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' () is a
Latin Latin ( or ) is a classical language belonging to the Italic languages, Italic branch of the Indo-European languages. Latin was originally spoken by the Latins (Italic tribe), Latins in Latium (now known as Lazio), the lower Tiber area aroun ...
phrase that means "first, do no harm". The phrase is sometimes recorded as '. Non-maleficence, which is derived from the maxim, is one of the principal precepts of
bioethics Bioethics is both a field of study and professional practice, interested in ethical issues related to health (primarily focused on the human, but also increasingly includes animal ethics), including those emerging from advances in biology, me ...
that all students in healthcare are taught in school and is a fundamental principle throughout the world. Another way to state it is that, "given an existing problem, it may be better not to do something, or even to do nothing, than to risk causing more harm than good." It reminds healthcare personnel to consider the possible harm that any intervention might do. It is invoked when debating the use of an intervention that carries an obvious risk of harm but a less certain chance of benefit. Non-maleficence is often contrasted with its complement, beneficence. Young and Wagner argued that, for healthcare professionals and other professionals subject to a moral code, in general beneficence takes priority over non-maleficence (“first, do good,” not “first, do no harm”) both historically and philosophically. Indeed, beneficence is the Hippocratic priority both in the Oath and in ''Epidemics I'', which "First do no harm" and "Primum non nocere" reverse quite contrarily to Hippocratic and other classical authorities.


Origin

The origin of the phrase is uncertain. Some early versions of the Hippocratic Oath include the promise "to abstain from doing harm" () but do not include the precise phrase. Perhaps the closest approximation in the
Hippocratic Corpus The Hippocratic Corpus (Latin: ''Corpus Hippocraticum''), or Hippocratic Collection, is a collection of around 60 early Ancient Greek medical works strongly associated with the physician Hippocrates and his teachings. The Hippocratic Corpus cov ...
is in ''Epidemics'': "The physician must ... have two special objects in view with regard to disease, namely, to do good or to do no harm" (book I, sect. 11, trans. Adams, ). According to Gonzalo Herranz, Professor of Medical Ethics at the
University of Navarra The University of Navarra is a private Catholic research university located on the southeast border of Pamplona, Navarre, Spain. It was founded in 1952 by Saint Josemaría Escrivá de Balaguer, the founder of '' Opus Dei'', as a corporat ...
, ''Primum non nocere'' was introduced into American and
British British may refer to: Peoples, culture, and language * British people, nationals or natives of the United Kingdom, British Overseas Territories and Crown Dependencies. * British national identity, the characteristics of British people and culture ...
medical culture by Worthington Hooker in his 1847 book ''Physician and Patient''. Hooker attributed it to the
Paris Paris () is the Capital city, capital and List of communes in France with over 20,000 inhabitants, largest city of France. With an estimated population of 2,048,472 residents in January 2025 in an area of more than , Paris is the List of ci ...
ian pathologist and clinician Auguste François Chomel (1788–1858), the successor of Laennec in the chair of medical pathology, and the preceptor of Pierre Louis. Apparently, the axiom was part of Chomel's oral teaching. Hooker, however, was quoting an earlier work by Elisha Bartlett who, on pages 288–289, says "The golden axiom of Chomel, that it is only the second law of therapeutics to do good, its first law being this – not to do harm – is gradually finding its way into the medical mind, preventing an incalculable amount of positive ill." However, Hooker used neither the specific expression, nor the traditional Latin phrase. A detailed investigation of the origins of the
aphorism An aphorism (from Greek ἀφορισμός: ''aphorismos'', denoting 'delimitation', 'distinction', and 'definition') is a concise, terse, laconic, or memorable expression of a general truth or principle. Aphorisms are often handed down by tra ...
was reported by the clinical pharmacologist Cedric M. Smith in the April 2005 issue of ''
The Journal of Clinical Pharmacology ''The Journal of Clinical Pharmacology'' is a peer-reviewed medical journal that covers the field of pharmacology. The editor-in-chief is Joseph S. Bertino, Jr. ( Bertino Consulting). It was established in 1961 and is currently published by John Wi ...
''. It addresses the questions of the origin and chronology of appearance of the maxim. Rather than being of ancient origin as usually assumed, the specific expression, and its even more distinctive associated Latin phrase, has been traced back to an attribution to
Thomas Sydenham Thomas Sydenham (; 10 September 1624 – 29 December 1689) was an England, English physician. He was the author of ''Observationes Medicae'' (1676) which became a standard textbook of medicine for two centuries so that he became known as 'The ...
(1624–1689) in a book by
Thomas Inman Thomas Inman (27 January 1820 – 3 May 1876) was a house-surgeon to the Liverpool Royal Infirmary. In his lifetime he had numerous medical papers published. He was also an amateur mythologist, and wrote ''Ancient Pagan and Modern Christian Sym ...
(1860), ''Foundation for a New Theory and Practice of Medicine''. Inman's book and his attribution were reviewed by an author who signed simply as "H. H." in ''
The American Journal of the Medical Sciences ''The American Journal of the Medical Sciences'' is a monthly peer-reviewed medical journal. History The journal was established in 1820 as the ''Philadelphia Journal of the Medical and Physical Sciences'' by Nathaniel Chapman. A new series wa ...
'', also in 1860. Smith's article also reviews the various uses of the now popular aphorism, its limitations as a moral injunction, and its increasingly frequent use in a variety of contexts. The origin stories are probably apocryphal, and the true origins in either language, or any language, misty and proverbial. An American surgeon, L.A. Stimson, used the expression in 1879 and again in 1906 (in the same journal). That it was in common use by the 20th century is apparent from later mentions, such as by the prominent
obstetrician Obstetrics is the field of study concentrated on pregnancy, childbirth and the postpartum period. As a medical specialty, obstetrics is combined with gynecology under the discipline known as obstetrics and gynecology (OB/GYN), which is a surgi ...
J. Whitridge Williams in 1911, as well as detailed discussion of its use in a popular book authored by Dr. Morris Fishbein, editor of ''
The Journal of the American Medical Association ''JAMA'' (''The Journal of the American Medical Association'') is a peer-reviewed medical journal published 48 times a year by the American Medical Association. It publishes original research, reviews, and editorials covering all aspects of bi ...
'' in 1930.


