Fannie Eleanor Williams
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Fannie Eleanor Williams MBE,
ARRC ARRC may stand for: * Advanced Radar Research Center, University of Oklahoma, Oklahoma, USA * Advanced Institute for Research on Religion and Culture, Hyderabad, India * Advanced Rocket Research Center, NCTU, Taiwan * Allied Rapid Reaction Corps, ...
(4 July 1884 – 16 June 1963), known as Eleanor Williams, was an Australian scientist. She served as a
bacteriologist A bacteriologist is a microbiologist, or similarly trained professional, in bacteriology— a subdivision of microbiology that studies bacteria, typically Pathogenic bacteria, pathogenic ones. Bacteriologists are interested in studying and learnin ...
during
World War I World War I or the First World War (28 July 1914 – 11 November 1918), also known as the Great War, was a World war, global conflict between two coalitions: the Allies of World War I, Allies (or Entente) and the Central Powers. Fighting to ...
, and was the third scientist and the first woman appointed to work at the
Walter and Eliza Hall Institute of Medical Research Walter may refer to: People and fictional characters * Walter (name), including a list of people and fictional and mythical characters with the given name or surname * Little Walter, American blues harmonica player Marion Walter Jacobs (1930–1 ...
after its establishment in 1915. She directed a laboratory studying infectious diseases, and had particular expertise in
dysentery Dysentery ( , ), historically known as the bloody flux, is a type of gastroenteritis that results in bloody diarrhea. Other symptoms may include fever, abdominal pain, and a feeling of incomplete defecation. Complications may include dehyd ...
,
hydatid disease Hydatid may refer to: * Echinococcosis * ''Echinococcus granulosus'', known as the hydatid tapeworm * Hydatid of Morgagni The hydatid of Morgagni can refer to one of two closely related bodily structures: * Appendix of testis (in the male) * Para ...
and
snake venom Snake venom is a highly toxic saliva containing zootoxins that facilitates in the immobilization and digestion of prey. This also provides defense against threats. Snake venom is usually injected by unique fangs during a Snakebite, bite, though ...
. She co-founded Australia's first
blood bank A blood bank is a center where blood gathered as a result of blood donation is stored and preserved for later use in blood transfusion. The term "blood bank" typically refers to a department of a hospital usually within a clinical pathology labora ...
.


Early life and education

Fannie Eleanor Williams was born in
Adelaide Adelaide ( , ; ) is the list of Australian capital cities, capital and most populous city of South Australia, as well as the list of cities in Australia by population, fifth-most populous city in Australia. The name "Adelaide" may refer to ei ...
,
South Australia South Australia (commonly abbreviated as SA) is a States and territories of Australia, state in the southern central part of Australia. With a total land area of , it is the fourth-largest of Australia's states and territories by area, which in ...
on 4 July 1884. She was the second child and eldest daughter of James Williams and his wife Helen DuBois. Williams grew up in
The Reedbeds The Reedbeds was in the 19th and early 20th centuries the generally recognised name for an area of seasonal freshwater wetlands to the west of Adelaide, South Australia comprising the floodplains of the River Torrens, and drained to Gulf St Vinc ...
, near
Henley Beach Henley Beach is a coastal suburb of Adelaide, South Australia in the City of Charles Sturt. History Henley Beach draws its name from Henley-on-Thames, England. The land where it stands, sections 448 and 2080 in the Hundred of Yatala, was ini ...
, where her father was a farmer. Williams trained as a nurse at the
Adelaide Children's Hospital The Women's and Children's Hospital (WCH) is a hospital dedicated to the care of women and children in Adelaide, South Australia. It was established in March 1989, when the Queen Victoria Hospital and Adelaide Children's Hospital were amalgamate ...
between 1904 and 1907. She was appointed sister in charge of the Thomas Elder Laboratory in 1907, and worked there for two years as an assistant to pathologist Dr. Thomas Borthwick. In December 1909, Williams took up a position as nurse inspector with the
Unley Unley is an inner-southern suburb of Adelaide, South Australia, within the City of Unley. The suburb is the home of the Sturt Football Club in the South Australian National Football League (SANFL). Unley neighbours Adelaide Park Lands, Fullar ...
Local Board of Health for which she undertook home visits and tested patients for
diphtheria Diphtheria is an infection caused by the bacteria, bacterium ''Corynebacterium diphtheriae''. Most infections are asymptomatic or have a mild Course (medicine), clinical course, but in some outbreaks, the mortality rate approaches 10%. Signs a ...
,
measles Measles (probably from Middle Dutch or Middle High German ''masel(e)'', meaning "blemish, blood blister") is a highly contagious, Vaccine-preventable diseases, vaccine-preventable infectious disease caused by Measles morbillivirus, measles v ...
, and other
notifiable disease A notifiable disease is any disease that is required by law to be reported to government authorities. The collation of information allows the authorities to monitor the disease, and provides early warning of possible outbreaks. In the case of lives ...
s. In 1911, Williams returned to work with Dr. Borthwick as an attendant in a new pathology research laboratory at the Adelaide Hospital. She was the first woman in South Australia to hold such an appointment. She remained in this role until late 1914.


