Fosdevirine is an experimental antiviral agent of the
non-nucleoside reverse transcriptase inhibitor
Reverse-transcriptase inhibitors (RTIs) are a class of antiretroviral drugs used to treat HIV infection or AIDS, and in some cases hepatitis B. RTIs inhibit activity of reverse transcriptase, a viral DNA polymerase that is required for replication ...
class that was studied for potential use in the treatment of
HIV-AIDS.
It was discovered by Idenix Pharmaceuticals and was being developed by
GlaxoSmithKline
GSK plc, formerly GlaxoSmithKline plc, is a British multinational pharmaceutical and biotechnology company with global headquarters in London, England. Established in 2000 by a merger of Glaxo Wellcome and SmithKline Beecham. GSK is the ten ...
and
ViiV Healthcare, but it has now been discontinued due to unexpected side effects.
References
{{Antiinfective-drug-stub
Non-nucleoside reverse transcriptase inhibitors
Indoles
Nitriles
Chloroarenes
Phosphinates
Abandoned drugs