Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide is gamma chain of
high affinity IgE receptor
The high-affinity IgE receptor, also known as FcεRI, or Fc epsilon RI, is the high-affinity receptor for the Fc region of immunoglobulin E (IgE), an antibody isotype involved in allergy disorders and parasite immunity. FcεRI is a tetrameric ...
. This protein is encoded by the FCER1G
gene
In biology, the word gene has two meanings. The Mendelian gene is a basic unit of heredity. The molecular gene is a sequence of nucleotides in DNA that is transcribed to produce a functional RNA. There are two types of molecular genes: protei ...
in humans.
Function
The high affinity IgE receptor,
FcεRI, is a key molecule involved in allergic reactions. It is a tetramer composed of 1 alpha, 1 beta, and 2 gamma chains. The gamma chains are also subunits of other Fc receptors.
rovided by RefSeq, Jul 2008
References
Further reading
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Genes on human chromosome 1
{{gene-1-stub