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A food contaminant is a harmful chemical or
microorganism A microorganism, or microbe, is an organism of microscopic scale, microscopic size, which may exist in its unicellular organism, single-celled form or as a Colony (biology)#Microbial colonies, colony of cells. The possible existence of unseen ...
present in food, which can cause illness to the consumer. The impact of chemical contaminants on consumer health and well-being is often apparent only after many years of processing and prolonged exposure at low levels (e.g., 
cancer Cancer is a group of diseases involving Cell growth#Disorders, abnormal cell growth with the potential to Invasion (cancer), invade or Metastasis, spread to other parts of the body. These contrast with benign tumors, which do not spread. Po ...
). Unlike food-borne pathogens, chemical contaminants present in foods are often unaffected by thermal processing. Chemical contaminants can be classified according to the source of contamination and the mechanism by which they enter the food product.


Agrochemicals

Agrochemicals are chemicals used in agricultural practices and animal husbandry with the intent to increase crop yields. Such agents include
pesticides Pesticides are substances that are used to pest control, control pest (organism), pests. They include herbicides, insecticides, nematicides, fungicides, and many others (see table). The most common of these are herbicides, which account for a ...
(e.g.,  insecticides, herbicides, rodenticides), plant growth regulators, veterinary drugs (e.g.,  nitrofuran, fluoroquinolones, malachite green, chloramphenicol), and bovine somatotropin ( rBST).


Environmental contaminants

Environmental contaminants are chemicals that are present in the environment in which the food is grown, harvested, transported, stored, packaged, processed, and consumed. The physical contact of the food with its environment results in its contamination. Possible sources of contamination and contaminants common to that vector include: * Air: radionuclides ( caesium-137, strontium-90), polycyclic aromatic hydrocarbons (PAH) * Water:
arsenic Arsenic is a chemical element; it has Symbol (chemistry), symbol As and atomic number 33. It is a metalloid and one of the pnictogens, and therefore shares many properties with its group 15 neighbors phosphorus and antimony. Arsenic is not ...
, mercury * Soil: cadmium,
nitrate Nitrate is a polyatomic ion with the chemical formula . salt (chemistry), Salts containing this ion are called nitrates. Nitrates are common components of fertilizers and explosives. Almost all inorganic nitrates are solubility, soluble in wa ...
s, perchlorates * Packaging materials:
antimony Antimony is a chemical element; it has chemical symbol, symbol Sb () and atomic number 51. A lustrous grey metal or metalloid, it is found in nature mainly as the sulfide mineral stibnite (). Antimony compounds have been known since ancient t ...
, tin,
lead Lead () is a chemical element; it has Chemical symbol, symbol Pb (from Latin ) and atomic number 82. It is a Heavy metal (elements), heavy metal that is density, denser than most common materials. Lead is Mohs scale, soft and Ductility, malleabl ...
, perfluorooctanoic acid (PFOA), semicarbazide, benzophenone, isopropylthioxanthone (ITX),
bisphenol A Bisphenol A (BPA) is a chemical compound primarily used in the manufacturing of various plastics. It is a colourless solid which is Solubility, soluble in most common organic solvents, but has very poor solubility in water. BPA is produced on a ...
* Processing/cooking equipment:
copper Copper is a chemical element; it has symbol Cu (from Latin ) and atomic number 29. It is a soft, malleable, and ductile metal with very high thermal and electrical conductivity. A freshly exposed surface of pure copper has a pinkish-orang ...
or other metal chips, lubricants, cleaning and sanitizing agents * Naturally occurring toxins: mycotoxins, phytohemagglutinin, pyrrolizidine alkaloids, grayanotoxin, scombrotoxin (
histamine Histamine is an organic nitrogenous compound involved in local immune responses communication, as well as regulating physiological functions in the gut and acting as a neurotransmitter for the brain, spinal cord, and uterus. Discovered in 19 ...
), ciguatera, shellfish toxins (see shellfish poisoning),
tetrodotoxin Tetrodotoxin (TTX) is a potent neurotoxin. Its name derives from Tetraodontiformes, an Order (biology), order that includes Tetraodontidae, pufferfish, porcupinefish, ocean sunfish, and triggerfish; several of these species carry the toxin. Alt ...
, among many others.