Wartime service

After the outbreak of World War I in 1914, Eleanor Williams was invited by Dr Trent Champion de Crespigny to join him on active service with the
First Australian Imperial Force The First Australian Imperial Force (1st AIF) was the main Expeditionary warfare, expeditionary force of the Australian Army during the First World War. It was formed as the Australian Imperial Force (AIF) following United Kingdom of Great Bri ...
. Infectious disease was emerging as a significant issue for the campaign in Turkey and the Middle East, and the army wanted to recruit people with bacteriological and laboratory training to work on the problem. Accordingly, Williams enlisted with the
Australian Army Nursing Service The Australian Army Nursing Service (AANS) was an Australian Army Reserve unit which provided a pool of trained civilian nurses who had volunteered for military service during wartime. The AANS was formed in 1902 by amalgamating the nursing servic ...
on 20 July 1915 and embarked for Egypt a fortnight later on the '' RMS Orontes''. On arrival, Williams was posted to the 3rd Australian General Hospital on the island of
Lemnos Lemnos ( ) or Limnos ( ) is a Greek island in the northern Aegean Sea. Administratively the island forms a separate municipality within the Lemnos (regional unit), Lemnos regional unit, which is part of the North Aegean modern regions of Greece ...
in Greece. This was one of the hospitals that received patients from the Gallipoli Campaign. Williams' record at the
Australian War Memorial The Australian War Memorial (AWM) is a national war memorial, war museum, museum and archive dedicated to all Australians who died as a result of war, including peacekeeping duties. The AWM is located in Campbell, Australian Capital Territory, C ...
states that she enlisted with the rank of Staff Nurse on 20 July 1915, and rose to the rank of Temporary Sister. She served in Egypt, Lemnos, England and France, was mentioned twice in despatches, and was awarded the
Royal Red Cross The Royal Red Cross (RRC) is a military decoration awarded in the United Kingdom and Commonwealth for exceptional services in military nursing. It was created in 1883, and the first two awards were to Florence Nightingale and Jane Cecilia Deeb ...
(2nd Class). Although Williams enlisted as a nurse, she worked exclusively in the laboratory as a bacteriologist, the only Australian woman to serve in such a capacity. Working alongside Dr Charles James Martin, Director of the
Lister Institute The Lister Institute of Preventive Medicine, informally known as the Lister Institute, was established as a research institute (the British Institute of Preventive Medicine) in 1891, with bacteriologist Marc Armand Ruffer as its first director, ...
, she performed ground-breaking work on
dysentery Dysentery ( , ), historically known as the bloody flux, is a type of gastroenteritis that results in bloody diarrhea. Other symptoms may include fever, abdominal pain, and a feeling of incomplete defecation. Complications may include dehyd ...
, and quickly became known as an expert in this field. She continued to work with Martin throughout the war, on a variety of infectious diseases, including
meningitis Meningitis is acute or chronic inflammation of the protective membranes covering the brain and spinal cord, collectively called the meninges. The most common symptoms are fever, intense headache, vomiting and neck stiffness and occasion ...
,
streptococci ''Streptococcus'' is a genus of gram-positive spherical bacteria that belongs to the family Streptococcaceae, within the order Lactobacillales (lactic acid bacteria), in the phylum Bacillota. Cell division in streptococci occurs along a sing ...
,
staphylococci ''Staphylococcus'', from Ancient Greek σταφυλή (''staphulḗ''), meaning "bunch of grapes", and (''kókkos''), meaning "kernel" or " Kermes", is a genus of Gram-positive bacteria in the family Staphylococcaceae from the order Bacillale ...
,
gas gangrene Gas gangrene (also known as clostridial myonecrosis) is a bacterial infection that produces tissue gas in gangrene. This deadly form of gangrene usually is caused by '' Clostridium perfringens'' bacteria. About 1,000 cases of gas gangrene are r ...
, and epidemic
influenza Influenza, commonly known as the flu, is an infectious disease caused by influenza viruses. Symptoms range from mild to severe and often include fever, runny nose, sore throat, muscle pain, headache, coughing, and fatigue. These sympto ...
.