See also

*
Ahimsa (, IAST: , ) is the ancient Indian principle of nonviolence which applies to actions towards all living beings. It is a key virtue in Indian religions like Jainism, Buddhism and Hinduism. (also spelled Ahinsa) is one of the cardinal vi ...
*
Ethics Ethics is the philosophy, philosophical study of Morality, moral phenomena. Also called moral philosophy, it investigates Normativity, normative questions about what people ought to do or which behavior is morally right. Its main branches inclu ...
*
Harm principle The harm principle holds that the actions of individuals should be limited only to prevent harm to other individuals. John Stuart Mill articulated the principle in the 1859 essay '' On Liberty'', where he argued that "The only purpose for which ...
* Leaving the world a better place *
Meta-ethics In metaphilosophy and ethics, metaethics is the study of the nature, scope, ground, and meaning of moral judgment, ethical belief, or values. It is one of the three branches of ethics generally studied by philosophers, the others being normativ ...
* Non-aggression principle *
Non-violence Nonviolence is the personal practice of not causing harm to others under any condition. It may come from the belief that hurting people, animals and/or the environment is unnecessary to achieve an outcome and it may refer to a general philosoph ...
*
Nursing ethics Nursing ethics is a branch of applied ethics that concerns itself with activities in the field of nursing. Nursing ethics shares many principles with medical ethics, such as beneficence, non-maleficence, and respect for autonomy. It can be distin ...
* Principlism


References


External links


Article presenting various views on the principle of "Do no harm"
{{Medical harm Ethical principles Medical ethics Latin medical words and phrases History of ancient medicine Nursing ethics