Pesticides and carcinogens

There are many cases of banned pesticides or carcinogens found in foods. *
Greenpeace Greenpeace is an independent global campaigning network, founded in Canada in 1971 by a group of Environmental movement, environmental activists. Greenpeace states its goal is to "ensure the ability of the Earth to nurture life in all its biod ...
exposed in 2006 that 25% of surveyed supermarkets in China stocked agricultural products contaminated with banned pesticides. Over 70% of tomatoes that tested were found to have the banned pesticide Lindane, and almost 40% of the samples had a mix of three or more types of pesticides. Tangerine,
strawberry The garden strawberry (or simply strawberry; ''Fragaria × ananassa'') is a widely grown Hybrid (biology), hybrid plant cultivated worldwide for its fruit. The genus ''Fragaria'', the strawberries, is in the rose family, Rosaceae. The fruit ...
, and Kyofung
grape A grape is a fruit, botanically a berry, of the deciduous woody vines of the flowering plant genus ''Vitis''. Grapes are a non- climacteric type of fruit, generally occurring in clusters. The cultivation of grapes began approximately 8,0 ...
samples were also found contaminated by banned pesticides, including the highly toxic methamidophos. Greenpeace says there exists no comprehensive monitoring on fruit produce in the Hong Kong as of 2006. * In India, soft drinks were found contaminated with high levels of pesticides and insecticides, including lindane, DDT, malathion and chlorpyrifos. * Formaldehyde, a
carcinogen A carcinogen () is any agent that promotes the development of cancer. Carcinogens can include synthetic chemicals, naturally occurring substances, physical agents such as ionizing and non-ionizing radiation, and biologic agents such as viruse ...
, was frequently found in the common Vietnamese dish, Pho, resulting in the 2007 Vietnam food scare. "Health agencies have known that Vietnamese
soy sauce Soy sauce (sometimes called soya sauce in British English) is a liquid condiment of China, Chinese origin, traditionally made from a fermentation (food), fermented paste of soybeans, roasted cereal, grain, brine, and ''Aspergillus oryzae'' or ''A ...
, the country's second most popular sauce after
fish sauce Fish sauce is a liquid condiment made from fish or krill that have been coated in salt and fermented for up to two years. It is used as a staple seasoning in East Asian cuisine and Southeast Asian cuisine, particularly Myanmar, Cambodia, L ...
, has been chock full of cancer agents since at least 2001", reported the '' Thanh Nien'' daily. "Why didn't anyone tell us?" The carcinogen in Asian sauces is 3-MCPD and its metabolite 1,3-DCP, which has been an ongoing problem affecting multiple continents. Vietnamese vegetables and fruits were also found to have banned pesticides. * The 2005 Indonesia food scare, where carcinogenic formaldehyde was found to be added as a preservative to noodles,
tofu or bean curd is a food prepared by Coagulation (milk), coagulating soy milk and then pressing the resulting curds into solid white blocks of varying softness: ''silken'', ''soft'', ''firm'', and ''extra (or super) firm''. It originated in Chin ...
, salted fish, and meatballs. * In 2008 Chinese milk scandal, melamine was discovered to have been added to milk and infant formula which caused 54,000 babies to be sent to the hospital. Six babies died because of kidney stones related to the contaminant.


