Frank Lappin Horsfall, Jr. (

Seattle Seattle ( ) is the most populous city in the U.S. state of Washington and in the Pacific Northwest region of North America. With a population of 780,995 in 2024, it is the 18th-most populous city in the United States. The city is the cou ...

, December 14, 1906 –

New York City New York, often called New York City (NYC), is the most populous city in the United States, located at the southern tip of New York State on one of the world's largest natural harbors. The city comprises five boroughs, each coextensive w ...

, February 19, 1971) was an American microbiologist specializing in pathology. He worked at the Rockefeller Institute, New York, from 1934 to 1960 and in the early 1950s ran the Virology Laboratory there. The

Tamm–Horsfall protein Uromodulin (UMOD),Tamm-Horsfall protein (THP), is a zona pellucida-like domain-containing glycoprotein that in humans is encoded by the ''UMOD'' gene. Uromodulin is the most abundant protein excreted in ordinary urine. The human UMOD gene is l ...

was first purified in 1952 during his work with Igor Tamm. He was elected in 1948 a member of the

United States National Academy of Sciences The National Academy of Sciences (NAS) is a United States nonprofit, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the Nati ...

. He was later elected to the

American Philosophical Society The American Philosophical Society (APS) is an American scholarly organization and learned society founded in 1743 in Philadelphia that promotes knowledge in the humanities and natural sciences through research, professional meetings, publicat ...

in 1956 and the

American Academy of Arts and Sciences The American Academy of Arts and Sciences (The Academy) is one of the oldest learned societies in the United States. It was founded in 1780 during the American Revolution by John Adams, John Hancock, James Bowdoin, Andrew Oliver, and other ...

in 1967. He was the president of the

American Association of Immunologists American(s) may refer to: * American, something of, from, or related to the United States of America, commonly known as the "United States" or "America" ** Americans, citizens and nationals of the United States of America ** American ancestry, p ...

for the academic year 1967–1968. A collection of his papers is held at the National Library of Medicine.

References

* ''Who Was Who in America: with World Notables. 1969–1973'' (), Marquis Who's Who, 1973
"Frank Lappin Horsfall, Jr."
by George K. Hirst 1906 births 1971 deaths American pathologists Physicians from Seattle University of Washington alumni McGill University alumni Members of the United States National Academy of Sciences {{US-physician-stub Members of the American Philosophical Society