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Flowering Locus C (''FLC'') is a MADS-box gene that in late-flowering ecotypes of the plant ''
Arabidopsis thaliana ''Arabidopsis thaliana'', the thale cress, mouse-ear cress or arabidopsis, is a small flowering plant native to Eurasia and Africa. ''A. thaliana'' is considered a weed; it is found along the shoulders of roads and in disturbed land. A winter a ...
'' is responsible for vernalization. In a new seedling ''FLC'' is expressed, which prevents flowering. Upon exposure to cold, less ''FLC'' is expressed (to a degree depending on the amount of cold), and flowering becomes possible. ''FLC'' is extensively regulated through epigenetic modifications and transcriptional control. The expression of ''FLC'' is affected by other genes including ''
FLK The Falkland Islands (; es, Islas Malvinas, link=no ) is an archipelago in the South Atlantic Ocean on the Patagonian Shelf. The principal islands are about east of South America's southern Patagonian coast and about from Cape Dubou ...
'', ''
FCA FCA may refer to: Arts * Federation of Canadian Artists * Foundation for Contemporary Art, in Ghana * Foundation for Contemporary Arts, in the United States Business and economics * False Claims Act, a United States federal law * Federal Cus ...
'' and '' VERNALIZATION2'' (''VRN2''). Wild ''Arabidopsis'' plants have different alleles for the ''FLC'' gene, which correspond to ecotypes which either (a) flower rapidly and produce a number of generations during one summer (''summer-annual''), or (b) flower only after vernalization (''winter-annual'' or ''late-flowering''). This kind of variation can also be provided by variation in the '' FRIGIDA'' (''FRI'') gene.


References

Arabidopsis thaliana genes Plant physiology {{botany-stub