Hair in food

There is a heavy stigma attached to the presence of hair in food in most societies. There is a risk that it may induce choking and
vomiting Vomiting (also known as emesis, puking and throwing up) is the forceful expulsion of the contents of one's stomach through the mouth and sometimes the nose. Vomiting can be the result of ailments like food poisoning, gastroenteritis, pre ...
, and also that it may be contaminated by toxic substances. Views differ as to the level of risk it poses to the inadvertent consumer. In most countries, people working in the food industry are required to cover their hair because it will contaminate the food. When people are served food which contains hair in restaurants or cafés, it is usual for them to complain to the staff. There are a range of possible reasons for the objection to hair in food, ranging from cultural taboos to the simple fact that it is difficult to digest and unpleasant to eat. It may also be interpreted as a sign of more widespread problems with hygiene. The introduction of complete-capture hairnets is believed to have resulted in a decrease in incidents of contamination of this type. Sometimes protein from human hair is used as a food ingredient, in bread and other such similar products. Such use of human hair in food is forbidden in
Islam Islam is an Abrahamic religions, Abrahamic monotheistic religion based on the Quran, and the teachings of Muhammad. Adherents of Islam are called Muslims, who are estimated to number Islam by country, 2 billion worldwide and are the world ...
. Historically, in
Judaism Judaism () is an Abrahamic religions, Abrahamic, Monotheism, monotheistic, ethnic religion that comprises the collective spiritual, cultural, and legal traditions of the Jews, Jewish people. Religious Jews regard Judaism as their means of o ...
, finding hair in food was a sign of bad luck.


Processing contaminants

Processing contaminants are generated during the processing of foods (e.g., heating,
fermentation Fermentation is a type of anaerobic metabolism which harnesses the redox potential of the reactants to make adenosine triphosphate (ATP) and organic end products. Organic molecules, such as glucose or other sugars, are catabolized and reduce ...
). They are absent in the raw materials, and are formed by chemical reactions between natural and/or added food constituents during processing. The presence of these contaminants in processed foods cannot be entirely avoided. Technological processes can be adjusted and/or optimized, however, in order to reduce the levels of formation of processing contaminants. Examples are: nitrosamines, polycyclic aromatic hydrocarbons (PAH), heterocyclic amines,
histamine Histamine is an organic nitrogenous compound involved in local immune responses communication, as well as regulating physiological functions in the gut and acting as a neurotransmitter for the brain, spinal cord, and uterus. Discovered in 19 ...
, acrylamide, furan,
benzene Benzene is an Organic compound, organic chemical compound with the Chemical formula#Molecular formula, molecular formula C6H6. The benzene molecule is composed of six carbon atoms joined in a planar hexagonal Ring (chemistry), ring with one hyd ...
, trans fat, 3-MCPD, semicarbazide, 4-hydroxynonenal (4-HNE), and ethyl carbamate. There is also the possibility of metal chips from the processing equipment contaminating food. These can be identified using metal detection equipment. In many conveyor lines, the line will be stopped, or when weighing the product with a Check weigher, the item can be rejected for being over- or underweight or because small pieces of metal are detected within it.


Emerging food contaminants

While many food contaminants have been known for decades, the formation and presence of certain chemicals in foods has been discovered relatively recently. These are the so-called emerging food contaminants like acrylamide, furan,
benzene Benzene is an Organic compound, organic chemical compound with the Chemical formula#Molecular formula, molecular formula C6H6. The benzene molecule is composed of six carbon atoms joined in a planar hexagonal Ring (chemistry), ring with one hyd ...
, perchlorate, perfluorooctanoic acid ( PFOA), 3-monochloropropane-1,3-diol (3-MCPD), 4-hydroxynonenal, and (4-HNE). Microplastics are often found in bottled water.
Polypropylene Polypropylene (PP), also known as polypropene, is a thermoplastic polymer used in a wide variety of applications. It is produced via chain-growth polymerization from the monomer Propene, propylene. Polypropylene belongs to the group of polyolefin ...
infant feeding bottles cause microplastics exposure to infants.


