Ferroxidase also known as Fe(II):oxygen oxidoreductase is an
enzyme
An enzyme () is a protein that acts as a biological catalyst by accelerating chemical reactions. The molecules upon which enzymes may act are called substrate (chemistry), substrates, and the enzyme converts the substrates into different mol ...
that catalyzes the
oxidization of
iron II to
iron III:
: 4 Fe
2+ + 4 H
+ + O
2 ⇔ 4 Fe
3+ + 2H
2O
Examples
Human genes encoding proteins with ferroxidase activity include:
*
CP – Ceruloplasmin
*
FTH1
Ferritin heavy chain is a ferroxidase enzyme that in humans is encoded by the ''FTH1'' gene. FTH1 gene is located on chromosome 11, and its mutation causes Hemochromatosis type 5.
Function
This gene encodes the heavy subunit of ferritin, th ...
– Ferritin heavy chain
*
FTMT – Ferritin, mitochondrial
*
HEPH - Hephaestin
References
*
*
*
EC 1.16.3
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