Scientific career

Following her repatriation in 1919, Eleanor Williams moved to
Melbourne Melbourne ( , ; Boonwurrung language, Boonwurrung/ or ) is the List of Australian capital cities, capital and List of cities in Australia by population, most populous city of the States and territories of Australia, Australian state of Victori ...
, and was appointed to the position of 'second assistant' at the newly-established
Walter and Eliza Hall Institute of Medical Research Walter may refer to: People and fictional characters * Walter (name), including a list of people and fictional and mythical characters with the given name or surname * Little Walter, American blues harmonica player Marion Walter Jacobs (1930–1 ...
by director
Sydney Patterson Sydney Wentworth Patterson MB BS, MD, DSc, FRCP (born 1882 in Melbourne, Australia, died 1960 in London, England) was a physician, medical researcher and first director of the Walter and Eliza Hall Institute of Medical Research in Melbourne, A ...
. Williams had worked with Patterson on influenza during the war. She was the third staff member appointed to the Institute, and the first woman. She was also the only researcher with no medical or university qualification. In the early 1920s, the Institute's focus was on respiratory and intestinal infections, and Williams worked on
pneumonia Pneumonia is an Inflammation, inflammatory condition of the lung primarily affecting the small air sacs known as Pulmonary alveolus, alveoli. Symptoms typically include some combination of Cough#Classification, productive or dry cough, ches ...
,
syphilis Syphilis () is a sexually transmitted infection caused by the bacterium ''Treponema pallidum'' subspecies ''pallidum''. The signs and symptoms depend on the stage it presents: primary, secondary, latent syphilis, latent or tertiary. The prim ...
and
dysentery Dysentery ( , ), historically known as the bloody flux, is a type of gastroenteritis that results in bloody diarrhea. Other symptoms may include fever, abdominal pain, and a feeling of incomplete defecation. Complications may include dehyd ...
, as well as the serological diagnosis of hydatid tapeworms. From 1923, she worked with
Charles Kellaway Charles Halliley Kellaway, (16 January 1889 – 13 December 1952) was an Australian medical researcher and science administrator. Biography Early years and education Charles Kellaway was born at the parsonage attached to St James's Old Cathe ...
on snake venom
serology Serology is the scientific study of Serum (blood), serum and other body fluids. In practice, the term usually refers to the medical diagnosis, diagnostic identification of Antibody, antibodies in the serum. Such antibodies are typically formed in r ...
, and later worked on
tuberculosis Tuberculosis (TB), also known colloquially as the "white death", or historically as consumption, is a contagious disease usually caused by ''Mycobacterium tuberculosis'' (MTB) bacteria. Tuberculosis generally affects the lungs, but it can al ...
. Williams occupied a position somewhere between that of research scientist, senior technician and general manager. While her lack of academic qualifications prevented her from lecturing at the
University of Melbourne The University of Melbourne (colloquially known as Melbourne University) is a public university, public research university located in Melbourne, Australia. Founded in 1853, it is Australia's second oldest university and the oldest in the state ...
, she established and led the Institute's Diagnostic Microbiology Laboratory, and attended international and national conferences where she presented papers in her own right. As the Institute grew in the late 1930s, Williams took on the responsibility for training and managing the Institute's research technicians. The training she provided was extremely thorough, and covered elements as diverse as animal care, the preparation of media and broths for bacterial culture, and glassblowing. She also trained junior scientists in practical bacteriology techniques. Among her trainees was
Frank Macfarlane Burnet Sir Frank Macfarlane Burnet (3 September 1899 – 31 August 1985), usually known as Macfarlane or Mac Burnet, was an Australian virology, virologist known for his contributions to immunology. He won a Nobel Prize in Physiology or Medicine, Nobe ...
, who later described her as "the centre of commonsense and helpfulness around which all the activities of the Institute rotated". During
World War II World War II or the Second World War (1 September 1939 – 2 September 1945) was a World war, global conflict between two coalitions: the Allies of World War II, Allies and the Axis powers. World War II by country, Nearly all of the wo ...
, Williams coordinated the Institute's war efforts, providing administrative and practical support to the Emergency Blood Transfusion Service, as well as working in the laboratory. She retired in 1957, and received an MBE for her work in the same year.


