Fluoroestradiol F-18, also known as
sup>18F6α-fluoroestradiol and sold under the brand name Cerianna, is a
radioactive diagnostic agent indicated for use with
positron emission tomography
Positron emission tomography (PET) is a functional imaging technique that uses radioactive substances known as radiotracers to visualize and measure changes in metabolic processes, and in other physiological activities including blood flow, r ...
(PET)
imaging
Imaging is the representation or reproduction of an object's form; especially a visual representation (i.e., the formation of an image).
Imaging technology is the application of materials and methods to create, preserve, or duplicate images.
...
.
It is an
analog
Analog or analogue may refer to:
Computing and electronics
* Analog signal, in which information is encoded in a continuous variable
** Analog device, an apparatus that operates on analog signals
*** Analog electronics, circuits which use analog ...
of
estrogen
Estrogen (also spelled oestrogen in British English; see spelling differences) is a category of sex hormone responsible for the development and regulation of the female reproductive system and secondary sex characteristics. There are three ...
and is used to detect
estrogen receptor
Estrogen receptors (ERs) are proteins found in cell (biology), cells that function as receptor (biochemistry), receptors for the hormone estrogen (17β-estradiol). There are two main classes of ERs. The first includes the intracellular estrogen ...
-positive
breast cancer
Breast cancer is a cancer that develops from breast tissue. Signs of breast cancer may include a Breast lump, lump in the breast, a change in breast shape, dimpling of the skin, Milk-rejection sign, milk rejection, fluid coming from the nipp ...
lesion
A lesion is any damage or abnormal change in the tissue of an organism, usually caused by injury or diseases. The term ''Lesion'' is derived from the Latin meaning "injury". Lesions may occur in both plants and animals.
Types
There is no de ...
s.
Chemistry
Chemically, fluoroestradiol F-18 is
sup>18F6α-fluoro-3,17β-diol-estratriene-1,3,5(10).
History
Fluoroestradiol F-18 was approved for medical use in the United States in May 2020.
References
External links
*
{{DEFAULTSORT:Fluoroestradiol F-18
Secondary alcohols
Estradiol
Estranes
Estrogens
Medicinal radiochemistry
PET radiotracers
Hydroxyarenes
Radiopharmaceuticals
Organofluorides
Breast cancer