Forkead box I3 (FOXI3) is a
protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residue (biochemistry), residues. Proteins perform a vast array of functions within organisms, including Enzyme catalysis, catalysing metab ...
that in humans is encoded by the ''FOXI3'' gene. FOXI3 is a
forkhead box
FOX (forkhead box) proteins are a family of transcription factors that play important roles in regulating the expression of genes involved in cell growth, proliferation, differentiation, and longevity. Many FOX proteins are important to embryonic ...
transcription factor
In molecular biology, a transcription factor (TF) (or sequence-specific DNA-binding factor) is a protein that controls the rate of transcription (genetics), transcription of genetics, genetic information from DNA to messenger RNA, by binding t ...
that is expressed in the development of hair and teeth. One of its mutations is a
dominant allele
In genetics, dominance is the phenomenon of one variant (allele) of a gene on a chromosome masking or overriding the effect of a different variant of the same gene on the other copy of the chromosome. The first variant is termed dominant and ...
responsible for the
heterozygous
Zygosity (the noun, zygote, is from the Greek "yoked," from "yoke") () is the degree to which both copies of a chromosome or gene have the same genetic sequence. In other words, it is the degree of similarity of the alleles in an organism.
Mos ...
Hh hairless trait in dogs. It was identified in 2008.
See also
*
Chinese Crested Dog
The Chinese Crested Dog is a hairless breed of dog. Like most hairless dog breeds, the Chinese Crested Dog comes in two varieties, without hair and with hair, which can be born in the same litter: the hairless and the powderpuff.
Description
T ...
*
Mexican Hairless Dog
The Xoloitzcuintle (or Xoloitzquintle, Xoloitzcuintli, or Xolo) is one of several breeds of hairless dog. It is found in standard, intermediate, and miniature sizes. The Xolo also comes in a coated variety, totally covered in fur. Coated and hair ...
*
Peruvian Inca Orchid (Peruvian Hairless Dog)
*
Dog coat genetics
Dogs have a wide range of coat colors, patterns, textures and lengths. Dog coat qualities are governed by how genes are passed from dogs to their puppies and how those genes are expressed in each dog. Dogs have about 19,000 genes in their genome b ...
References
{{Transcription factors, g3
Animal hair
Genes
Forkhead transcription factors