
An exudate is a fluid emitted by an organism through pores or a wound, a process known as exuding or exudation.
''Exudate'' is derived from ''exude'' 'to ooze' from
Latin
Latin (, or , ) is a classical language belonging to the Italic branch of the Indo-European languages. Latin was originally a dialect spoken in the lower Tiber area (then known as Latium) around present-day Rome, but through the power ...
''exsūdāre'' 'to (ooze out) sweat' (''ex-'' 'out' and ''sūdāre'' 'to sweat').
Medicine
An exudate is any
fluid
In physics, a fluid is a liquid, gas, or other material that continuously deforms (''flows'') under an applied shear stress, or external force. They have zero shear modulus, or, in simpler terms, are substances which cannot resist any shear ...
that filters from the
circulatory system into
lesions or areas of
inflammation
Inflammation (from la, wikt:en:inflammatio#Latin, inflammatio) is part of the complex biological response of body tissues to harmful stimuli, such as pathogens, damaged cells, or Irritation, irritants, and is a protective response involving im ...
. It can be a pus-like or clear fluid. When an injury occurs, leaving skin exposed, it leaks out of the blood vessels and into nearby tissues. The fluid is composed of
serum
Serum may refer to:
*Serum (blood), plasma from which the clotting proteins have been removed
**Antiserum, blood serum with specific antibodies for passive immunity
* Serous fluid, any clear bodily fluid
* Truth serum, a drug that is likely to mak ...
,
fibrin
Fibrin (also called Factor Ia) is a fibrous, non-globular protein involved in the clotting of blood. It is formed by the action of the protease thrombin on fibrinogen, which causes it to polymerize. The polymerized fibrin, together with platele ...
, and
leukocytes. Exudate may ooze from cuts or from areas of infection or inflammation.
Types
* Purulent or suppurative exudate consists of plasma with both active and dead
neutrophils
Neutrophils (also known as neutrocytes or heterophils) are the most abundant type of granulocytes and make up 40% to 70% of all white blood cells in humans. They form an essential part of the innate immune system, with their functions varying in ...
,
fibrinogen, and
necrotic parenchymal cells
Parenchyma () is the bulk of functional substance in an animal organ or structure such as a tumour. In zoology it is the name for the tissue that fills the interior of flatworms.
Etymology
The term ''parenchyma'' is New Latin from the word � ...
. This kind of exudate is consistent with more severe infections, and is commonly referred to as
pus.
* Fibrinous exudate is composed mainly of
fibrinogen and
fibrin
Fibrin (also called Factor Ia) is a fibrous, non-globular protein involved in the clotting of blood. It is formed by the action of the protease thrombin on fibrinogen, which causes it to polymerize. The polymerized fibrin, together with platele ...
. It is characteristic of
rheumatic carditis, but is seen in all severe injuries such as
strep throat and
bacterial pneumonia. Fibrinous inflammation is often difficult to resolve due to blood vessels growing into the exudate and filling space that was occupied by fibrin. Often, large amounts of antibiotics are necessary for resolution.
*
Catarrhal exudate is seen in the nose and throat and is characterized by a high content of mucus.
* Serous exudate (sometimes classified as serous
transudate) is usually seen in mild inflammation, with relatively low protein. Its consistency resembles that of serum, and can usually be seen in certain disease states like
tuberculosis
Tuberculosis (TB) is an infectious disease usually caused by ''Mycobacterium tuberculosis'' (MTB) bacteria. Tuberculosis generally affects the lungs, but it can also affect other parts of the body. Most infections show no symptoms, in w ...
. (See below for difference between transudate and exudate)
* Malignant (or cancerous) pleural effusion is effusion where
cancer cells are present. It is usually classified as exudate.
Types of exudates: Serous, Serosanguineous, Sanguineous, Hemorrhaging and Purulent drainage.
Serous: Clear straw colored liquid that drains from the wound this is a normal part of the healing process.
Serosanguineous: Small amount of blood is present in the drainage it is pink in color due to the presence of red blood cells mixed with serous drainage. This is a normal part of the healing process
Sanguineous: This type of drainage contains red blood due to trauma of blood vessels, this may occur while cleaning the wound. Sanguineous drainage is abnormal.
Hemorrhaging: This type of drainage contains frank blood from a leaking blood vessel. This will require emergency treatment to control the bleed. This type of drainage is abnormal.
Purulent drainage: This type of drainage is malodorous and can be yellow, gray, or greenish in color. This is an indication of an infection.
Exudates vs. transudates
There is an important distinction between
transudates and exudates. Transudates are caused by disturbances of
hydrostatic or
colloid osmotic pressure, not by inflammation. They have a low protein content in comparison to exudates. Medical distinction between transudates and exudates is through the measurement of the
specific gravity of extracted fluid. Specific gravity is used to measure the protein content of the fluid. The higher the specific gravity, the greater the likelihood of
capillary permeability changes in relation to
body cavities. For example, the specific gravity of the transudate is usually less than 1.012 and a protein content of less than 2 g/100 mL (2 g%).
Rivalta test may be used to differentiate an exudate from a transudate.
It is not clear if there is a distinction in the difference of transudates and exudates in plants.
Plant exudates
Plant exudates include
saps SAPS may refer to:
Science and technology
* SAPS II (Simplified Acute Physiology Score), a severity of disease classification system
** SAPS III (Simplified Acute Physiology Score), a system for predicting mortality
* Stand-alone power system, wher ...
,
gums,
latex, and
resin. Sometimes
nectar
Nectar is a sugar-rich liquid produced by plants in glands called nectaries or nectarines, either within the flowers with which it attracts pollinating animals, or by extrafloral nectaries, which provide a nutrient source to animal mutualists ...
is considered an exudate. Plant seeds exudate a variety of molecules into the
spermosphere,
and
roots exudate into the
rhizosphere, these exudates include acids, sugars,
polysaccharides and
ectoenzymes; this can account for 40% of root carbon. Exudation of these compounds has various benefits to the plant and to the
microorganisms
A microorganism, or microbe,, ''mikros'', "small") and ''organism'' from the el, ὀργανισμός, ''organismós'', "organism"). It is usually written as a single word but is sometimes hyphenated (''micro-organism''), especially in olde ...
of the rhizosphere.
See also
*
Guttation
*
Pleural effusion
*
Scarless wound healing
*
Surfactant leaching
Surfactant leaching of acrylic (latex) paints, also known as exudate staining, streak staining, streaking, weeping, exudation, etc., occurs when the freshly painted surface becomes wet and water-soluble components of the paint (dispersants, surf ...
References
External links
*
{{Inflammation
Cardiovascular physiology
Body fluids