Fenpiverinium is an

anticholinergic Anticholinergics (anticholinergic agents) are substances that block the action of the neurotransmitter called acetylcholine (ACh) at synapses in the central and peripheral nervous system. These agents inhibit the parasympathetic nervous syste ...

and

antispasmodic An antispasmodic (synonym: spasmolytic) is a pharmaceutical drug or other agent that suppresses muscle spasms. Smooth muscle spasm One type of antispasmodics is used for smooth muscle relaxation, especially in tubular organs of the gastrointestin ...

compound; it is marketed as a

combination drug A combination drug or a fixed-dose combination (FDC) is a medicine that includes two or more active ingredients combined in a single dosage form. Terms like "combination drug" or "combination drug product" can be common shorthand for a FDC pr ...

with

pitofenone Pitofenone is an antispasmodic. Pitofenone is typically used in combination with fenpiverinium bromide, and metamizole sodium. Previously produced as Baralgin by Sanofi Aventis, the drug is currently sold in Eastern Europe under various trad ...

hydrochloride and either

nimesulide Nimesulide is a nonsteroidal anti-inflammatory drug (NSAID) with pain medication and fever reducing properties. Its approved indications are the treatment of acute pain, the symptomatic treatment of osteoarthritis, and primary dysmenorrhoea in ...

or metamizole in Eastern Europe and India to treat smooth muscle spasms and pain. The combination with metamizole was removed from the market in Lithuania for safety reasons in 2000 and a boxed warning against use by children and adolescents was added in Serbia in 2005. In 2016 India banned marketing of the combination with nimesulide along with 344 other combination drugs; the order was overturned in December and appealed by the Government in January 2017.

References

Muscarinic antagonists Quaternary ammonium compounds Piperidines Butyramides {{gastrointestinal-drug-stub