Red Cross Blood Transfusion Service

Eleanor Williams was closely involved with The Red Cross Blood Transfusion Service (now the
Australian Red Cross Blood Service Lifeblood, formally Australian Red Cross Lifeblood, is the national blood, milk, and microbiota donation and manufacturing service for Australia and is a branch of the Australian Red Cross. Lifeblood employs around 3,700 people across scienti ...
) from its inception in 1929 by the Victorian Division of the
Australian Red Cross Society Australian Red Cross, formally Australian Red Cross Society, is a humanitarian aid and community services charity in Australia. Tracing its history back to 1914 and being incorporated by royal charter in 1941, Australian Red Cross Society is ...
. In the first decade of the service, laboratory tests were carried out at the
Walter and Eliza Hall Institute of Medical Research Walter may refer to: People and fictional characters * Walter (name), including a list of people and fictional and mythical characters with the given name or surname * Little Walter, American blues harmonica player Marion Walter Jacobs (1930–1 ...
, under the supervision of Williams and her colleague Dr Ian Wood. The ability to deliver blood transfusions was limited by the lack of a
blood bank A blood bank is a center where blood gathered as a result of blood donation is stored and preserved for later use in blood transfusion. The term "blood bank" typically refers to a department of a hospital usually within a clinical pathology labora ...
, which would allow donated blood to be stored for future needs. In 1938, with World War II approaching, the decision was made to establish a blood bank at the
Royal Melbourne Hospital The Royal Melbourne Hospital (RMH), located in Parkville, Victoria, an inner suburb of Melbourne, is one of Australia's leading public hospitals. It is a major teaching hospital for tertiary health care with a reputation in clinical research. Th ...
, and Williams and Wood turned their attention to developing new techniques for storing blood and plasma, as well as to the logistical aspects of obtaining and administering the blood. The new Emergency Blood Transfusion Service was founded in May 1939 by Williams and Wood, with Williams managing the technical and administrative aspects of the service and Wood ensuring the supply of blood and serum in the field. Once war was declared, Williams' team immediately began testing and recording the blood groups of all soldiers prior to embarkation, so that
blood transfusion Blood transfusion is the process of transferring blood products into a person's Circulatory system, circulation intravenously. Transfusions are used for various medical conditions to replace lost components of the blood. Early transfusions used ...
s could more efficiently be performed in the field. In the first year of the war alone, her team, working as volunteers and in addition to their daily laboratory work, performed
blood typing Blood compatibility testing is conducted in a medical laboratory to identify potential incompatibilities between Human blood group systems, blood group systems in blood transfusion. It is also used to diagnose and prevent some complications of pr ...
for 13,000 soldiers of the
Second Australian Imperial Force The Second Australian Imperial Force (2nd AIF, or Second AIF) was the volunteer expeditionary force of the Australian Army in the Second World War. It was formed following the declaration of war on Nazi Germany, with an initial strength of one ...
. By the end of the war, Williams' team had performed blood typing for nearly 250,000 soldiers and numerous blood donors, all on a volunteer basis.


Death and legacy

Eleanor Williams died on 16 June 1963, aged 78. She was cremated, and her ashes were scattered at the
Springvale Botanical Cemetery The Springvale Botanical Cemetery is the largest crematorium and memorial park in Victoria, Australia, located in the southeastern Melbourne suburb of Springvale, Victoria, Springvale. History Originally known as The Necropolis Springvale, the c ...
. She was recognised with an obituary in ''
The Medical Journal of Australia The ''Medical Journal of Australia'' (MJA) is a peer-reviewed medical journal published 22 times a year. It is the official journal of the Australian Medical Association, published by Wiley on behalf of the Australasian Medical Publishing Compan ...
'', written by
Frank Macfarlane Burnet Sir Frank Macfarlane Burnet (3 September 1899 – 31 August 1985), usually known as Macfarlane or Mac Burnet, was an Australian virology, virologist known for his contributions to immunology. He won a Nobel Prize in Physiology or Medicine, Nobe ...
and Dr Ian Wood, which spoke of her 'remarkable knowledge, keen sense of humour, and tenacity of purpose'. In 1964, as part of their Golden Jubilee celebrations, the Red Cross Blood Transfusion Service named their new laboratories the F. Eleanor Williams Serological Research Laboratories in her honour.


References

{{DEFAULTSORT:Williams, Fannie Eleanor 1884 births 1963 deaths Australian medical researchers Australian Members of the Order of the British Empire Australian women of World War I Australian women scientists WEHI staff Associate members of the Royal Red Cross