Expanded Criteria Donor (ECD) is normally associated with

kidney In humans, the kidneys are two reddish-brown bean-shaped blood-filtering organ (anatomy), organs that are a multilobar, multipapillary form of mammalian kidneys, usually without signs of external lobulation. They are located on the left and rig ...

donors. They are also referred to as donors with "medical complexities". ECD donors are normally aged 60 years or older, or over 50 years with at least two of the following conditions:

hypertension Hypertension, also known as high blood pressure, is a Chronic condition, long-term Disease, medical condition in which the blood pressure in the artery, arteries is persistently elevated. High blood pressure usually does not cause symptoms i ...

history, serum

creatinine Creatinine (; ) is a breakdown product of creatine phosphate from muscle and protein metabolism. It is released at a constant rate by the body (depending on muscle mass). Biological relevance Serum creatinine (a blood measurement) is an impor ...

> 1.5 mg/dl or cause of death from

cerebrovascular accident Stroke is a medical condition in which poor blood flow to a part of the brain causes cell death. There are two main types of stroke: ischemic, due to lack of blood flow, and hemorrhagic, due to bleeding. Both cause parts of the brain to stop ...

. Of the 9319 living

kidney donation Kidney transplant or renal transplant is the organ transplant of a kidney into a patient with end-stage kidney disease (ESRD). Kidney transplant is typically classified as deceased-donor (formerly known as cadaveric) or living-donor transplantati ...

s reported in the American Organ Procurement and Transplantation Network (OPTN) / United Network for Organ Sharing ( UNOS) database from July 2004 to December 2005, 368 (4.0%) donors were over the age of 60 (of which 86 .9%were over the age of 65), 956 (10.3%) had hypertension, 2785 (29.9%) had an eGFR < 80 mL/min per 1.73 m2 (of which 392 .2%had an eGFR < 60 mL/min per 1.73 m2) and 1194 (12.8%) had a BMI > 30 kg/m2 (of which 250 .7%had a BMI > 35 kg/m2)Iordanous, Y. et al. Recipient Outcomes for Expanded Criteria Living Kidney Donors: The Disconnect Between Current Evidence and Practice. American Journal of Transplantation 2009; 9: 1558–1573 The concept of ECD was raised to address the discrepancy between demand and supply in

kidney transplantation Kidney transplant or renal transplant is the organ transplant of a kidney into a patient with end-stage kidney disease (ESRD). Kidney transplant is typically classified as deceased-donor (formerly known as cadaveric) or living-donor transplantat ...

References

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External links

UNOS
United Network of Organ Sharing.
Organ Procurement and Transplant Network
OPTN Transplantation medicine Organ donation