Fibroma of tendon sheath is a

benign tumor A benign tumor is a mass of Cell (biology), cells (tumor) that does not Cancer invasion, invade neighboring tissue or Metastasis, metastasize (spread throughout the body). Compared to Cancer, malignant (cancerous) tumors, benign tumors generally ...

that presents as a small subcutaneous nodule that slowly increases in size. This is a notably uncommon condition. According to

case report In medicine, a case report is a detailed report of the symptoms, signs, diagnosis, treatment, and follow-up of an individual patient. Case reports may contain a demographic profile of the patient, but usually describe an unusual or novel occurrenc ...

literature, the tumors often have a multinodular growth pattern, with individual nodules being composed of bland, slender, spindle-shaped cells (myofibroblasts) in a dense, fibrous matrix.” A common microscopic finding is the presence of elongated, slit-like blood vessels. The lesions nearly always arise in the

distal Standard anatomical terms of location are used to describe unambiguously the anatomy of humans and other animals. The terms, typically derived from Latin or Greek roots, describe something in its standard anatomical position. This position provi ...

portions of the extremities. They often occur on the fingers, hands, toes, or feet. Although they are benign, they may recur after surgical excision in up to 40% of people. Although they may be regarded as a tumor of the skin, the lesions arise from tendons and

aponeuroses An aponeurosis (; : aponeuroses) is a flattened tendon by which muscle attaches to bone or fascia. Aponeuroses exhibit an ordered arrangement of collagen fibres, thus attaining high tensile strength in a particular direction while being vulnerable ...

in superficial sites, and are therefore properly classified in the category of soft-tissue tumor. The

World Health Organization The World Health Organization (WHO) is a list of specialized agencies of the United Nations, specialized agency of the United Nations which coordinates responses to international public health issues and emergencies. It is headquartered in Gen ...

in 2020 reclassified these tumors as a specific, benign tumor type in a broad category of soft tissue

neoplasms A neoplasm () is a type of abnormal and excessive growth of tissue (biology), tissue. The process that occurs to form or produce a neoplasm is called neoplasia. The growth of a neoplasm is uncoordinated with that of the normal surrounding tiss ...

termed

fibroblastic and myofibroblastic tumors Fibroblastic and myofibroblastic tumors (FMTs) are tumors which develop from the mesenchymal stem cells which differentiate into fibroblasts (the most common cell type in connective tissue) and/or the myocytes/ myoblasts that differentiate into ...

. The biological nature of fibroma of tendon sheath is not known, but the category appears to comprise a number of different pathological processes. It is considered that about one-third of the lesions in this category may be acral variants of the entity

nodular fasciitis Nodular fasciitis (NF) is a benign, soft tissue tumor composed of myofibroblasts that typically occurs in subcutaneous tissue, fascia, and/or muscles. The literature sometimes titles rare NF variants according to their tissue locations. The most f ...

References

Dermal and subcutaneous growths Connective and soft tissue neoplasms {{Soft tissue tumors and sarcomas

See also

References