful joints. Pain and stiffness often worsen following rest. Most commonly, the wrist and h ...

and

COPD Chronic obstructive pulmonary disease (COPD) is a type of progressive lung disease characterized by chronic respiratory symptoms and airflow limitation. GOLD defines COPD as a heterogeneous lung condition characterized by chronic respiratory s ...

. In 2012 he formed a new biotechnology company called Ossianix to develop biological therapeutics for serious diseases of the brain and other organ systems. www.ossianix.com. The company is based in Philadelphia, US, and Stevenage, UK. He was Sir William Dunn Professor and head of experimental pathology at the United Medical and Dental Schools from 1989, and research dean from 1994 until 1997 when he joined

SmithKline Beecham GSK plc (an acronym from its former name GlaxoSmithKline plc) is a British multinational pharmaceutical and biotechnology company with headquarters in London. It was established in 2000 by a merger of Glaxo Wellcome and SmithKline Beecham, w ...

as vice president of

neuroscience Neuroscience is the scientific study of the nervous system (the brain, spinal cord, and peripheral nervous system), its functions, and its disorders. It is a multidisciplinary science that combines physiology, anatomy, molecular biology, ...

research. With the creation of

GlaxoSmithKline GSK plc (an acronym from its former name GlaxoSmithKline plc) is a British Multinational corporation, multinational Pharmaceutics, pharmaceutical and biotechnology company with headquarters in London. It was established in 2000 by a Mergers an ...

from the merger of SmithKline Beecham and Glaxo Wellcome, he became senior vice president and head of the company's Neurology-Centre of Excellence for Drug Discovery. In addition to his corporate roles, he holds visiting professorships at

, the

University College Dublin University College Dublin (), commonly referred to as UCD, is a public research university in Dublin, Ireland, and a collegiate university, member institution of the National University of Ireland. With 38,417 students, it is Ireland's largest ...

, and was elected to the

Academy of Medical Sciences The Academy of Medical Sciences is an organisation established in the UK in 1998. It is one of the four UK National Academy, National Academies, the others being the British Academy, the Royal Academy of Engineering and the Royal Society. Its ...

(London) in 2003. In addition, he has been chairman of the

Muscular Dystrophy Muscular dystrophies (MD) are a genetically and clinically heterogeneous group of rare neuromuscular diseases that cause progressive weakness and breakdown of skeletal muscles over time. The disorders differ as to which muscles are primarily affe ...

Campaign research committee, a Trustee of Spinal Research, a visiting examiner at

, an adviser to the college's MRC Centre for Developmental Neurobiology and a special advisor to the Wolfson Centre for Age-Related Diseases. He was also joint editor-in-chief of the journal '' Molecular and Cellular Neuroscience''.Elsevier: ''Molecular and Cellular Neuroscience'': Editorial Board
(accessed 6 January 2009)

References

{{DEFAULTSORT:Walsh, Frank S 1953 births Living people British neuroscientists University of Perugia alumni University of Bologna alumni Fellows of the Royal Society of Edinburgh Fellows of the Academy of Medical Sciences (United Kingdom) People from Wishaw Academics of King's College London Fellows of King's College London