The flocculonodular lobe ( vestibulocerebellum) is a lobe of the

cerebellum The cerebellum (Latin for "little brain") is a major feature of the hindbrain of all vertebrates. Although usually smaller than the cerebrum, in some animals such as the mormyrid fishes it may be as large as or even larger. In humans, the cere ...

consisting of the nodule and the

flocculus The flocculus (Latin: ''tuft of wool'', diminutive) is a small lobe of the cerebellum at the posterior border of the middle cerebellar peduncle anterior to the biventer lobule. Like other parts of the cerebellum, the flocculus is involved in moto ...

. The two flocculi are connected to the midline structure called the nodulus by thin pedicles. It is placed on the anteroinferior surface of cerebellum. This region of the cerebellum has important connections to the vestibular nuclei and uses information about head movement to influence eye movement. Lesions to this area can result in multiple deficits in visual tracking and oculomotor control (such as

nystagmus Nystagmus is a condition of involuntary (or voluntary, in some cases) eye movement. Infants can be born with it but more commonly acquire it in infancy or later in life. In many cases it may result in reduced or limited vision. Due to the invol ...

and

vertigo Vertigo is a condition where a person has the sensation of movement or of surrounding objects moving when they are not. Often it feels like a spinning or swaying movement. This may be associated with nausea, vomiting, sweating, or difficulties ...

), integration of vestibular information for eye and head control, as well as control of axial muscles for balance. This lobe is also involved in the maintenance of balance equilibrium and muscle tone. The most common cause of damage to the flocculonodular lobe is medulloblastoma in childhood.

References

External links

NIF Search - Flocculonodular lobe
via the

Neuroscience Information Framework The Neuroscience Information Framework is a repository of global neuroscience web resources, including experimental, clinical, and translational neuroscience databases, knowledge bases, atlases, and genetic/ genomic resources and provides many aut ...

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