Safety and regulation

Acceptable daily intake (ADI) levels and tolerable concentrations of contaminants in individual foods are determined on the basis of the "No Observed Adverse Effect Level" (NOAEL) in animal experiments, by using a safety factor (usually 100). The maximum concentrations of contaminants allowed by legislation are often well below toxicological tolerance levels, because such levels can often be reasonably achieved by using good agricultural and manufacturing practices. Regulatory officials, in order to combat the dangers associated with foodborne viruses, are pursuing various possible measures. * The EFSA published a report in 2011 on "scientific opinion regarding an update of the present knowledge on the occurrence and control of foodborne viruses". * This year, an expert working group created by the European Committee for Standardization (CEN), is expected to publish a standard method for the detection of norovirus and hepatitis A virus in food. * The CODEX Committee on Food Hygiene (CCFH) is also working on a guideline which is now ready for final adoption. *
European Commission The European Commission (EC) is the primary Executive (government), executive arm of the European Union (EU). It operates as a cabinet government, with a number of European Commissioner, members of the Commission (directorial system, informall ...
Regulation (EC) No 2073/2005 of 15 November 2005 indicates that "foodstuffs should not contain micro-organisms or their toxins or metabolites in quantities that present an unacceptable risk for human health", underlining that methods are required for foodborne virus detection.


Food contaminant testing

To maintain the high quality of food and comply with health, safety, and environmental regulatory standards, it is best to rely on food contaminant testing through an independent third party, such as laboratories or certification companies. For manufacturers, the testing for food contaminants can minimize the risk of noncompliance in relation to raw ingredients, semi-manufactured foods, and final products. Also, food contaminant testing assures consumers
safety Safety is the state of being protected from harm or other danger. Safety can also refer to the control of recognized hazards in order to achieve an acceptable level of risk. Meanings The word 'safety' entered the English language in the 1 ...
and quality of purchased food products and can prevent foodborne diseases, and chemical, microbiological, or physical food hazards. The establishment of ADIs for certain emerging food contaminants is currently an active area of research and regulatory debate.


Food contaminant detection method

The conventional food contaminant test methods may be limited by complicated/tedious sample preparing procedure, long testing time, sumptuous instrument, and professional operator. However, some rapid, novel, sensitive, and easy to use and affordable methods were developed including: * Cyanidin quantification by naphthalimide-based azo dye colorimetric probe * Lead quantification by modified immunoassay test strip based on a heterogeneously sized gold amplified probe * Microbial toxin by HPLC with UV-Vis or fluorescence detection and competitive immunoassays with ELISA configuration * Bacterial virulence genes detection reverse-transcription polymerase chain reaction (RT-PCR) and DNA colony hybridization * Pesticide detection and quantification by strip-based immunoassay, a test strip based on functionalized AuNPs, and test strip, surface-enhanced raman spectroscopy (SERS) * Enrofloxacin (chickens antibiotic) quantification by a Ru(phen)3 2+- doped silica fluorescent
nanoparticle A nanoparticle or ultrafine particle is a particle of matter 1 to 100 nanometres (nm) in diameter. The term is sometimes used for larger particles, up to 500 nm, or fibers and tubes that are less than 100 nm in only two directions. At ...
(NP) based immunochromatographic test strip and a portable fluorescent strip reader * Nitrite quantification by The PRhB-based electrochemical sensors and Ion selective electrodes (ISEs)


See also

* '' Bad Bug Book'' from the U.S.
Food and Drug Administration The United States Food and Drug Administration (FDA or US FDA) is a List of United States federal agencies, federal agency of the United States Department of Health and Human Services, Department of Health and Human Services. The FDA is respo ...
* '' The Joint FAO/WHO Expert Committee Report on Food Additives'' * List of food contamination incidents


References


External links


Office of Food Additive Safety
at the US Food and Drug Administration's website
Chemical Risks in Food
from the
World Health Organization The World Health Organization (WHO) is a list of specialized agencies of the United Nations, specialized agency of the United Nations which coordinates responses to international public health issues and emergencies. It is headquartered in Gen ...

Briefing on GM Food Contamination


from the US Food and Drug Administration's website {{Authority control Food safety * Nutrition